This was a comment during an interview with Professor Vaclay Pates, a renowned Czech biochemist, for a feature article in this issue. The Academy of Sciences of the Czech Republic (ASCR) has been observing the 20m anniversary of its inception, of which this is a part. Professor PaOes was President of the Academy (2005-2009) and also of the Learned Society of the Czech Republic (2010-2012). His scientific speciality is genomics. His research group was among the first to completely sequence a genome, namely, the DNA of a bacterial virus. In addition, he discovered a specific enzyme involved in the catabolism of the plant hormone cytokinine. He co-authored of the first Czech synthetic gene (the precursor of the neurotransmitter enkefaline). and Marina Hužvárová.