Within the frame of the mass discretisation method has been designed the mathematical - physical model of the pseudoplanetary system of seven degrees of freedom for the analysis of the influence of the number of satellites and for free or elastic mounting of the sun wheel as a next phase of the solution of general differential system with branched - split power flow.
Previous observation demonstrated that measured nucleolar and nuclear diameters and the resulting calculated ratio might facilitate estimation of the approximate size of the nuclear region occupied by the nucleolar bodies. The size of nuclear regions occupied by nucleolar bodies decreased during the differentiation and maturation of leukaemic lymphocytes, but was constant for each differentiation or maturation stage. The present study was
unde-taken to provide more information on the approximate size of the nuclear regions occupied by nucleolar bodies in leukaemic granulocytic progenitors. Myeloblasts of established Kasumi 1 and K 562 cell lineages originating from human myeloid leukaemias were convenient models for such study because they represented only one and early differentiation stage of granulocytic progenitors. According to the results, the maximal and mean nucleolar body : maximal and mean nuclear diameter ratios in myeloblasts without heavy nuclear alterations were stable and not markedly influenced by the anti-leukaemic treatment or aging. Thus, the roughly estimated size of nuclear regions occupied by nucleolar bodies in these cells appeared to be similar and stable regardless of aging or antileukaemic treatment. In contrast, the antileukaemic treatment or aging in such myeloblasts induced marked reduction of the nucleolar biosynthetic activity reflected by the decreased number of nucleolar fibrillar centres. and Corresponding author: Karel Smetana
A new application of the parametric anti-resonance is discussed. This phenomenon can be used not only for suppressing self-excited vibration or to reduce the externally excited vibration but also to suppressing self-excited vibration or to reduce the externally excited vibration but also to suppress the parametric resonance when certain conditions are met. Another aim is to stimulate further investigations and the practical applications. and Obsahuje seznam literatury
The aim of this contribution is to present a basic survey of publications dealing with the means of vibration suppression in several kinds of self-excitation. The attention is given to passive and active means using parametric excitation. A special attention is given to the latter and the necessary steps for answering important questions are formulated to initiate further investigation and especially application to real systems. and Obsahuje seznam literatury
Smoking is the most important cardiovascular (CV) risk factor. Stopping smoking halves the CV risk. Every clinician should provide a brief intervention with smokers. Intensive treatment should be available to those who need it. There are 37 Centers for Tobacco Dependence in the Czech Republic, which offer treatment including a psychobehavioral intervention and pharmacotherapy (varenicline, nicotine, bupropion). Czech physicians, pharmacists and nurses are regularly educated about smoking cessation. We describe the results of intensive treatment offered by our centers. Treatment includes screening (1 h), an intervention (2 h), and follow-up visits during the next 12 months. Among 3532 patients, 34.3 % had CO-validated abstinence at 12-months (including 489 patients who attended the screening visit + only the 12-month follow up visit). Among patients who underwent the intervention, the abstinence rate was 38.2 %. The majority of patients who underwent the intervention (N=2470) used some form of pharmacotherapy. After one year, the abstinence rate was 43.4 %, compared to 15.9 % (N=573) without pharmacotherapy. Only 28 % of patients came on the recommendation of a physician. Despite the decrease in CV risk following smoking cessation and the effectiveness of treatment, centers are underutilized., E. Králíková, A. Kmeťová, L. Štěpánková, K. Zvolská, V. Felbrová, S. Kulovaná, Z. Bortlíček, M. Blaha, K. Fraser., and Obsahuje bibliografii