Nobel Lecture, presented on December 8, 2016, at Aula Magna, Stockholm University. This article describes the history and background of three discoveries cited in this Nobel Prize: The "TKNN" topological formula for the integer quantum Hall effect found by David Thouless and collaborators, the Chern insulator of quantum anomalous Hall effect, and its role in the later discovery of time-reversal invariant topological insulators, and the unexpected topological spin-liquid state of the spin-1 quantum antiferromagnetic chain, which provided an initial example of topological quantum matter. This article summarizes how these early beginnings have led to the exciting, and currently extremely active, field of "topological matter"., F. Duncan M. Haldane ; přeložil Ivan Gregora ; foto A. Mahmoud, Odile Belmontová., and Obsahuje bibliografii
Nobel Lecture, presented on December 8, 2016, at Aula Magna, Stockholm University. In his lecture F. J. M. Kosterlitz described theoretical discoveries of topological phase transitions and topological phases of matter, partially on behalf of the main researcher behind those discoveries, David Thouless, who was not able to give the talk. First, the history of the collaboration between Kosterlitz and Thouless was briefly described. Then, a summary of their contribution to applications of topology to classical Berezinskii-Kosterlitz-Thouless of BKT phase transition was described., John Michael Kosterlitz ; přeložil Ivan Gregora ; foto A. Mahmoud., and Obsahuje bibliografii
Mikrosvět elementárních částic, atomů a procesů odehrávajících se mezi nimi je plný podivností. Částice může projít naráz dvěma různými štěrbinami, fotony mohou být navzájem provázané na obrovské vzdálenosti, kočka (alespoň ona pověstná Schrödingerova) může být zároveň živá i mrtvá... Může pozoruhodný kvantový svqt dovolit i stav, kdy by nějaká látka bya sočasně pevná a supratekutá? A mohou kvantové supratekuté systémy pomoci osvětlit jeden z posledních nevyřešených problémů klasické fyziky - turoblenci? Vědci, včetně českých, intenzivné hledají odpovědi. and Jana Olivová.
We investigate the Zassenhaus conjecture regarding rational conjugacy of torsion units in integral group rings for certain automorphism groups of simple groups. Recently, many new restrictions on partial augmentations for torsion units of integral group rings have improved the effectiveness of the Luther-Passi method for verifying the Zassenhaus conjecture for certain groups. We prove that the Zassenhaus conjecture is true for the automorphism group of the simple group PSL(2, 11). Additionally we prove that the Prime graph question is true for the automorphism group of the simple group PSL(2, 13)., Joe Gildea., and Obsahuje seznam literatury
The objective of our study was to assess the influence of mechanical ventilation on healthy body organs. Fifteen piglets (aged 6 weeks, 19-27 kg) were anesthetized, instrumented, and divided into three groups: Group A - spontaneously breathing, group B - mechanically ventilated with tidal volume 6 ml/kg, and group C - ventilated with tidal volume 10 ml/kg for 12 hours. The parameters of lung, heart, liver and kidney functions neurohumoral regulation and systemic inflammatory reaction were recorded initially (time-1) and after 12 hours (time-12) of mechanical ventilation. At the onset of experiment (time-1) the levels of soluble adhesive molecules were higher (CAM; P<0.01), glomerular filtration index and free water clearance were lower (P<0.05) in both ventilated groups than in group A. Right ventricle myocardial performance index was higher (RIMP; P<0.05) in group C when compared with group A. Levels of CAM (P<0.05) and creatinine clearance (P<0.01) were higher, free water clearance was lower (P<0.05) in group C when compared to group B. At time-12 the RIMP (P<0.05) and levels of CAM were increased (P<0.01), creatinine clearance was decreased (P<0.05) in both ventilated groups compared to the same parameter at time-1. Ventilation index was higher (P<0.05), and hypoxemic index was lower (P<0.01) in group C when compared to group B. In conclusion, this study showed that mechanical ventilation induced changes compatible with early inflammatory response in healthy animals. Higher tidal volumes had detrimental effect on ventilatory parameters, reduced myocardial performance and potentiated adverse reaction of other organs., J. Kobr ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
The present study investigated cardiac function in hearts of mice with total deficiency of the β1-, β2- and β3-adrenoceptors (TKO) in comparison to wildtype mice (WT). We investigated cardiac morphology and echocardiographic function, measured protein expression of Ca2+-regulatory proteins, SERCA 2a activity, myofibrillar function, and performed running wheel tests. Heart weight and heart-to-body weight ratio were significantly smaller in TKO as compared to WT. This was accompanied by a decrease in the size of the cardiomyocytes in TKO. Heart rate and ejection fraction were significantly diminished in TKO as compared to WT. Protein expressions of SERCA 2a, ryanodine receptor and Na+/Ca2+-exchanger were similar in TKO and WT mice, but phospholamban protein expression was increased. PKAdependent phosphorylation of phospholamban at serine 16 was absent and CaMKII-dependent phosphorylation at threonine 17 was decreased in TKO. All alterations were paralleled by a decrease in SERCA 2a-activity. A similar maximal calciumdependent tension but an increased myofibrillar calciumsensitivity was measured in TKO as compared to WT. We did not observe relevant functional impairments of TKO in running wheel tests. In the absence of β-agonistic stimulation, SERCA 2a activity is mainly regulated by alterations of phospholamban expression and phosphorylation. The decreased SERCA 2a activity following β-adrenoceptor deficiency may be partly compensated by an increased myofibrillar calcium-sensitivity., S. Lee ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy