Presented work concerns with a sensitivity analysis of a harmonically excited bending vibration of a rotating couple of blades with a friction element with regard to the parameters of the friction characteristic. Either of the blades is discretized by FEM using beam elements and continuously distributed weight is concentrated in nodal points. The friction in central contact points between blade shrouds and the friction element is approximated by a continuous function depending on slip velocities of the shrouds relative to the friction element. Considered friction characteristic respects the micro-slip phase at the very low slip velocities and the macro-slip (full-slip) phase at the higher slip velocities. The values of the friction characteristic parameters are identified by comparison of the numerical simulations of a transient vibration with experiments used in IT AS CR. and Obsahuje seznam literatury
Gaits is one of the splendid functions, which concerns every human being. The standard gait is perceived as precisely controlled activities, based on the periodically coordinated, recurrent leg and trunk (torso) movements, which provide the relocation of the human body from one place to another with the minimal waste energy (Gage J.R., DeLuca P.A., Renshaw T.S. - gait definition) [2]. Different types of diseases cause the changes in gait pattern of the parients. The patients, who have the certain diseases since they were born and the acquired diseases have different deviations from the gait pattern. The conclusion is that there is no universal gait pattern.
The gait of the patients with implants differs from the gait pattern and in this case it depends on the implants type. Analysis and estimation of the gait of the people who have implants is problematic, that is why the paper presents the research connected with the gait diagnostics for people with implants.
Water is one of the most important components of the environment, having a direct effect on the maintenance of life on the Earth. In this paper, analysis of groundwater level variations, water balance and all the parameters included in these quantities, i.e. precipitation, evapotranspiration, surface run-off and subsurface run-off, were performed in the area of the Sudety Mountains for the period of November 2002 - October 2015. The groundwater level variations were computed on the basis of the mean Terrestrial Water Storage (TWS) values determined from Gravity Recovery and Climate Experiment (GRACE) observations and Global Land Data Assimilation System (GLD AS). TWS data have been determined with a spatial resolution of one degree and temporal resolution of one month. According to the results, groundwater level variation can be approximately determined by water balance changes (with reverse sign). Specifically, for the Sudety area a high average stability of total water storage over the period of past 13 years and decline in groundwater level by about 13 cm (approximately 1 cm/year) was detected., Zofia Rzepecka, Monika Birylo, Joanna Kuczynska-Siehien, Jolanta Nastula and Katarzyna Pajak., and Obsahuje bibliografické odkazy
In the paper an analysis of the influence of physical conditions inside the interelectrode gap (IEG) on the workpiece (WP) shape evolution has been presented. This problem has been solved on the basis of a two-dimensional model of an electrolyte and hydrogen mixture flow through the interelectrode gap (IEG). There has also been demonstrated general mathematical modeling algorithm as well as a numerical calculation scheme. and Obsahuje seznam literatury
The potential role of intestinal intraepithelial lymphocytes (i-IELs) in the generation of host protective immunity after helminth infection was investigated using the Trichinella spiralis (Owen, 1835)/mouse model. In this study we found a significant rise of TCRyô i-IELs (P < 0.001) concurrent with the jejunal goblet cells (GC) hyperplasia in T. spiralis-infected C57BL mice on day 4 p.i. However, no direct relationship between the kinetics of the increase in TCRy5+ i-IELs and T, spiralis expulsion was observed in infected mice. Taken together, these results implicate that γδ i-IELs probably perform a unique functions related to the regulation of the CiC proliferation accompanying T. spiralis gut infection. As is known, these TCRyS* i-IELs may release mediators or growth factors that in turn influence GC differentiation. With the use of dexamethason (DEX), a potent anti-inflammatory agent which also induces apoplotic ceil death in i-IELs, wc have confirmed that the expulsion of T. spiralis from the mouse gut is accompanied by an inflammatory response. Indeed, the GC are clearly involved in these phenomena, apparently under the regulation by TCRy8+ i-lEL-mediated responses, since DEX abrogated GC proliferation in T. spiralis-infected C57BL mice and subsequently augmented adult worm burden. Our data also show that the rejection of adult worms starts concurrently with a significant increase in TCRaß* and CDS* i-IELs (P < 0.05 and P < 0.01, respectively), namely by day 7 p.i. At the same time, CD4* cells significantly decreased (P < 0.05) in the intestinal epithelium of T. spira/ir-infected, ví uninfected mice. These results may indicate that the TCRaß4 and CDS* i-IELs act as effectors of anti-7’, spiralis defence reactions. The implications of these findings for the potential role of intestinal intraepithélial CD8 and TCRaß' cells in the pathogenesis of the intestinal lesions during T. spiralis gut infection are discussed.
The sequences of 10 conservative regions (CR) of minicircles of 6 selected isolates of freshwater fish try-panosomes have typical organization of this region with high degree of sequence conservation. The comparison with CRs of other trypanosomatids showed that freshwater fish trypanosomes represent a compact separate group within the genus Trypanosoma. The alignment of all sequences obtained revealed, however, the existence of 2 types of CRs in sequenced minicirclcs, with the differences concentrated in a short region. Taxonomic consequences of these results arc discussed.
This article aims to share the results of research conducted in the Fergana chemical plant of furan compounds (FCPFC) in Uzbekistan.19 workers of the Furan compounds plant, in Fergana, Uzbekistan, were tested. By neutron activation analysis method, we have studied microelement composition of saliva, blood, dental hard tissue, and the level of Ca, Zn, Fe, and Ag in these subjects. We have detected that the level of chemical elements in dental hard tissue, blood, and saliva of these workers was subject to negative changes as compared to the analysis results from those in the control group. The research results have practical value for the prophylaxis, treatment, and health resumption of the people living in rugged ecological environment and workers who are engaged with harmful substances in chemical industry. Furthermore,this research also provides recommendations for treatment of dental diseases related to common conditions of pathophysiological processes carried out by living organisms., Sunnatillo Gaffarov, Salim Sharipov, and Literatura