Academic detailing, also known as prescriber support and education, is the service of sending trained clinicians to physicians’ offices in order to present the best available, objective scientific evidence in a given therapeutic area. We describe and review experience with academic detailing programs. We conclude that the academic detailing program could be tried in the Czech Republic, Ludwig O. Dittrich, and Literatura
Clinical oncologists have been focusing their efforts on attempting to define risk groups of patients with unusual biological reactions to the recommended therapy regimens using molecular biology techniques. The aims of our study were: (i) to find a design and validate a method for fast and reliable analysis of the D1853N (5557G>A) genetic polymorphism in the ATM (ataxia-telangiectasia mutated) gene; (ii) to use side-directed mutagenesis to generate ATM 5557A-positive DNA (reference ATM5557A DNA); and (iii) to analyze a group of patients suffering from cervical carcinoma with adverse responses to radiotherapy. The 5557A variant was found in three of twenty women (15%). Our data show that the prevalence of the 5557A allelic variant in cervical cancer subjects with adverse responses after irradiation probably does not differ from the prevalence common in Caucasians. A larger population study should confirm these preliminary results., Martin Beránek, Monika Drastíková, Simona Paulíková, Igor Sirák, Milan Vošmik, Jiří Petera, and Literatura 31
Příspěvek nabízí stručný přehled odlišných přístupů ke studiu člověka, jež může být pojímáno jako celostní bio-socio-kul- turní disciplina čerpající jak z přírodních / exaktních, tak humanitních věd, či jako dvě odlišné skupiny „vědeckých“ (čti: přírodovědných) a „nevědeckých“ (společenskovědních) výzkumů, jež se vzájemně metodologicky a terminologicky stále vzdalují, ale ze zvyku jsou stále označovány za antropologii, a to na pozadí nedávné kontroverze vyvolané rozhodnutím Americké antropologické asociace vymýtit pojem „věda“ z dlouhodobého programu organizace. Obsaženo je i krátké ohlédnutí za 1. ročníkem našeho časopisu jako otevřené publikační plat- formy integrálně chápané antropologie., The contribution presents a brief overview of different approaches to the study of Man, conceived as a holistic bio-socio-cultural scientific discipline drawing upon natural / exact sciences and humanities, or increasingly diverging “scientific” and “non-scientific” research- es, both from force of habit still termed anthropology, in the background of recent controversy sparkled by the decision of the American Anthropological Association to purge the term “science” from its long-term mission statement. Included is also a short retrospective glance at the first volume of our journal as an open publication platform of integrally conceived anthropology., Jan Filipský, and Literatura