Ještě nedávno se tuková tkáň považovala za pouhou zásobarnu energie a symbol nežádoucí obezity, která má značný podíl na tzv. civilizačních chorobách. Stále víc vědeckých poznatků však začalo podobně jednostranný pohled nabouravat a ukazovat, že tuková tkáň není zbytečné zlo, ale má mnoho důležitých funkcí, bez nichž by se naše tělo neobešlo. and Jana Olivová, Stanislava Kyselová.
Článek přináší zprávu o pozorování nového invazivního druhu motýla - zavíječe zimostrázového (Cydalima perspectalis) na zimostrázu vždyzeleném (Buxus sempervirens) v Břeclavi v létě 2015. Druh se rozšířil z východní Asie, první výskyt v Evropě je doložen r. 2006 z Německa, v ČR byl první nález publikován r. 2011 z Hnanic na Znojemsku (v r. 2015 je potvrzen výskyt i z Prahy). Housenky jsou schopné způsobit značné škody zvláště vzhledem k tomu, že poškození zpočátku spíše působí jako přirozeně proschlé větvičky. Až při bližší prohlídce je vidět často velké množství housenek hlouběji v keřích. Zavíječ zimostrázový nemá v Evropě přirozené nepřátele. Jako ochranu lze použít kontaktní insekticidy, které však likvidují i jiné, užitečné druhy hmyzu, nebo ekologicky šetrnější preparáty s toxinem bakterie Bacillus thuringiensis. V malých výsadbách lze housenky likvidovat také ručně., In the summer of 2015, a new invasive species - Box Tree Moth (Cydalima perspectalis) - was observed in Břeclav on Common Box (Buxus sempervirens). The moth spread from East Asia, the first presence in Europe was documented in Germany (2006), the first published occurrence in the Czech Republic is from the Znojmo region (2011; in 2015 confirmed in Prague). The caterpillars can cause considerable damage especially due to the fact that the damage initially tends to look like naturally dry twigs. Nevertheless, upon closer inspection, a large number of caterpillars are often seen deeper in the bushes. Box Tree Moth has no natural enemies in Europe. As a protection, contact insecticides may be used which, however, kill other useful insects too, or environmentally friendly formulations of Bacillus thuringiensis toxin. In small plantings caterpillars can also be disposed of by hand., and Zdeněk Hubálek, Jana Grulichová.
Metabolic syndrome is a prevalent, complex condition. The search for genetic determinants of the syndrome is currently undergoing a paradigm enhancement by adding systems genetics approaches to association studies. We summarize the current evidence on relations between an emergent new candidate, zinc finger and BTB domain containing 16 (ZBTB16) transcription factor and the major components constituting the metabolic syndrome. Information stemming from studies on experimental models with altered Zbtb16 expression clearly shows its effect on adipogenesis, cardiac hypertrophy and fibrosis, lipid levels and insulin sensitivity. Based on current evidence, we provide a network view of relations between ZBTB16 and hallmarks of metabolic syndrome in order to elucidate the potential functional links involving the ZBTB16 node. Many of the identified genes interconnecting ZBTB16 with all or most metabolic syndrome components are linked to immune function, inflammation or oxidative stress. In summary, ZBTB16 represents a promising pleiotropic candidate node for metabolic syndrome., O. Šeda, L. Šedová, J. Včelák, M. Vaňková, F. Liška, B. Bendlová., and Obsahuje bibliografii
The data derived from rat models and the preliminary results of human studies provide strong indices of involvement of common ZBTB16 variants in a range of cardiovascular and metabolic traits. This cross-sectional study in the Caucasian cohort of 1517 Czech adults aimed to verify the hypothesis that ZBTB16 gene variation directly affects obesity and serum lipid levels. Genotyping of nine polymorphisms of the ZBTB16 gene (rs11214863, rs593731, rs763857, rs2846027, rs681200, rs686989, rs661223, rs675044, rs567057) was performed. A multivariate bidirectional regression with the reduction of dimensionality (O2PLS model) revealed relationships between basal lipid levels and anthropometric parameters and some minor ZBTB16 alleles. In men, the predictors - age and presence of minor ZBTB16 alleles of rs686989, rs661223, rs675044, rs567057 - were associated with significantly higher body mass index, waist to hip ratio, body adiposity index, waist and abdominal circumferences, higher total cholesterol and LDL cholesterol and explained 20 % of variability of these variables. In women, the predictors - age and presence of the rs686989 minor T allele - were also associated with increased anthropometric parameters and total cholesterol and LDL cholesterol but the obtained O2PLS model explained only 7.8 % of the variability of the explained variables. Our study confirmed that the selected gene variants of the transcription factor ZBTB16 influence the obesity-related parameters and lipid levels. This effect was more pronounced in men., B. Bendlová, M. Vaňková, M. Hill, G. Vacínová, P. Lukášová, D. Vejražková, L. Šedová, O. Šeda, J. Včelák., and Obsahuje bibliografii
The trans-border area of the Sudetes between Žďarky and Pstrążna has attracted Prussian/German, Austrian, Czech and Polish geologists since the middle of the 19th century. The history of mapping of this area reflects the scientific development of geological centres in Berlin, Vienna, Prague and Wrocław. This paper presents a description of the oldest geological maps of Lower Silesia in the context of changing knowledge on the Carboniferous and Cretaceous stratigraphy and on the tectonics of the region. On the basis of DEM and field studies the author presents his own geological map of the area of the Pstrążna Elevation together with a description of the local structural geology. A regional structural model is suggested, that explains all the local elevations as having developed in response to a dextral strike-slip activity of the Žďarky-Jakubowice Fault during late Tertiary to Recent times, at an eastern extension of the Poříčí-Hronov Fault Zone., Jurand Wojewoda., and Obsahuje bibliografii
Forty years ago, the first person set his foot on the surface of the Moon. Astronaut Neil Armstrong made the first step on the Moon from Apollo 11’s landing craft designated named the Eagle on July 20, 1969. He summed up this monumental event with his well-known prediction: “That is one small step for [a] man; one giant leap for mankind”. The moon landing is seen as the highest point of U.S. space program motivated by a long-running space race with the former Soviet Union. Twelve years before the Apollo 11 mission, the Soviet Union launched the first satellite into the Earth’s orbit. and Antonín Vítek.