Netušená síla slabých vazeb: Nekovalentní interakce v biodisciplínách

Title:

Netušená síla slabých vazeb: Nekovalentní interakce v biodisciplínách

Creator:

Hobza, Pavel and Havlas, Zdeněk

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:92a4f337-e767-4708-9e28-09a5f9e9530a
uuid:92a4f337-e767-4708-9e28-09a5f9e9530a

Type:

article, model:article, and TEXT

Description:

Intriguing power of weak bonds (Noncovalent interactions in biodisciplines). The role of weak noncovalent interactions in nature, especially in biodisciplines, is demonstrated. First, it is emphasized how strongly properties of the most common solvent and biomedium, water, are influence by noncovalent interactions. Also structure and properties of typical biomolecules, nucleic acids and proteins result from noncovalent interactions, and the important role of dispersion forces in these systems is stressed. The physical origin of the noncovalent interactions is explained. The very important manifestation of the noncovalent interactions in biology, hydrogen bond, is extended to the newly discovered type of hydrogen bond, called improper (blue-shifted) hydrogen bond. Finally, the role of noncovalent interactions in silico drug design is briefly discussed.

Language:

Czech

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Vesmír | 2010 Volume:89 (140) | Number:10

Harvested from:

CDK

Metadata only:

false