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Start Over Creator Jiří Velek

1. Influence of active immunization against angiotensin AT1 or AT2 receptor on hypertension development in young and adult SHR

Creator:
Blanka Železná, Leopold Veselský, Jiří Velek, Zdena Dobešová, Josef Zicha, and Jaroslav Kuneš
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, krevní tlak, hypertrofie srdce, blood pressure, heart hypertrophy, spontaneously hypertensive rats, active immunization, angiotensin AT1 receptor, angiotensin AT2 receptor, kidney weight, 14, and 612
Language:
English
Description:
B. Železná, L. Veselský, J. Velek, Z. Dobešová, J. Zicha, J. Kuneš. and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

2. Somatotropin has no effect on the quantity of guanine nucleotide binding proteins Gqalpha/G11alpha in goat adipose tissue in vivo

Creator:
Krbeček, V., Hana Kovářů, Josef Škarda, Tomislav Barth, Jiří Velek, and Žižkovský, V.
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, tuková tkáň, kozy, adipose tissue, goats, samatotropin, g-proteins, 14, and 612
Language:
English
Description:
The decapeptide QLNLKEYNLV corresponding to the C-terminus of Gq/G11alpha guanine nucleotide-binding proteins (G-proteins) was synthesized by the solid-phase method and conjugated to keyhole limpet hemocyanin. The rabbits were immunized with these conjugates and an antiserum that reacted specifically with the alpha subunit of Gq/G11 proteins was used in this study. The antiserum exhibited no cross-reactivity with the alpha subunits of stimulatory (Gs) or inhibitory (Gi) G-proteins associated with adenylate cyclase. Immunoblots with the antiserum showed that it specifically recognized the Gq/G11 alpha-proteins in cholate extracts of adipose tissue membranes of goats. Treatment of young castrated male goats with bST had no effect on the quantity of Gq/G11 alpha-subunits in adipose tissue and the results thus obtained did not support the idea that the bST signal in adipose tissue is transmitted via Gq/G11 alpha-proteins., V. Krbeček, H. Kovářů, J. Škarda, T. Barth, J. Velek, V. Žižkovský., and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public