Hemolytic uremic syndrome (HUS) is a type of thrombotic microangiopathy, in the course of which some patients may develop chronic kidney disease (CKD). It is clinically important to investigate the markers of a poor prognosis. The levels of angiotensinogen (AGT) and interleukin-18 (IL-18) in serum and urine were evaluated. Study was conducted in 29 children with a history of HUS. Serum and urine AGT concentration was significantly higher in children after HUS as compared to the control group. No differences depending on the type of HUS and gender were noted. The serum concentration of IL-18 in children after HUS was significantly lower, whereas in urine did not differ significantly between the sick and healthy children. A negative correlation between the concentration of AGT in serum and albuminuria in patients after HUS was detected. The results indicate that the concentration of AGT in serum and urine in children after HUS increases, which may indicate the activation of the intrarenal renin-angiotensin-aldosterone system. The statement, that AGT may be a good biomarker of CKD after acute kidney injury due to HUS requires prospective studies with follow-up from the acute phase of the disease on a larger group of patients. Reduced IL-18 serum concentration in children after HUS with no difference in its urine concentration may indicate a loss of the protective effects of this cytokine on renal function due to previously occurred HUS., K. Lipiec, P. Adamczyk, E. Świętochowska, K. Ziora, M. Szczepańska., and Obsahuje bibliografii
The study deals with Anglophone and francophone identities in Africa on the example of Cameroon. In contemporary Africa, though quite hidden, one may encounter two ways of how both identities come into latent or open conflict. Language policies in Africa still show an inevitable impact and heritage of colonial past when European languages entered the African linguistic, political, social and cultural arenas causing further problems expecially in multi-ethnic societies or in states which came to existence by a junctiona of two different entities. This is exactly the case of Cameroon., Jan Záhořík., and Obsahuje bibliografii
This review compiles information on the taxonomy, identification, geographical distribution, life cycles, host ranges, occurrence, development and growth in both intermediate and final hosts, pathogenicity, and control measures of AnguilUcola crassus and A. globiceps, swimbladder nematodes of farmed and wild populations of two species of eels, Anguilla japonica and A. anguilla, in East Asia. Anguillicola crassus is distributed in Japan, Korea, Taiwan, and China, while A. globiceps is reported only in Japan and China. These nematodes use cyclopoid copepods as intermediate hosts. Known intermediate hosts are Eucyclops serrulatus (Japan) and Therirwcyclops hyalinus (Korea) for A. crassus, and Mesocyclops leuckarti, T. hyalinus, T. taihokuensis, E. serrulatus, Acanthocyclops viridis, and Cyclops slrenuus (China) for A. globiceps. Anguillicola crassus shows a seasonal occurrence in T. hyalinus with high prevalence in summer, Paratenic hosts are yet unknown in East Asia. Anguillicola crassus is relatively common in farmed and wild populations of Anguilla japonica in East Asia, but A. globiceps is usually found in wild populations of A. japonica in Japan and China. In culture ponds, A. crassus is more prevalent and abundant in A. anguilla than in A. japonica. Although A. globiceps induces only the thickening of the host’s swimbladder wall, A. crassus gives severe pathological effects in A. anguilla and heavy infection leads to host mortality. Prevalence of A. crassus in A. japonica cultured in Japan and Korea is relatively low in winter, whereas prevalence of A. globiceps in wild populations of A. japonica from Japan is high in winter.