The incidence of venous thromboembolism (VTE ) during childhood is low with two peaks – neonatal and adolescent age. This retrospective study is focused on clinical characteristics of VTE during adolescence. The main goals are to assess the most frequent inherited and acquired risk factors and to evaluate the benefit of D-dimers in diagnostics of venous thromboemblism. The data of 18 adolescents were analysed – 16 girls (88.9%), 2 boys (11.1%). In 9 patients (50%) thrombosis of the lower limb deep veins was diagnosed, six patients (33.3%) suffered from symptomatic pulmonary embolism (PE ) and 3 patients (16.7%) from thrombosis at unusual sites. One patient had an idiopathic VTE , the mean number of the inherited and acquired risk factors was 2.6. The most frequent inherited risk factor was Leiden mutation of factor V (27.8%). The most frequent acquired risk factor was oral contraception (OC ) in 12 out of 16 girls (75%). All of our patients on oral contraception had one or more additional risk factors. 10 out of 18 (55.6%) patients with VTE had elevated activity of factor VIII . The sensitivit, Aneta Samková, Kateřina Lejhancová, Jiří Hak, Antonín Lukeš, and Literatura 22
1., 2, Die Prüfung von Zuckerrübensorten in Mähren im Jahre 1922, Vergleichende Versuche über verschiedene Zuckerrübenstandweite in Mähren im Jahre 1922, Fr. Chmelař, Jar. Šimon und Fr. Mikolášek, and Sonder-Abdruck aus der "Zeitschrift für die Zuckerindustrie der čsl. Republik", Jahrg. XLVII. (IV) 1922/23, Heft 20-21, S. 270-287 u. Heft 48 S. 671-677, Heft 49 S. 683-694, Heft 50 S. 695-703 und Heft 51 S. 707-710