Measuring evaporation and transpiration at the field scale is complicated due to the heterogeneity of the environment, with point measurements requiring upscaling and field measurements such as eddy covariance measuring only the evapotranspiration. During the summer of 2014 an eddy covariance device was used to measure the evapotranspiration of a growing maize field at the HOAL catchment. The stable isotope technique and a Lagrangian near field theory (LNF) were then utilized to partition the evapotranspiration into evaporation and transpiration, using the concentration and isotopic ratio of water vapour within the canopy. The stable isotope estimates of the daily averages of the fraction of evapotranspiration (Ft) ranged from 43.0–88.5%, with an average value of 67.5%, while with the LNF method, Ft was found to range from 52.3–91.5% with an average value of 73.5%. Two different parameterizations for the turbulent statistics were used, with both giving similar R2 values, 0.65 and 0.63 for the Raupach and Leuning parameterizations, with the Raupach version performing slightly better. The stable isotope method demonstrated itself to be a more robust method, returning larger amounts of useable data, however this is limited by the requirement of much more additional data.
Cíl. Cílem studie bylo popsat partnerské strachy typické pro období mladé dospělosti a zjistit, zda existují faktory, které predikují výskyt a intenzitu partnerských strachů v tomto období. Vzorek. Vzorek tvořilo 407 respondentů z longitudinálního projektu „Cesty do dospělosti“ (81 % žen, průměrný věk = 23,53 let; SD = 1,48; Min = 18,7, Max = 33). Metoda. Data byla získávána pomocí online dotazníků. Výpovědi o partnerských straších byly získávány metodou volných výpovědí. Dále byly administrovány tyto dotazníky- ECR-RS, QMI, Ex-bond. Výsledky. Volné výpovědi o subjektivně prožívaných straších byly kategorizovány do sedmi kategorií za pomoci tematické analýzy (Strachy z rozchodu, ze samoty, z nenalezení partnera, z partnerských neshod, s pochybnostmi o sobě v partnerství, z nevěry a generalizované partnerské strachy). Z výsledků regresní analýzy vyplývá, že existuje vztah mezi výskytem partnerských strachů, prožitkem rozchodu a vazbovou úzkostností k partnerovi. Dále byl detekován vztah mezi intenzitou partnerských strachů a pohlavím, existencí partnerského vztahu a opět vazbovou úzkostností k partnerovi. Limity. Limitem studie bylo především složení výzkumného souboru, kde byl významný nepoměr mužů a žen, vysokoškoláků a pracujících a také větší podíl respondentů starší věkové skupiny. and Objectives. The study aims at describe partnership fears in the young adulthood period and to examine the relationship between some factors (age, gender, attachment, break up, relationship with a partner) and presence and intensity of partnership fears. Sample. Overall, this study was participated in by 407 respondents from the longitudinal project “Cesty do dospělosti” (81% of women, the average age of the respondents was 23.53 years SD = 1,48; Min = 18,7, Max = 33). Method. Questionnaires were collected on-line (QMI, ECRRS, Ex-Bond). Partnerships fears were collected by open-ended questions on fears. Results. The open-ended answers were categorized by using thematic analysis, into 7 categories (Fear of breaking up, of remaining alone, of not finding a partner, of partners disagreements, fears associated with a sense of the incompetence in partnership, of infidelity and generalized partnership fears). Multiple regression analysis indicated that the anxious attachment dimension to the partner and the experience of break up were found to be significant predictors of the presence of partnership fears. The gender, the existence of partnership and attachment anxiety to the partner were found to be significant predictors of the intensity of partnership fears. Limits. The study impact is limited by the sample structure. The sample was over-represented by women, students and respondents of older age group.
Abiotic and biotic factors determine success or failure of individual organisms, populations and species. The early life stages are often the most vulnerable to heavy mortality due to environmental conditions. The deer ked (Lipoptena cervi Linnaeus, 1758) is an invasive insect ectoparasite of cervids that spends an important period of the life cycle outside host as immobile pupa. During winter, dark-coloured pupae drop off the host onto the snow, where they are exposed to environmental temperature variation and predation as long as the new snowfall provides shelter against these mortality factors. The other possible option is to passively sink into the snow, which is aided by morphology of pupae. Here, we experimentally studied passive snow sinking capacity of pupae of L. cervi. We show that pupae have a notable passive snow sinking capacity, which is the most likely explained by pupal morphology enabling solar energy absorption and pupal weight. The present results can be used when planning future studies and when evaluating possible predation risk and overall survival of this invasive ectoparasite species in changing environmental conditions., Sirpa Kaunisto, Hannu Ylönen, Raine Kortet., and Obsahuje bibliografii
Experimental studies in animals provide relevant knowledge about pathogenesis of radiation-induced injury to the central nervous system. Radiation-induced injury can alter neuronal, glial cell population, brain vasculature and may lead to molecular, cellular and functional consequences. Regarding to its fundamental role in the formation of new memories, spatial navigation and adult neurogenesis, the majority of studies have focused on the hippocampus. Most recent findings in cranial radiotherapy revealed that hippocampal avoidance prevents radiation-induced cognitive impairment of patients with brain primary tumors and metastases. However, numerous preclinical studies have shown that this problem is more complex. Regarding the fact, that the radiation-induced cognitive impairment reflects hippocampal and non-hippocampal compartments, it is highly important to investigate molecular, cellular and functional changes in different brain regions and their integration at clinically relevant doses and schedules. Here, we provide a literature review in order support the translation of preclinical findings to clinical practice and improve the physical and mental status of patients with brain tumors.
Diabetic nephropathy, included in diabetic kidney disease (DKD), is the primary disease leading to end-stage renal disease (ESRD) or dialysis treatment, accounting for more than 40 % of all patients with ESRD or receiving dialysis. Developing new therapeutics to prevent the transition to ESRD or dialysis treatment requires an understanding of the pathophysiology of DKD and an appropriate animal model for drug efficacy studies. In this study, we investigated the pathophysiology of diabetic kidney disease with type 2 diabetes in uninephrectomized db/db mice. In addition, the nephrectomized db/db mice from 10 weeks to 42 weeks were used to assess the efficacy of longterm administration of the angiotensin-II–receptor antagonist losartan. The blood and urinary biochemical parameters and the blood pressure which is a main pharmacological endpoint of the losartan therapy, were periodically measured. And at the end, histopathological analysis was performed. Uninephrectomized db/db mice clearly developed obesity and hyperglycemia from young age. Furthermore, they showed renal pathophysiological changes, such as increased urinary albumin-creatinine ratio (UACR) (the peak value 3104±986 in 40-week-old mice), glomerular hypertrophy and increased fibrotic areas in the tubulointerstitial tubules. The blood pressure in the losartan group was significantly low compared to the normotensive Vehicle group. However, as expected, Losartan suppressed the increase in UACR (829±500) indicating the medication was sufficient, but the histopathological abnormalities including tubular interstitial fibrosis did not improve. These results suggest that the uninephrectomized db/db mice are useful as an animal model of the severe DKD indicated by the comparison of the efficacy of losartan in this model with the efficacy of losartan in clinical practice.
Extreme or unaccustomed eccentric exercise can cause exerciseinduced muscle damage, characterized by structural changes involving sarcomere, cytoskeletal, and membrane damage, with an increased permeability of sarcolemma for proteins. From a functional point of view, disrupted force transmission, altered calcium homeostasis, disruption of excitation-contraction coupling, as well as metabolic changes bring about loss of strength. Importantly, the trauma also invokes an inflammatory response and clinically presents itself by swelling, decreased range of motion, increased passive tension, soreness, and a transient decrease in insulin sensitivity. While being damaging and influencing heavily the ability to perform repeated bouts of exercise, changes produced by exercise-induced muscle damage seem to play a crucial role in myofibrillar adaptation. Additionally, eccentric exercise yields greater hypertrophy than isometric or concentric contractions and requires less in terms of metabolic energy and cardiovascular stress, making it especially suitable for the elderly and people with chronic diseases. This review focuses on our current knowledge of the mechanisms underlying exerciseinduced muscle damage, their dependence on genetic background, as well as their consequences at the structural, functional, metabolic, and clinical level. A comprehensive understanding of these is a prerequisite for proper inclusion of eccentric training in health promotion, rehabilitation, and performance enhancement., Andraž Stožer, Peter Vodopivc, Lidija Križančić Bombek., and Obsahuje bibliografii
Fleas infecting northern white-breasted hedgehogs, Erinaceus roumanicus (Barrett-Hamilton), collected from 2009-2011 in Budapest (Hungary) were studied. A total of 305 white-breasted hedgehogs were captured and 1,251 fleas were collected. The flea community comprised two species, the hedgehog flea Archaeopsylla erinacei (Bouche, 1835) and the dog flea Ctenocephalides canis (Curtis, 1826), although the latter was only found on three hedgehogs. Fleas were found on half of the host specimens (51%; n = 156) where their distribution was strongly aggregated. The sex ratio of A. erinacei was biased towards females and was correlated with host size. Interestingly, the sex ratio of fleas became more equal on heavier hosts. It had been expected that, under high competition, the sex ratio would be female biased because it is known that female ectoparasites dominate on poorer hosts. The body size of a random sample of 200 fleas (100 female and 100 male) was measured under a microscope. The analyses showed directional asymmetry in two features - the distance between the top of the head and the eye, and head length. In this two body traits the left side was significantly greater than right side in both sexes of A. erinacei. Our data shed light on the complex nature of the flea population infecting northern white-breasted hedgehogs in an urban area., Krzysztof Dudek, Gábor Földvári, Viktória Majláthová, Igor Majláth, Krisztina Rigó, Viktor Molnár, Mária Tóth, Łukasz Jankowiak, Piotr Tryjanowski., and Obsahuje bibliografii
In mammalian carnivore guilds (order Carnivora), spatiotemporal partitions play a major role in reducing competitive confrontations and facilitating successful sympatry. Using camera-trapping techniques, the present study aimed to elucidate patterns of spatial distribution and diel activities among medium- and large-sized carnivore species across central Bulgaria. We obtained 3,364 images of nine focal carnivores from 13,988 camera-trapping days between 2015 and 2020. Our findings indicated that the spatial distribution of the focal carnivore guilds varied with changes in altitudinal gradient, ruggedness, and forest-agricultural landscape changes. Specifically, the two largest species, the grey wolf (Canis lupus Linnaeus, 1758) and the brown bear (Ursus arctos Linnaeus, 1758), were found only in the Balkan Mountains, whereas the largest mesocarnivore, the golden jackal (Canis aureus Linnaeus, 1758), was mainly distributed agricultural lowlands. The European wildcat (Felis sylvestris Schreber, 1777) was found in forests inside protected areas, and other mesocarnivores were distributed at intermediate levels between wooded-mountains and agricultural lowlands. Brown bear, golden jackal, and domestic dog (Canis lupus familiaris Linnaeus, 1758) showed cathemeral, crepuscular, and diurnal activity, respectively, whereas the remaining six carnivores showed nocturnal activity in synchrony with their main prey. Our findings indicated that anthropogenic landscape modifications and potential interspecific competition resulted in patterns of spatial distribution and temporal activity in this carnivore guild.