A method for estimation of elastic wave velocity anisotropy based on ultrasonic sounding data during rock-sample loading was developed. The subject matter of the method is approximation of ultrasonic sounding data by triaxial velocity ellipsoid. The applicability of proposed method was verified on investigation of anisot ropic rock samples. Laboratory loading of migmatite samples was realized under various mutual orientations between acting force direction and rock foliation - perpendicular, parallel and under 45°. P-ve velocity of ultrasound waves was monitored by 8 sensors network. The velocity ellipsoid was computed and changes of sizes and waorientation its main axes during loading were analyzed for separate experiments with regard to loading level. It was found, that independently to mutual orientation between rock foliation and loading direction, the minimum velocity vector turns to perpendicular direction to final rupture plane and maximum velocity vector turns to the plane of final rupture., Matěj Petružálek, Jan Vilhelm, Tomáš Lokajíček and Vladimír Rudajev., and Obsahuje bibliografické odkazy
Patients suffering from Parkinson's disease must periodically undergo a series of tests, usually performed at medical facilities, to diagnose the current state of the disease. Parkinson's disease progression assessment is an important set of procedures that supports the clinical diagnosis. A common part of the diagnostic train is analysis of speech signal to identify the disease-specific communication issues. This contribution describes two types of computational models that map speech signal measurements to clinical outputs. Speech signal samples were acquired through measurements from patients suffering from Parkinson's disease. In addition to direct mapping, the developed systems must be able of generalization so that correct clinical scale values can be predicted from future, previously unseen speech signals. Computational methods considered in this paper are artificial neural networks, particularly feedforward networks with several variants of backpropagation learning algorithm, and adaptive network-based fuzzy inference system (ANFIS). In order to speed up the learning process, some of the algorithms were parallelized. Resulting diagnostic system could be implemented in an embedded form to support individual assessment of Parkinson's disease progression from patients' homes.
Photosynthetic parameters including net photosynthetic rate (P N), transpiration rate (E), water-use efficiency (WUE), and stomatal conductance (g s) were studied in indoor C3 plants Philodendron domesticum (Pd), Dracaena fragans (Df), Peperomia obtussifolia (Po), Chlorophytum comosum (Cc), and in a CAM plant, Sansevieria trifasciata (St), exposed to various low temperatures (0, 5, 10, 15, 20, and 25°C). All studied plants survived up to 0°C, but only St and Cc endured, while other plants wilted, when the temperature increased back to room temperature (25°C). The P N declined rapidly with the decrease of temperature in all studied plants. St showed the maximum P N of 11.9 μmol m-2 s-1 at 25°C followed by Cc, Po, Pd, and Df. E also followed a trend almost similar to that of P N. St showed minimum E (0.1 mmol m-2 s-1) as compared to other studied C3 plants at 25°C. The E decreased up to ≈4-fold at 5 and 0°C. Furthermore, a considerable decline in WUE was observed under cold stress in all C3 plants, while St showed maximum WUE. Similarly, the g s also declined gradually with the decrease in the temperature in all plants. Among C3 plants, Pd and Po showed the maximum g s of 0.07 mol m-2 s-1 at 25°C followed by Df and Cc. However, St showed the minimum gs that further decreased up to -4-fold at 0°C. In addition, the content of photosynthetic pigments [chlorophyll a, b, (a+b), and carotenoids] was varying in all studied plants at 0°C. Our findings clearly indicated the best photosynthetic potential of St compared to other studied plants. This species might be recommended for improving air quality in high-altitude closed environments., S. M. Gupta, A. Agarwal, B. Dev, K. Kumar, O. Prakash, M. C. Arya, M. Nasim., and Obsahuje seznam literatury
Mitochondrial dysfunction is currently acknowledged as a central
pathomechanism of most common diseases of the 21st century.
Recently, the assessment of the bioenergetic profile of human
peripheral blood cells has emerged as a novel research field with
potential applications in the development of disease biomarkers.
In particular, platelets have been successfully used for
the ex vivo analysis of mitochondrial respiratory function in
several acute and chronic pathologies. An increasing number of
studies support the idea that evaluation of the bioenergetic
function in circulating platelets may represent the peripheral
signature of mitochondrial dysfunction in metabolically active
tissues (brain, heart, liver, skeletal muscle). Accordingly,
impairment of mitochondrial respiration in peripheral platelets
might have potential clinical applicability as a diagnostic and
prognostic tool as well as a biomarker in treatment monitoring.
The aim of this minireview is to summarize current information in
the field of platelet mitochondrial dysfunction in both acute and
chronic diseases.
An expedition was undertaken to French Guiana in search of amphibian parasites. Of the 23 anuran species collected and screened for polystomes, the toad Rhinella margaritifera (Laurenti) was the sole species found to be infected with a polystome, namely Wetapolystoma almae Gray, 1983. Of the two caecilian species collected, a new species of Nanopolystoma du Preez, Huyse et Wilkinson, 2008 was discovered from the urinary bladder of the aquatic caecilian Typhlonectes compressicauda (Duméril et Bibron). The small size of the mature worm, two non-diverticulated caeca of equal length that are non-confluent posteriorly, vitelline follicles in two dense lateral fields, a single follicular testis in the middle of the body, small ovary and a single operculated egg in utero, vaginae present and the caecilian host allowed the identification of the specimen as Nanopolystoma. Larger body size, hamulus length, egg diameter and occurrence in the caecilian family Typhlonectidae distinguishes the new species from the two other known polystomes in Nanopolystoma; thus, the description of Nanopolystoma tinsleyi sp. n. is provided within this paper.
The rockfall hazard in high hills of deccan pleatue has been one of the major disasters in western part of India. The present study aimed to assess the stability of hill cut highway slope near Khandala Tunnel along Mumbai-Pune expressway, Maharashtra, India. This study is significant as the Khandala tunnel is one of the five tunnels situated along the Mumbai-Pune expressway, which experiences frequent rockfall and slope instability, mostly in the rainy season. The assessment of slope failure in the present study performed by a combination of rockfall simulation and 2D slope stability analysis. The results of the slope analysis show that the slope is stable in dry condition having a factor of safety (FoS) 1.48. In contrast, it becomes very critical during the rainy season having FoS of 1.07. Rockfall analysis shows that the boulders came down on both carriageways with approximate maximum bounce height, total kinetic energy, and translational velocity of 9 m, 500 kJ, and 16 m/s, respectively. The preventive slope stabilisation measures suggested to minimise the failure problems and to capture the movement of falling blocks before reaching the road.
Cuttings of five Populus alba clones (S18 F1-26, Al29 F8-35, J3 F1-4, GU1 F16-36, PO9 F21-88), Populus euphratica, and Populus×euramericana (I-214) were submitted during 45 d to regular watering with NaCl solutions of electrical conductivity of 7 and 14 dS m-1. Chlorophyll a fluorescence in response to the salinity stress was assessed, using F0 and Fv/Fm. Differences in reaction to the salt were found in P. alba clones, F0 and Fv/Fm being the fluorescence parameters used to check out this stress. Minimal constant fluorescence of dark-adapted plants (F0) showed a better correlation with the disease index exhibited by plants and also with salinity dose than the parameter Fv/Fm. Some of the P. alba clones showed the same behaviour, assessed through fluorescence parameters, as P. euphratica, which was previously defined as salt tolerant, while the rest exhibited the same characteristics as I-214, which was very sensitive. and H. Sixto, I. Aranda, J. M. Grau.
The increasing worldwide production of bisphenols has been associated to several human diseases, such as chronic respiratory and kidney diseases, diabetes, breast cancer, prostate cancer, behavioral troubles and reproductive disorders in both sexes. The aim of the present in vitro study was to evaluate the potential impact bisphenols A, B, S and F on the cell viability and testosterone release in TM3 Leydig cell line. Mice Leydig cells were cultured in the presence of different concentrations of bisphenols (0.04-50 µg.ml-1 ) during 24 h exposure. Quantification of the cell viability was assessed using the metabolic activity assay, while the level of testosterone in cell culture media was determined by enzyme-linked immunosorbent assay. Within the panel of substances under investigations, the higher experimental concentrations (10; 25 and 50 µg.ml-1 ) significantly (P<0.001) decreased Leydig cells viability, while the same doses of BPA and BPB also reduced testosterone production significantly (P<0.001). Taken together, the results of our study reported herein is a consistent whit the conclusion that higher experimental doses of bisphenols have a cytotoxic effect and could have a dose-dependent impact on testosterone production.
Waterlogging is one of the critical factors controlling the distribution, regeneration, and survival of vegetation in wetlands. Here, we tested the hypothesis that Mitragyna parvifolia (Roxb.) Korth. and Syzygium cumini Keels, inhabiting the Keoladeo National Park, a Ramsar wetland (Bharatpur, India), are tolerant to waterlogging. The morphological and photosynthetic variables of four-month-old seedlings subjected to waterlogging, along with the concentrations of macroand micronutrients, were examined. After 35 days, treatment was halted due to high mortality of S. cumini seedlings in contrast to that of M. parvifolia seedlings. Significant declines in most of the studied variables were observed in both species when compared with their respective controls. In addition, M. parvifolia seedlings developed adventitious roots and lenticels and showed an increased root biomass. Based on the results, we concluded that adaptive traits displayed by M. parvifolia seedlings facilitate its tolerance to waterlogging in contrast to S. cumini seedlings., A. Bidalia, Z. Okram, M. Hanief, K. S. Rao., and Obsahuje bibliografii