Buňky s velkým potenciálem. 1. Historie indukované pluripotence a metody přípravy iPS buněk

Title:

Buňky s velkým potenciálem. 1. Historie indukované pluripotence a metody přípravy iPS buněk
Cells of a great potential. 1. History of induced pluripotency and methods of iPS cell preparation

Creator:

Vodičková Kepková, Kateřina, Petr Vodička, and Jan Motlík

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:c140f6eb-881f-4a84-bcd8-16e131a8a5c8
uuid:c140f6eb-881f-4a84-bcd8-16e131a8a5c8
issn:0044-4812

Subject:

Biologické vědy, buňky, cells, 2, and 57/59

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

Induced pluripotent stem cells (iPSC) are undifferentiated cells capable of unlimited self-renewal. By introducing specific transcription factors, any somatic (fully differentiated) cell of the mammalian body can be changed (reprogrammed) into iPSC. The iPSCs are very similar to embryonic stem cells in their molecular and functional properties. By using specific factors, iPSCs can be differentiated into each of the about 200 cell types in the human body. The big advantage of iPSCs is the availability of somatic cells (isolation from blood or skin biopsy). Creation of "tailor made" iPSCs for each patient would allow transplantation of own cells and avoid problems with finding an immunologically compatible donor. and Kateřina Vodičková Kepková, Petr Vodička, Jan Motlík.

Language:

Czech

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Živa | 2016 Volume:64 (102) | Number:4

Harvested from:

CDK

Metadata only:

false