Strahovská knihovna Královské kanonie premonstrátů Praha CZ AA XIV 9 adl. 15, Národní knihovna ČR Praha CZ 52 C 15 adl. 18, Vědecká knihovna v Olomouci Olomouc CZ 23.891, and BCBT37144
Královská kanonie premonstrátů na Strahově - Strahovská knihovna Praha CZ BR V 42 adl. num. 49, Královská kanonie premonstrátů na Strahově - Strahovská knihovna Praha CZ BU II 128 adl. num. 2, Národní knihovna ČR Praha CZ 34 D 367, Klášter dominikánů - knihovna Praha CZ E VI 111 adl. 1, Klášter Rytířského řádu křižovníků s červenou hvězdou - knihovna Praha CZ XVI H 10 adl. num. 2, Klášter Rytířského řádu křižovníků s červenou hvězdou - knihovna Praha CZ XVI H 8 adl. num. 24, CZ Praha Metropolitní kapitula u sv. Víta v Praze C.d.B.45 adl. 1, and BCBT31830
Maghemite (γ-Fe2O3) nanoparticles, 12 nm in size, were prepared by co-precipitation of Fe(II) and Fe(III) chlorides with ammonium hydroxide and oxidation with hydrogen peroxide. To achieve stability and biocompatibility, obtained particles were coated with silica, to which glucose and ascorbic acid were bound by different mechanisms. The composite particles were thoroughly characterized by transmission electron microscopy, dynamic light scattering, elemental analysis, and FT-Raman and fluorescence spectroscopy to determine composition, morphology, size and its distribution, ζ-potential, and scavenging of peroxyl and hydroxyl radicals. As the particles showed promising antioxidative properties, they may have a possible application as a stable magnetically controlled scavenger of reactive oxygen species., M. Moskvin, D. Horák., and Obsahuje bibliografii
Thyroid hormones are powerful modulators of heart function and susceptibility to arrhythmias via both genomic and non-genomic actions. We aimed to explore expression of electrical coupling protein connexin-43 (Cx43) in the heart of rats with altered thyroid status and impact of omega-3 polyunsaturated fatty acids (omega-3) supplementation. Adult male Lewis rats were divided into following six groups: euthyroid controls, hyperthyroid (treated with T3) and hypothyroid (treated with methimazol) with or without six-weeks lasting supplementation with omega-3 (20 mg/100 g/day). Left and right ventricles, septum and atria were used for immunoblotting of Cx43 and protein kinase C (PKC). Total expression of Cx43 and its phosphorylated forms were significantly increased in all heart regions of hypothyroid rats compared to euthyroid controls. In contrast, the total levels of Cx43 and its functional phosphorylated forms were decreased in atria and left ventricle of hyperthyroid rats. In parallel, the expression of PKC epsilon that phosphorylates Cx43, at serine 368, was increased in hypothyroid but decreased in hyperthyroid rat hearts. Omega-3 intake did not significantly affect either Cx43 or PKC epsilon alterations. In conclusion, there is an inverse relationship between expression of cardiac Cx43 and the levels of circulating thyroid hormones. It appears that increased propensity of hyperthyroid while decreased of hypothyroid individuals to malignant arrhythmias may be in part attributed to the changes in myocardial Cx43., B. Szeiffová Bačová, T. Egan Beňová, C. Viczenczová, T. Soukup, H. Rauchová, S. Pavelka, V. Knezl, M. Barančík, N. Tribulová., and Obsahuje bibliografii