Erythromycin has a well-known dual effect on the contractility of the gastrointestinal system and recently has also been shown to inhibit contractions of the rat myometrium. The aim of the present study was to investigate the effects of clarithromycin on oxytocin, prostaglandin F2a (PGF2a) and KCl-induced contractions of human myometrium in vitro. Myometrial strips were obtained from pregnant women undergoing elective Cesarean section and the strips were suspended in a jacketed organ bath filled with Krebs solution at 37 oC (pH 7.4) and continuously aired with 95 % oxygen and 5 % carbon dioxide. Isometric contractions were measured using a force displacement transducer. Oxytocin, PGF2a, KCl and clarithromycin were applied to the tissue bath and the amplitude and frequency of contractions were evaluated at 20-min intervals. Freidmann analysis of variance, Kruskal Wallis and Wilcoxon Rank tests were used for statistical analysis of the data. Clarithromycin dose dependently inhibited the amplitude of contractions independent of the stimulus. Pre-treatment with apamin prevented clarithromycin-induced effects on amplitude and frequency of contractions. We conclude that the macrolide antibiotic clarithromycin may have a direct inhibitory effect on contractions of human myometrium., H. Celik, A. Ayar., and Obsahuje bibliografii
Článek se zabývá některými vlastnostmi nevalenčních doplnění ve španělštině. Zkoumá hranici mezi valenčními a nevalenčními doplněními a posuzuje vhodnost některých formálních testů pro rozlišování mezi oběma typy. Jádrem článku je sémantická klasifikace nevalenčních doplnění španělských adjektiv, doplněná o charakteristiku jednotlivých sémantických tříd. V závěru je věnována pozornost adjektivům složeným z adjektiva a jeho nevalenčního komplementu.
Královská kanonie premonstrátů na Strahově - Strahovská knihovna Praha CZ BR V 42/47, Královská kanonie premonstrátů na Strahově - Strahovská knihovna Praha CZ BU II 112/20, Královská kanonie premonstrátů na Strahově - Strahovská knihovna Praha CZ BO VI 58/16, Knihovna Akademie věd ČR Praha CZ TF 347 adl. 42 def., Národní knihovna ČR Praha CZ 46 F 81 adl. 8, Klášter Rytířského řádu křižovníků s červenou hvězdou - knihovna Praha CZ XVI H 8 adl. 1, Metropolitní kapitula u sv. Víta v Praze Praha CZ F.b.149 adl. 13, Metropolitní kapitula u sv. Víta v Praze Praha CZ F.b.271 adl. 16, and BCBT12091
A Lie algebra $L$ is called 2-step nilpotent if $L$ is not abelian and $[L, L]$ lies in the center of $L$. 2-step nilpotent Lie algebras are useful in the study of some geometric problems, and their classification has been an important problem in Lie theory. In this paper, we give a classification of 2-step nilpotent Lie algebras of dimension 9 with 2-dimensional center., Ren Bin, Zhu Lin Sheng., and Obsahuje bibliografii
Let R be a commutative ring with nonzero identity and J(R) the Jacobson radical of R. The Jacobson graph of R, denoted by JR, is defined as the graph with vertex set RJ(R) such that two distinct vertices x and y are adjacent if and only if 1 − xy is not a unit of R. The genus of a simple graph G is the smallest nonnegative integer n such that G can be embedded into an orientable surface Sn. In this paper, we investigate the genus number of the compact Riemann surface in which JR can be embedded and explicitly determine all finite commutative rings R (up to isomorphism) such that JR is toroidal., Krishnan Selvakumar, Manoharan Subajini., and Obsahuje seznam literatury
The Schism from 1378 evoked an essential need for a redefinition of doctrinal authority within the church. One of the aims of this study is to show that the Council of Constance did not condemn Hus’ theses only from the doctrinal perspective but also endeavoured to consolidate a certain modus procedendi in relation to the scholar’s heresy. In the context of Hus’ cause, it is evident that the doctrinal questions had great gravity in the eyes of the council fathers. Most likely for the reason of this great attention being paid to the theological aspects, attention was not paid to the fact that in parallel with the condemnation of Hus’ theses some of the main representatives of the council endeavoured for the consolidation of a certain modus procedendi in the cases of the processes whose beginning can be found within the universities. Both in the case of Wycliffe and in the case of Hus, the council confirmed the previous condemnation of university instances in accord with ecclesiastical power. The promise of a public hearing of Hus aroused great disorder, because in that two entirely opposing evidential principles clashed, the theological and legal. The basic problem was in the question of how to define the relation between the two authorities: the Holy Scripture and the Church. The schism from 1378 and general inquiry about the principles in the instances of ecclesiastical power aroused a renewed interest in this problem. Nevertheless, in the thought of some significant council fathers, the principle appeared that auctoritas ecclesiae should serve as a guarantee of the proper interpretation of the Bible. Besides the ambiguity between the two evidential principles (legal and theological), the core of the dispute between Hus and the council fathers lay precisely in this ecclesiological problem. A significant role in the legal course of Hus’ process was analogically played also by the question of the infallibility of the council. and Sebastián Provvidente.