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Start Over Coverage 233-240

2. Multiglandular parathyroid disease in primary hyperparathyroidism with inconclusive conventional imaging

Creator:
Zajíčková, Kateřina, Včelák, Josef, Lešková, Zuzana, Grega, Marek, Goltzman, David, and Zogala, David
Format:
počítač and online zdroj
Type:
model:article and TEXT
Subject:
multiglandular parathyroid disease, primary hyperparathyroidism, 18F-fluorocholine PET/CT, and persistent primary hyperparathyroidism
Language:
English
Description:
Inconclusive preoperative imaging is a strong predictor of multiglandular parathyroid disease (MGD) in patients with primary hyperparathyroidism (PHPT). MGD was investigated in a cohort of 17 patients with PHPT (mean age 64.9 years, total calcium 2.75 mmol/l and parathyroid hormone (PTH) 113.3 ng/l) who underwent 18F-fluorocholine PET/CT (FCH) imaging before surgery. The initial MIBI SPECT scintigraphy (MIBI) and/or neck ultrasound were not conclusive or did not localize all pathological parathyroid glands, and PHPT persisted after surgery. Sporadic MGD was present in 4 of 17 patients with PHPT (24 %). In 3 of 4 patients with MGD, FCH correctly localized 6 pathological parathyroid glands and surgery was successful. Excised parathyroid glands were smaller (p <0.02) and often hyperplastic in MGD than in single gland disease. In two individuals with MGD, excision of a hyperplastic parathyroid gland led to a false positive decline in intraoperative PTH and/or postoperative serum calcium. Although in one patient it was associated with partial false negativity, parathyroid imaging with FCH seemed to be superior to neck ultrasound and/or MIBI scintigraphy in MGD.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

3. Photosynthesis and chlorophyll fluorescence in two hybrids of sorghum under different nitrogen and water regimes

Creator:
Cechin, I.
Format:
bez média and svazek
Type:
model:article and TEXT
Subject:
drought, intercellular CO2 concentration, leaf water potential, photosystem 2, Sorghum bicolor, stomatal conductance, transpiration rate, and water use efficiency
Language:
Multiple languages
Description:
In two hybrids of sorghum (Sorghum bicolor Moench.), C51 and C42, high nitrogen concentration (HN) increased net photosynthetic rate (PN), stomatal conductance (gs), and transpiration rate (E) of well watered (HW) plants. Water stressing (LW plants) resulted in low PN, gs, and E in both hybrids, but the values were still higher in HN plants as compared to low nitrogen-grown (LN) plants. Intercellular CO2 concentration (Ci) increased in droughted plants. This increase was much higher in LN plants as compared to HN plants. Instantaneous water use efficiency was lower in LN plants as a consequence of a greater effect of water stress on photosynthesis. Leaf water potential was reduced by water stress in all treatments. Analysis of chlorophyll a fluorescence at room temperature showed that photosystem 2 (PS2) was rather tolerant to the water stress imposed. Water stress caused a slight decrease in the efficiency of excitation capture by open PS2 reaction centres (Fv/Fm). The in vivo quantum yield of PS2 photochemistry (ΦPS2) and the photochemical quenching coefficient (qP) were slightly reduced, while the nonphotochemical quenching coefficient (qN) was increased under the water stress. However, in hybrid C42 these characters were little or not affected by the water stress.
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public