Orthopaedists in the Czech Republic use corrective braces of type Cheneau or Cerny for conservative treatment of non skeletal scoliosis. The brace has force effects on a child spine and if it is used for enough long time the spine defect is corrected. The brace is made individually for each patient in this way: first, the negative plaster form of a child trunk and then the positive plaster form are made. The positive plaster form is deepened in the places where brace has to push on the patient trunk. The laminate brace made according to this plaster form pushes the child trunk like a tight shoe principle. The paper shows the manner of determination and computer algorithms for solving of the stress state in vertebrae and inter-vertebrae discs and the spinal curve correction under brace force effects for a concrete child patient. The pathologic spinal curve deformities are measured on the X-ray of patient. The spine stress state and spine deformation correction are solved as a beam (spine) on an elastic ground (soft tissue). There are used two algorithms. The 1st algorithm solves the spine stress state and deformation under brace force effect given by displacements of trunk surface. The 2nd algorithm has as input the spinal curves of a patient with and without brace measured on the X-rays. The difference of the two curves is the spine deformity corretions and the spine stress state and necessary trunk surface displacement are the results. If the ideal spine curve is set as the curve under brace effect then the trunk surface is equal to the optimal brace form. The calculation algorithm and parameters ware verified with treatment courses. The trunk surface load was checked by sensor plates which ware put into braces to measure the load values between the brace and the child trunk surface. and Obsahuje seznam literatury
Článek vychází ze zkušeností autora, který se po dlouhé praxi ve výuce mechaniky a výzkumu v oboru fyziky polymerů nyní převážně zabývá biomechanikou. Impresionistickou metodou se snaží na několika příkladech ukázat, jak vidí úlohu mechaniky a především mechaniky kontinua a reologie v biomechanice. Zabývá se i otázkou vzájemných vztahů různých profesí v multidisciplinárním oboru. Úlohu mechaniky v biomechanice vidí především v co nejhlubším pochopení fyzikální podstaty biologických dějů a jejich co nejadekvátnějším vyjádřením v rámci fyziky, kterou je však často nutno užívat ve formě podstatně složitější, než je fyzika středoškolská., This article is based on the author's experiences as both a university lecturer of mechanics and a researcher in polymer physics working now in biomechanics. The impression of the role of mechanics in biomechanics is shown on several examples taken mainly from the author's experience. The interrelations of different processes engaged in the multidisciplinary biomechanics are also discussed. The role of mechanics in biomechanics is seen in deep physical understanding of the solved problem and in adequate physical interpretation of the gained results. As the biomechanical problems are often very difficult to solve, the more general physics that is that taught at grammar schools must be used. The physician's knowledge of the human body functions are so deep that only the main features of the knowledge may be expressed in physical terms even if very advanced theories are used., Antonín Havránek., and Obsahuje bibliografii
Pro řadu biomedicínských aplikací je zásadní interakce mezi biologickým prostředím a povrchem pevné látky. Diamant jako materiál sdružuje v tomto ohledu výborné polovodičové, mechanické, chemické i biologické vlastnosti a lze ho připravovat synteticky i na velké plochy. Zde ukazujeme, jaký vliv má atomární zakončení povrchu diamantu na uspořádání proteinů a buněk a jak toto biologické rozhraní naopak ovlivňuje jeho elektronické vlastnosti. Dosažené poznatky jsou přínosné pro využití unikárních vlastností diamantu v medicíně a dalších oborech., Understanding interactions between the biological environment and solid state surfaces is crucial for a wide range of biomedical applications. In this context, diamond as a material merges excellent semiconducting, mechanical, chemical as well as biological properties and it can be prepared synthetically even at large areas. here we show how atomic termination of diamond surfaces inluences arrangement of proteins and cells and how such biological interface influences electronic properties of diamond. Attained knowledge is fundamental for employing diamond unique properties in medicine and other fields., Bohuslav Rezek, Egor Ukraintsev, Marie Krátká, Alexander Kromka, Antonín Brož, Marie Kalbáčová., and Obsahuje bibliografii
The study of natural materials, a creating of their similarities from the point of view of constructions, structures and materials is relatively new and a perspective field connecting results of scientific research of biologists, chemists, physicists, material engineers, constructors and designers. At present day a lot of these results were transferred into the industry application. How we can see natural materials could become a source of inspiration on a field of materials, technologies and constructions as well as on the field of nanotechnologies. and Studium přírodních materiálů, vytváření jejich analogií z hlediska konstrukcí, struktur i materiálů je relativně novým a neobyčejně perspektivním oborem, který dokáže spojovat výsledky bádání biologů, chemiků, fyziků, materiálových inženýrů, konstruktérů a designérů. V současné době řada výsledků těchto výzkumů dosáhla i svých průmyslových aplikací. Jak je postupně zjišťováno, přírodní materiály se nám mohou stát zdrojem inspirace v oblasti materiálů, technologií a konstrukcí stejně tak jako v oblasti nanotechnologií.
Globally, water deficit is one of the major constraints in chickpea (Cicer arietinum L.) production due to substantial reduction in photosynthesis. Photorespiration often enhances under stress thereby protecting the photosynthetic apparatus from photoinhibition. Application of bioregulators is an alternative to counter adverse effects of water stress. Thus, in order to analyze the role of bioregulators in protecting the photosynthetic machinery under water stress, we performed an experiment with two contrasting chickpea varieties, i.e., Pusa 362 (Desi type) and Pusa 1108 (Kabuli type). Water deficit stress was imposed at the vegetative stage by withholding water. Just prior to exposure to water stress, plants were pretreated with thiourea (1,000 mg L-1), benzyladenine (40 mg L-1), and thidiazuron (10 mg L-1). Imposed water deficit decreased relative water content (RWC), photosynthetic rate (P N), quantum efficiency of PSII (Fv/Fm), and enhanced lipid peroxidation (LPO). However, bioregulator application maintained higher RWC, P N, Fv/Fm, and lowered LPO under water stress. Expression of Rubisco large subunit gene (RbcL) was low under water stress both in the Kabuli and Desi type. However, bioregulators strongly induced its expression. Although poor expression of two important photorespiratory genes, i.e., glycolate oxidase and glycine decarboxylase H subunit, was observed in Desi chickpea under imposed stress, bioregulators in general and cytokinins in particular strongly induced their expression. This depicts that the application of bioregulators protected the photosynthetic machinery by inducing the expression of RbcL and photorespiratory genes during water deficit stress., T. V. Vineeth, P. Kumar, G. K. Krishna., and Obsahuje seznam literatury
V tomto článku je nastíněn základní úvod do problematiky biotransformace a jejich možných negativních důsledků. V textu jsou popsány tři fáze biotransformace a u každé z nich případ, se kterým se čtenář ve svém životě může setkat. Dále je zde jednoduchým způsobem vysvětlena nomenklatura biotransformačních enzymů a transportérů a článek tak celkově poskytuje základní povědomí o komplexnosti biotransformace., This article outlines a basic introduction to the topic of biotransformation and its possible negative consequences. The text describes three phases of biotransformation and each is presented in an example which the reader may encounter in everyday life. Furthermore, in a simple way, the nomenclature of biotransformation enzymes and transporters is explained and thus the paper provides a basic understanding of the complexity of biotransformation., and Ondřej Ženata.
In the past decades, it has become clear that superoxide radical (O2 .-) can be generated from photosystem II (PSII) during photosynthesis. Depending on the extent of its accumulation, O2 .- plays an important role in plant physiology and pathology. The photoinhibition/repair cycle is a typical process in PSII which is mainly responsible for the survival of plants under the photoinihibition condition. It is therefore of significant importance to determine O2 .- production in this cycle, and then explore how O2 .- is controlled by PSII within a normal physiological level. With this in mind, we herein investigate the variation of the O2 .- levels in PSII under Mn-depleted and photoactivated conditions mimicking the photoinhibition/repair cycle in vitro. The effect of intrinsic SOD-like component on the O2 .- levels was also studied. Results show that PSII has the ability to regulate the O2 .- levels in these two processes by simultaneously modulating the O2 .- generation activity and intrinsic SOD-like activity. This finding could shed new lights on the photoprotective property of PSII against O2 .- and other reactive oxygen species. and Y. G. Song ... [et al.].
To determine the role of postinspiratory inspiratory activity of the diaphragm in the biphasic ventilatory response to hypoxia in unanesthetized rats, we examined diaphragmatic activity at its peak (DI), at the end of expiration (DE), and ventilation in adult unanesthetized rats during poikilocapnic hypoxia (10 % O2) sustained for 20 min. Hypoxia induced an initial increase in ventilation followed by a consistent decline. Tidal volume (VT), frequency of breathing (fR), DI and DE at first increased, then VT and DE decreased, while fR and DI remained enhanced. Phasic activation of the diaphragm (DI - DE) increased significantly at 10, 15 and 20 min of hypoxia. These results indicate that 1) the ventilatory response of unanesthetized rats to sustained hypoxia has a typical biphasic character and 2) the increased end-expiratory activity of the diaphragm limits its phasic inspiratory activation, but this increase cannot explain the secondary decline in tidal volume and ventilation., H. Maxová, M. Vízek., and Obsahuje bibliografii
A total of 22 specimens of whiting Merlangius merlangus (L.) (Teleostei, Gadidae) from the northern Øresund, Denmark were examined for Myxosporea. Zschokkella hildae Auerbach, 1910 (Myxidiidae), Gadimyxa sp. (Parvicapsulidae) and a species of Bipteria occurred in the renal tubules of 9%, 18% and 68% whiting, respectively. Immature spores of the Bipteria species are very similar to spores of Myxoproteus formosus Kovaleva et Gaevskaya, 1979 originally described from the urinary system of whiting from the Celtic Sea. We therefore consider Bipteria sp. from whiting in Denmark conspecific with M. formosus and propose Bipteria formosa (Kovaleva et Gaevskaya, 1979) comb. n. The spore of Bipteria formosa is described in detail and compared with other Bipteria spp. The phylogenetic position of B. formosa, based on partial 18S rDNA sequences, is closest to Leptotheca fugu Tun, Yokoyama, Ogawa et Wakabayashi, 2000 and the Sphaerosporidae.
In 2005, we dissected 102 wildfowl from the Czech Republic and 73 wildfowl from Poland including representatives of Anseriformes, Gruiformes and Gaviiformes. Schistosome infection was found in a total of 21 (29%) and 23 (23%) birds from Poland and the Czech Republic, respectively. All infected birds belonged to the order Anseriformes. The prevalences of nasal and visceral species were, respectively, 22% and 16% in Poland and 6% and 19% in the Czech Republic. Four species of schistosomes were found: Bilharziella polonica Kowalewski, 1895, Trichobilharzia regenti Horák, Kolářová et Dvořák, 1998, T. szidati Neuhaus, 1952, and an undetermined schistosome from the intestinal wall of Anas penelope L. The finding of T. szidati represents the first record of the parasite from natural final host since the species description.