Habitat use of introduced pumpkinseed Lepomis gibbosus in small European streams has received little study despite the species’ potential associations to native fauna of conservation and angling amenity, e.g. brook lamprey Lampetra planeri, European bullhead Cottus gobio, brown trout Salmo trutta. We examined body size, relative body condition, habitat use and species-species associations of pumpkinseed with accompanying fishes in two small streams in southern England during August 2001. Pumpkinseed body condition decreased with pumpkinseed density; the latter correlated with % clay and % riparian grasses in fish 92 mm FL. Most pumpkinseed size classes occurred more often than expected in stretches with conspecifics and with brown trout >300 mm FL; densities of the latter did not correlate with any habitat variables. Indeed, correlations between trout densities and habitat variables were observed mainly in smaller size classes. Habitat associations in other species corresponded to known levels of rheophily; substratum, channel slope, channel width and riparian trees were also important habitat variables. Pumpkinseed dispersal and establishment under conditions of climatic change, which could have ecological and management ramifications, are discussed.
Basic methods of the sensitivity analysis applicable in combination with numerical Monte Carlo type simulation methods are presented in the paper. An example of the influence of a plane steel fame initial imperfections on its load-carrying capacity variability is given there. It is shown in this paper that basic sensitivity analysis methods can be inaccurate in some cases. The updated modification of the procedures mentioned is proposed so that it were possible to apply them to the most various structure types solved by means of simulation methods. The influence of initial imperfections on the load-carrying capacity of steel plane frame is analysed by auxiliary sensitivity analysis. The realisations of input random quantities were simulated by the Latin Hypercube Sampling method. The load-carrying capacity was solved by geometrically and materially nonlinear solution. and Obsahuje seznam literatury
Unilateral otosclerosis combined with avascular necrosis of stapes crura is a rare entity. It should be considered in a case of high grade otosclerosis. Symptoms are the same as in patients who suffer from common otosclerosis. Patients complain on progressive hearing loss and tinnitus. The diagnosis is made clinically by conventional audiologic evaluation and radiologically by x-ray mastoid Schuller's view and CT scan. HRCT scan makes visible all parts of ossicular chain and gives surgeon some information about ossicular chain damage. Surgery with stapedotomy and stapes prosthesis implantation in a case of otosclerosis with avascular necrosis of stapes crura can be success therapy to improve patient's hearing and M. Erdoglija, J. Sotirovic, V. Jacimovic, B. Vukomanovic
63letý pacient, hypertonik, celoživotní kuřák, byl na kliniku TRN FN Plzeň přijat pro tumor pravé plíce zjištěný pro bolesti v pravém hemitoraxu. Na základě stážování byla stanovena diagnóza adenokarcinomu pravé plíce s generalizací do obou plic a levé nadledviny, st. IV. Byla zahájena chemoterapie Paclitaxel (200 mg/m2) – Carboplatina (AUC) – Avastin (15 mg/kg) v rámci studie SAIL firmy Roche s velmi dobrou tolerancí. Po 3. cyklu chemoterapie byla potvrzena parciální remise dle CT hrudníku, dále pokračováno ve stejném schématu chemoterapie s Avastinem do 6. cyklu. Kontrolní CT hrudníku prokázalo další regresi tumoru. Vzhledem k velmi dobrému efektu podávané léčby bylo dále pokračováno v monoterapii Avastinem v třítýdenních intervalech zatím do 22 cyklů. Po 22 měsících léčby s Avastinem bylo dosaženo trvající parciální remise nálezu dle PET/CT trupu, pacient je klinicky zcela bez potíží, neomezen v běžném životě, tedy s velmi dobrou kvalitou života (KS 90 bodů), bez vedlejších nežádoucích účinků Avastinu. Chemoterapie již nemá potenciál pro další prodlužování přežití, je tedy potřebné hledání nových léčebných strategií. Avastin jako inhibitor angiogeneze vede poprvé k prodloužení celkového přežití nad 12 měsíců. Významné prodloužení přežití bez progrese onemocnění (PFS) umožňuje delší přežití bez zhoršení symptomů., A 63-year-old hypertensive patient, a life-long smoker, presented to the Department of Tuberculosis and Respiratory Disease of the Plzeň Teaching Hospital with a right-lung tumour detected due to pain in the right hemithorax. Based on staging, a diagnosis of stage IV right lung adenocarcinoma with generalization into both lungs and the left adrenal gland was made. Chemotherapy with Paclitaxel (200 mg/m2) – Carboplatin (AUC) – Avastin (15 mg/kg) was initiated within the SAIL study of the Roche company with very good tolerance. Following the third chemotherapy cycle, partial remission was confirmed based on CT of the chest; the same chemotherapy regimen with Avastin was continued for six cycles. Follow-up CT of the chest revealed further tumour regression. Given the very good effect of the treatment administered, monotherapy with Avastin was continued in three-week intervals for 22 cycles so far. Following 22 months of Avastin treatment, sustained partial remission was achieved according to PET/CT of the trunk; the patient is clinically free of complaints, without limitations in everyday life, thus with a very good quality of life (KS of 90) and free of adverse effects of Avastin. Chemotherapy has no more potential for further extension of survival; therefore, new therapeutic strategies have to be looked for. As an angiogenesis inhibitor, Avastin leads to an extension of overall survival beyond 12 months. A significant extension of progression-free survival (PFS) enables longer survival without deterioration of symptoms., Radka Bittenglová, Miloš Pešek, and Lit.: 2
In this paper, we prove and discuss averaging results for ordinary differential equations perturbed by a small parameter. The conditions we assume on the right-hand sides of the equations under which our averaging results are stated are more general than those considered in the literature. Indeed, often it is assumed that the right-hand sides of the equations are uniformly bounded and a Lipschitz condition is imposed on them. Sometimes this last condition is relaxed to the uniform continuity in the second variable uniformly with respect to the first one. In our results, we assume only that the right-hand sides of the equations are bounded by some locally Lebesgue integrable functions with the property that their indefinite integrals satisfy a Lipschitz-type condition. Also, we consider that they are only continuous in the second variable uniformly with respect to the first one.
This paper examines the possibility and the desirability of axiomatization in law. In the first part, the paper examines the notion of axiom and the ways how it was or could be introduced into law. It is here where the authors openly invite the reader to lose the conventional approach and think about alternative ways to build basic legal concepts. In the second part, the paper continues by presenting several theories which endeavored (or appeared to endeavor) to show that law can (and should be) axiomatized and which even attempted to axiomatize it. After establishing whether these theories were successful at all, the authors add some of their own ideas on the topic of axiomatization., Martin Madej, Filip Horák., and Obsahuje bibliografické odkazy
We study axisymmetric solutions to the Navier-Stokes equations in the whole three-dimensional space. We find conditions on the radial and angular components of the velocity field which are sufficient for proving the regularity of weak solutions.