Number of results to display per page
Search Results
972. Farnost svatého Prokopa ve Vamberku v proměnách staletí /
- Creator:
- Berger, Miroslav
- Type:
- text and monografie
- Subject:
- Křesťanství. Křesťanská církev všeobecně. Eklesiologie, farnosti, kostely, církev katolická, dějiny církevní, přehledná zpracování dějin českých zemí (chronologicky), and církevní a náboženské dějiny
- Language:
- Czech
- Description:
- 70 výt.
- Rights:
- unknown
973. Félicien Rops :
- Creator:
- Půtová, Barbora,
- Publisher:
- Dybbuk,
- Type:
- monografie
- Subject:
- Malířství, Rops, Félicien,, umělci, dekadence, malířství, malíři belgičtí, světové dějiny 1789-1918, Belgie, and dějiny umění, mecenát
- Language:
- Czech
- Description:
- Chronologický přehled
- Rights:
- unknown
974. Fenomén "katolická teologie" /
- Creator:
- Torrell, Jean-Pierre,
- Publisher:
- Krystal OP,
- Type:
- monografie
- Subject:
- Křesťanská teologie. Dogmatická teologie, teologie katolická, dějiny teologie, přehledná zpracování světových dějin (chronologicky), and teologie, ikonografie, zbožnost, hagiografie
- Language:
- Czech
- Rights:
- unknown
975. Fenomén eucharistie :
- Creator:
- Chadima, Martin,
- Publisher:
- Ritas,
- Type:
- studie
- Subject:
- Křesťanská teologie. Dogmatická teologie, eucharistie, teologie husitská, teologie křesťanská, dogmatika křesťanská, přehledná zpracování dějin českých zemí (chronologicky), and teologie, ikonografie, zbožnost, hagiografie
- Rights:
- unknown
976. Fenomén Vatikán :
- Creator:
- Halas, František X.,
- Type:
- text and monografie
- Subject:
- Křesťanství. Křesťanská církev všeobecně. Eklesiologie, papežství, vztahy náboženství-politika, vztahy stát-církev, politika zahraniční, diplomacie církevní, vztahy Čechy-papežství, vztahy česko-vatikánské, Vatikán, přehledná zpracování světových dějin (chronologicky), papežství, církevní politika, politické dějiny, politici, přehledná zpracování dějin českých zemí (chronologicky), and zahraniční politika, mezinárodní vztahy
- Language:
- Czech
- Description:
- Chronologický přehled and Terminologický slovník
- Rights:
- unknown
977. Ferdinand Peroutka pro Svobodnou Evropu :
- Creator:
- Peroutka, Ferdinand,
- Publisher:
- Radioservis,
- Type:
- komentáře
- Subject:
- Politika, Peroutka, Ferdinand,, Svobodná Evropa, rozhlas, komentáře rozhlasové, opozice protikomunistická, Československo 1948-1969, televize, rozhlas, and odboj, odpor, antifašismus, antikomunismus
- Rights:
- unknown
978. Fetal parotid gland structural remodeling in case of intrauterine growth retardation
- Creator:
- Morozov, Sergiy and Reshetnikova, Olga
- Format:
- braille, electronic resource, remote, and elektronický zdroj
- Type:
- model:article, article, Text, statistics, and TEXT
- Subject:
- parotis--abnormality--anatomie a histologie--patologie--růst a vývoj, růstová retardace plodu, indukovaný potrat, plod, pitva, lidé, and stereometric study
- Language:
- English
- Description:
- The important biological role of saliva in maintaining of the homeostasis of the oral cavity environment, preventing infection and tooth decay is widely accepted. Salivary glands insufficiency may violate the balance between health and disease. Clinical data indicated that the destruction, agenesis and aplasia of salivary gland commonly followed with hypo salivation, low salivary flow, which resulted in severe caries and periodontal disease. Salivary gland dysfunction also frequently found in preterm and low birth weight newborns. But the information about structural background of abnormal salivation in early childhood is still limited. A presence of any correlation between salivary glands structural development and intrauterine restrictions of fetal growth (IUGR) is unclear. The aim of present study was to determine morphological and morphometric peculiarities of human parotid gland in case of IUGR at late gestation. Material and methods: Parotid glands of twenty human fetuses 2022 weeks of gestation with diagnosed IUGR from late abortions material were compared with ten fetal glands in cases of induced abortions due to psychological reasons (control group). Tissue samples were immersionfixed in 10% buffered formalin solution, embedded in paraffin wax. Histological slides were stained routinely with hematoxylin & eosin, with Van Gieson's Stain. Microscopical examination was performed on magnification x 40 and x 100. Stereometric study by point count method at magnification x 40 allowed finding out volume fractions (VF) of glands parenchyma and stroma. VF of lobules components (glands wall, glands lumen, ducts wall, ducts lumen, vessels, intralobular connective tissue) were registered at magnification x100. Morphometry of the secretory portion of the parotid gland was conducted on the Zeiss microscope with the help of the AxioVision Rel.4.8 program. The mature (differentiated) end pieces were measured, including their area (in mkm2), width, height, perimeter (all in mkm). Similar measurements were done in the foci of immature secretory ends of a gland. Additionally the mean height of the epithelial cells layer within the mature secretory end pieces was measured. The differences were analyzed by methods of mathematical statistics using the software Microsoft Excel; data was compared with control measurements by Students ttest. Results: The results of present research have shown the delayed differentiation of fetal parotid glands parenchymal components in case of IUGR. The parenchymal VF did not reach control values. Furthermore, VF of lobules components was also decreased. Ducts lumens appeared to be significantly narrower than at physiological gestation. Interlobular and intralobular connective tissue stroma, in contrast to the controls, occupied vast areas, and their volume fraction was increased. Deficit of the parenchymal components of the gland was enhanced by slower maturation of glands. In cases with IUGR, differentiated glands occupied smaller area, with reduced width, height and perimeter. Epithelium lining the differentiated glands is characterized by significantly lower height compared to the control group. Delayed differentiation resulted in higher proportion of immature glands. Their area, width, height and perimeter increased. IUGR was also accompanied with a variety of pathological changes. Conclusion: Present evidences suggest that IUGR leads to impaired growth and maturation of the parotid gland. Structural immaturity and lack of differentiated parenchymal elements of the organ may form the basis of its secretory functions lesion. The finding tends to support the hypothesis that the mechanism behind the increased risk of dental pathology in preterm, low birth weight and retarded children is centred at structural and functional immaturity of salivary gland., Sergiy Morozov, Olga Reshetnikova, and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
979. Fichtovy pragmatické dějiny lidského ducha /
- Creator:
- Vrabec, Martin,
- Publisher:
- Togga ve spolupráci s Fakultou humanitních studií Univerzity Karlovy v Praze,
- Type:
- monografie
- Subject:
- Teorie poznání. Epistemologie, Fichte, Johann Gottlieb,, filozofie německá, myšlení filozofické, Německo, světové dějiny 1648-1789, filozofie, filozofové, and světové dějiny 1789-1918
- Language:
- Czech
- Rights:
- unknown
980. Fifteen years of single center experience with stem cell transplantation for multiple myeloma: a retrospective analysis
- Creator:
- Radocha, Jakub, Maisnar, Vladimír, Zavřelová, Alžběta, Cermanová, Melanie, Lánská, Miriam, Kmoníček, Miloslav, Jebavý, Ladislav, Bláha, Milan, Malý, Jaroslav, and Žák, Pavel
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT
- Subject:
- dospělí, staří, přežití po terapii bez příznaků nemoci, ženské pohlaví, lidé, mužské pohlaví, lidé středního věku, mnohočetný myelom--mortalita--patologie--terapie, retrospektivní studie, transplantace kmenových buněk, přežívající - četnost, and výsledek terapie
- Language:
- English
- Description:
- INTRODUCTION: Autologous stem cell transplantation (ASCT) became standard of care for patients with multiple myeloma (MM) under the age of 65 years. We routinely perform ASCT for newly diagnosed MM since 1996 in our department. PATIENTS AND METHODS: We retrospectively analyzed all 285 transplants in 185 patients done for MM from January 1996 till December 2010. We analyzed overall survival (OS) and progression-free survival (PFS) regarding conditioning, stage, complete or very good partial remission (CR, VGPR) achievement, renal impairment, single vs. double transplant. RESULTS: Estimated 10-years survival of the whole set of patients is 39% (median survival 95 months). Patients with renal impairment show same OS as those without (p = 0.22). Patients show similar overall survival and event free survival regardless of type of transplant. We observed better outcome in terms of overall survival in patients treated with new drugs (p = 0.0014). Reaching CR or VGPR was not translated into better OS (p = 0.30) and EFS (p = 0.10). Also stage of the disease and whether single or double transplant was used did not make any significant difference in the outcome. CONCLUSION: Stem cell transplantation greatly improved outcome of patients with MM. Poor outcome of allogeneic transplantation in our group of patients is related to high transplant related mortality (20% vs. 0%) and unexpected high relapse rate. There is a trend towards better survival, when new drugs are incorporated at any time in the course of the disease. This fact supports hypothesis that use of these drugs with ASCT should translate into better long-term outcome. and J. Radocha, V. Maisnar, A. Zavrelová, M. Cermanová, M. Lánská, M. Kmonícek, L. Jebavý, M. Bláha, J. Malý, P. Zák
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public