Large debris transported by flood affects scour features at bridge piers and increases the risks of structural failure. Geometric characteristics of the debris and the relative position of the pier with respect to the river bank are important parameters for the scour process. The interaction between the water flow and debris accumulation increases the shear stress, turbulence and consequently enhances the scour depth at the pier. This paper aims at analyzing such effects on scour evolution at bridge piers. To this end, two series of tests were carried out under clear water condition with different debris geometries and percentage blockage ratios. Experimental evidences showed that the pier position only influences scour evolution and equilibrium morphology for low water depths. Conversely, its effect becomes negligible for scour at bridge piers with debris accumulation and higher water depths. Useful practical relationships have been derived, with satisfactory prediction capability of the scour evolution for all the tested configurations.