The Tongshan intrusion is located at the Guichi ore cluster field along the Lower Yangtze River metallogenic belt (LYRB) in eastern China. Elemental data and major elements of biotite are reported for Late Mesozoic plutons in the Guichi ore cluster in the Middle-Lower Yangtze River Region, attempting to explain their diagenetic age, petrogenesis, and tectonic implications. The Tongshan intrusion is dated at 146.3±3.2 Ma, with zircon εHf(t) average value of -5.23, illustrating that the Tongshan intrusion could be derived from crust mantle mixing magmatite provenance. The two-stage Hf model ages between 1184~1422 Ma is indicated magma source relationship with those of the Mesoproterozoic basement in south Anhui. The Tongshan intrusion is high-K calc-alkaline, and exhibit adakite-like geochemical feature, such as high Al2O3, Sr contents, Sr/Y value, low Y and Yb contents. The geochemical and reexplained published isotopic data indicate that these adakites are most likely from partial melting of subducted oceanic crust, and mixed with enriched lithospheric mantle components in the rising process.
a1_The long-term feeding of a high-concentrate diet (the concentrate ratio is greater than 60 %) leads to mammary gland inflammatory response in ruminants and decreased quality in dairy cows and affects the robust development of the dairy industry. The main reason is closely related to elevated lipopolysaccharide (LPS) in the body. In this experiment, a bovine mammary epithelial cell line (MAC-T) was used as a model, and LPS at different concentrations (0 ng/ml, 1 ng/ml, 10 ng/ml, 100 ng/ml, 1000 ng/ml, 10000 ng/ml) was added to the cells. The cell survival rate, oxidative stress indicators, total lipid droplet area, triglyceride content and key genes regulating lipid metabolism were detected by 3-(4,5)-dimethylthiahiazo(-z-y1)- 3,5-di-phenytetrazoliumromide (MTT), assay kit, microscope observation and RT-PCR methods to explore the regulatory mechanism of mammary health and milk fat synthesis.The results showed that compared with those of the control group, the survival rates of cells were significantly decreased after 9 h of stimulation with 1000 ng/ml and 10000 ng/ml LPS (P<0.01).The contents of superoxide dismutase (SOD), catalase (CAT) and total antioxidant capacity (T-AOC) in cells were significantly decreased (P<0.05).Compared with that of the control group, the content of malondialdehyde (MDA) in cells was significantly increased (P<0.05) after stimulation with 10000 ng/ml LPS for 9 h. After 9 h of stimulation with 100 ng/ml, 1000 ng/ml and 10000 ng/ml LPS, the total lipid drop area and triglyceride (TG) content of MAC-T cells were significantly decreased (P<0.05).The expression levels of fatty acid synthesis-related genes AcetylCoA carboxylase (ACC) and Stearoyl-CoA desaturase 1 (SCD-1) were significantly decreased after 9 h of stimulation with 100 ng/ml, 1000 ng/ml and 10000 ng/ml LPS (P<0.05), while the expression levels of Fatty Acid synthetase (FAS) were significantly decreased after stimulation with 1000 ng/ml and 1000 ng/ml LPS (P<0.05)., Lin Li, Weibin Tang, Mei Zhao, Binbin Gong, Meng Cao, Jianyuan Li., and Obsahuje bibliografii