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2. 11. Světový kongres fetální medicíny, 24.–28. června 2012

Creator:
Belošovičová, Hana and Calda, Pavel
Format:
braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, and TEXT
Subject:
kongresy jako téma, prenatální diagnóza, financování organizované, asistovaná reprodukce, ženské pohlaví, vrozené vady--chirurgie, plod, novorozenec, mikročipová analýza, první trimestr těhotenství, těhotenské testy, and těhotenství
Language:
Czech
Description:
Hana Belošovičová, Pavel Calda
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

3. 18-F cholin PET CT v primodiagnostice karcinomu prostaty

Creator:
Kudláčková, Šárka, Král, Milan, Koranda, Pavel, and Študent, Vladimír
Format:
electronic, electronic resource, and remote
Type:
model:article, article, Text, and TEXT
Language:
Czech and English
Description:
Cíl: Zjistit přínos 18F-fluorocholinového PET/ CT (18F-FCH PET/CT) pro cílenou biopsii prostaty u pacientů s opakovaně negativními biopsiemi a trvajícím podezřením na přítomnost karcinomu prostaty. Soubor pacientů a metoda: Od ledna 2013 do května 2015 jsme provedli 18-F-FCH PET/CT cholinové PET CT vyšetření u 30 pacientů. Indikačním kritériem bylo PSA nad 10 ng/ml a prodělání více než tři biopsií prostaty, včetně biopsie saturační. Pokud to bylo možné, pak pacienti předem prodělali šestitýdenní kůru ATB terapie Doxycyklinem 100mg 2x denně k eliminaci zánětu, a tím možným falešně pozitivním nálezům na 18F-FCH PET/CT. Poté bylo provedeno PET/CT vyšetření a následně s odstupem byla provedena cílená biopsie ložisek popsaných na 18F-FCH PET/CT. Cílená biopsie byla provedena pod sonografickou kontrolou transrektálně za pomoci kognitivní fúze PET/CT obrazu s real-time sonografickým záznamem. Byly odebírány jen vzorky z ložisek popsaných na PET/CT. Výsledky: Od ledna 2013 do května 2015 absolvovalo 18F-FCH PET/CT 30 pacientů. Průměrný věk pacientů byl 66 let v rozmezí 57–75 let. U 14 z nich jsme potvrdili karcinom prostaty, což činí 46% záchyt ve skupině rebiopsií. Všichni tito pacienti měli Gleasonovo skóre vyšší než sedm a PSA vyšší než 20 ng/ml. Závěr: V našem souboru jsme prokázali přínos 18F-FCH PET/CT u pacientů s opakovaně negativními biopsiemi a pokračující elevací PSA, u kterých nebyl karcinom prostaty standardním způsobem detekován. Ložisko vyznačené pomocí 18F-cholinufluorocholinu umožnilo cílenou biopsii pod sonografickou kontrolou. V současnosti není jednoznačné doporučení, jak postupovat u pacientů, u kterých máme opakovaně negativní biopsie prostaty a trvá podezření na přítomnost karcinomu. Využití 18F-FCH PET/CT se jeví jako jedna z mož- ností., Aim: The aim of the study was to determine the benefits of 18F-fluorocholine PET/CT in patients with repeated negative biopsies and continued suspicion of prostate carcinoma. Material and methods: 18F-fluorocholine PET/CT (18F-FCH PET/CT) was performed with 30 patients from January 2013 until May 2015. Indication criteria were PSA above 10 ng/ml and three biopsies. If possible patients underwent six weeks treatment of antibiotic therapy with Doxycyclin 100mg twice per day to eliminate inflammation and possible false findings in PET/CT. Then PET/CT was performed with following targeted biopsy of focus from 18F-FCH PET/CT. Targeted biopsy was done under the sonographic transrectal control with the help of cognitive fusion PET/CT image with real-time sonography. Only samples from centers identified with PET/CT were taken. Results: From January 2013 until May 2015 30 patients underwent 18F-FCH PET/CT. Average age of patients was 66 years (57–75 years). We confirmed prostate cancer in 14 of them which is 46 % success in rebiopsy group. All these patients had Gleason score above seven and PSA higher than 20 ng/ml. Conclusions: We have shown in our sample the benefits of 18F-cholinFCH PET/CT in patients with repeated negative biopsies and continued PSA elevation, where prostate carcinoma was not detected in standard biopsies. The use of 18F-FCH PET/CT seems promising in diagnostic of prostate cancer where 18F-fluorocholine can be found also in slow growing cells of majority of prostate carcinoma. Using this method we can diagnose also tumors, which are located outside of typical areas in the peripheral zone and therefore can be missed even in repeated biopsies., Šárka Kudláčková, Milan Král, Pavel Koranda, Vladimír Študent, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

5. 2nd CCP Phenogenomics Conference 2020: abstract book: Vestec, 17-18 September 2020

Creator:
Ústav molekulární genetiky (Akademie věd ČR), České centrum pro fenogenomiku, and CCP Phenogenomics Conference (2020 : Vestec, Praha-západ, Česko)
Publisher:
Institute of Molecular Genetics of the Czech Academy of Sciences
Format:
electronic, electronic resource, remote, bez média, online zdroj, and 89 stran : ilustrace, převážně barevné, portréty
Type:
model:monograph and TEXT
Subject:
Obecná genetika. Obecná cytogenetika. Evoluce, fenogenomika, molekulární genetika, phenogenomics, molecular genetics, 575.111:575.21, 577.21, (062.534), (048.3), 2, and 575
Language:
English
Description:
Název z obálky and born digital
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

7. 3rd CCP Phenogenomics Conference 2021: abstract book: virtual conference: Vestec, 16-17 September 2021

Creator:
Ústav molekulární genetiky (Akademie věd ČR), České centrum pro fenogenomiku, and CCP Phenogenomics Conference (2021 : Vestec, Praha-západ, Česko)
Publisher:
Institute of Molecular Genetics of the Czech Academy of Sciences
Format:
electronic, electronic resource, remote, bez média, online zdroj, and 69 stran : ilustrace, převážně barevné, portréty
Type:
model:monograph and TEXT
Subject:
Obecná genetika. Obecná cytogenetika. Evoluce, fenogenomika, molekulární genetika, phenogenomics, molecular genetics, 575.111:575.21, 577.21, (062.534), (048.3), 2, and 575
Language:
English
Description:
Název z obálky and born digital
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

8. 4th CCP Phenogenomics Conference 2022: abstract book: hybrid conference: Vestec, 15-16 September 2022

Creator:
Ústav molekulární genetiky (Akademie věd ČR), České centrum pro fenogenomiku, and CCP Phenogenomics Conference (2022 : Vestec, Praha-západ, Česko)
Publisher:
Institute of Molecular Genetics of the Czech Academy of Sciences
Format:
electronic, electronic resource, remote, bez média, online zdroj, and 82 stran : ilustrace, převážně barevné, portréty
Type:
model:monograph and TEXT
Subject:
Obecná genetika. Obecná cytogenetika. Evoluce, fenogenomika, molekulární genetika, phenogenomics, molecular genetics, 575.111:575.21, 577.21, (062.534), (048.3), 2, and 575
Language:
English
Description:
Název z obálky and born digital
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

10. 8th International Symposium on Kallikreins and Kallikrein-Related Peptidases: Prague, 25-27 September 2019 : final programme & abstract book

Creator:
Ústav molekulární genetiky (Akademie věd ČR) and International Symposium on Kallikreins and Kallikrein-Related Peptidases 2019 : Praha, Česko)
Publisher:
Institute of Molecular Genetics CAS
Format:
electronic, electronic resource, remote, bez média, online zdroj, and 78 stran
Type:
model:monograph and TEXT
Subject:
Biochemie. Molekulární biologie. Biofyzika, molekulární genetika, enzymy, molecular genetics, enzymes, kallikrein, 577.21, 577.15, 612.015.1, 615.355, (048.3), (062.534), 2, and 577
Language:
English
Description:
Název z obálky, Obsahuje bibliografii a bibliografické odkazy, and born digital
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

11. A comparison of aggression and impulsivity between smokers and non-smokers

Creator:
Zaidi, Uzma
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, srovnávací studie, and TEXT
Subject:
kouření--epidemiologie--psychologie--škodlivé účinky, agrese--psychologie, impulzivní chování, poruchy vyvolané užíváním tabáku--psychologie, průzkumy a dotazníky, studenti, dospělí, lidé, and mužské pohlaví
Language:
English
Description:
The study aimed to investigate the role of aggression and impulsivity in smoking among male adult students. It was hypothesized that there would be significant difference between smokers and non- smokers on the traits of aggression and impulsivity. The sample of two hundred male adult students was selected from different universities of Islamabad. Two subscales of Impulsiveness and Aggression were administered to measure the personality traits of aggression and impulsivity. Descriptive statistics and t-test was calculated for analysis of data. Results showed that there is significant differences in aggression and impulsivity between smokers and non-smokers. The result can be helpful for psychologist and other professionals to plan public health therapeutic and social reengineering interventions for youth., Uzma Zaidi, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

12. A cutaneous horn mimicking polydactyly: a case report

Creator:
Tamer, Funda and Yuksel, Mehmet Eren
Format:
electronic, electronic resource, and remote
Type:
model:article, article, Text, and TEXT
Language:
English
Description:
A cutaneous horn is a general name for cornified material protruding from skin. On the other hand, polydactyly is a common congenital anomaly of the hand and foot which is characterized by extra finger or toe. A cutaneous horn might mimick polydactyly by resembling an extra toe. Hereby, we present a 72-year-old white Caucasian male with an extra toe-like projection on his fourth toe. Initially, polydactyly was suspected, however a cutaneous horn was also considered. The lesion was surgically removed. The histopathological examination of the specimen revealed hyperkeratosis, and thus confirmed the lesion to be a cutaneous horn., Funda Tamer, Mehmet Eren Yuksel, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

13. A giant perineal nevus lipomatosus superficialis: case report

Creator:
Tamer, Funda and Yuksel, Mehmet Eren
Format:
electronic, electronic resource, and remote
Type:
model:article, article, Text, and TEXT
Language:
English
Description:
Nevus lipomatosus superficialis is a rare hamartomatous malformation which is composed of ectopic adipocytes in the dermis. It was first reported in 1921 by Hoffmann and Zurhelle. Two clinical forms of nevus lipomatosus superficialis have been described: classical (multiple) and solitary. Classical form of nevus lipomatosus superficialis is usually found on pelvic girdle, trunk, buttocks and thighs as soft, skin colored papules or nodules. It is usually present at birth or it appears in the first two decades of life. The solitary form of lipomatosus superficialis appears as a solitary papule or nodule on the back, scalp and arms of the patients with late onset. The lesions are usually asymptomatic, however some patients may complain about pain and itching. Malignant transformation of nevus lipomatosis superficialis has not been reported yet. Therefore, surgical intervention is only necessary for the patients who have cosmetic concerns. Recurrence after surgical removal is very rare. Perineum is an uncommon localization for nevus lipomatosus superficialis. Hereby, we report a 55-year-old Caucasian female with a 6x5,5x4 cm mass in the perineal region. The patient had cosmetic concerns, therefore she wanted the lesion to be removed surgically. The lesion was surgically removed. The histopathological evaluation of the specimen revealed nevus lipomatosus superficialis. A solitary type of giant nevus lipomatosus superficialis in the perineal region of a patient over the age of 50 is a very rare condition. Even rarely seen, nevus lipomatosus superficialis should be kept in mind in the differential diagnosis of perineal masses., Funda Tamer, Mehmet Eren Yuksel, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

14. A non healing ulcer on scalp

Creator:
Deshpande, Deepal J., Nayak, Chitra S., and Mishra, Sunil N.
Format:
braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, kazuistiky, and TEXT
Subject:
staří, nádory hlavy a krku--diagnóza--patologie, hemangiosarkom--diagnóza--patologie, lidé, mužské pohlaví, skalp, nádory kůže--diagnóza--patologie, and kožní vředy--diagnóza
Language:
English
Description:
Angiosarcoma is a soft tissue tumour with a dismal prognosis. We present a 74 year old male presenting with a non healing ulcer on the scalp. On histopathology a diagnosis of angiosarcoma was made. An early diagnosis and tumour size play a pivotal role in the survival of the patient., Deepal J Deshpande, Chitra S Nayak, Sunil N Mishra, and Literatura 6
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

17. Academic Detailing programy a medicína faktu

Creator:
Dittrich, Ludwig O.
Format:
11-14, braille, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, statistics, and TEXT
Subject:
lidé, medicína založená na důkazech, léky na předpis--ekonomika, and péče o pacienta
Language:
Czech and English
Description:
Academic detailing, also known as prescriber support and education, is the service of sending trained clinicians to physicians’ offices in order to present the best available, objective scientific evidence in a given therapeutic area. We describe and review experience with academic detailing programs. We conclude that the academic detailing program could be tried in the Czech Republic, Ludwig O. Dittrich, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

18. Access to financial resources and environmental migration of the poor

Creator:
Rakhmetova, Aizhamal, Hoffmann, Roman, Pytliková, Mariola, Jeong, Byeongju, Univerzita Karlova. Centrum pro ekonomický výzkum a doktorské studium, and Národohospodářský ústav (Akademie věd ČR)
Publisher:
CERGE-EI
Format:
electronic, electronic resource, remote, bez média, online zdroj, and 1 online zdroj (36 stran : tabulky, grafy, mapy).
Type:
model:monograph and TEXT
Subject:
Znečištění a poškození životního prostředí, klimatické změny, environmentální migrace, adaptace na změnu klimatu, finance, climate changes, environmental migration, climate change adaptation, Indonésie, Indonesia, 504.7:551.583, 314.15:502/504, 502.13:551.583, 336, (594), (0.034.2:08), (048.8), 2, and 504
Language:
English and Czech
Description:
Aizhamal Rakhmetova, Roman Hoffmann, Mariola Pytliková., Obsahuje bibliografii a bibliografické odkazy, České a anglické resumé, and born digital
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

20. Adaptability of students with different individual and typological peculiarities of vegetative functions regulation

Creator:
Tananakina, Tatiana, Lila, Natalya, Ivasenko, Anzhelika, Bolgov, Dmitrij, Mavrich, Svetlana, and Modna, Yuliya
Format:
electronic, electronic resource, remote, and elektronický zdroj
Type:
model:article, article, Text, hodnotící studie, and TEXT
Subject:
adaptace fyziologická, autonomní nervový systém--fyziologie, fyziologické jevy, srdeční frekvence--fyziologie, časná diagnóza, hodnocení rizik, mladiství, dospělí, ženské pohlaví, lidé, mužské pohlaví, studenti, and výchova, vzdělávání
Language:
English
Description:
In the last decade the health of young people in Ukraine as well as in many other countries of the world significantly deteriorated according to the results of screening tests. Because of this the main task of prophylactic medicine is development and introduction of new methods of early diagnostics of diseases. The aim of the work to assess the peculiarities of adaptation of students with different types of vegetative regulation. Material and methods: 415 second year students of Lugansk State Medical University were tested. The mechanisms of physiological functions of the body regulation were assessed by registration of cardiac rhythm variability (CRV). Analysis of CRV was performed by three methods: statistical, geometrical, and spectral analysis. The express method proposed by Shlyk, N.I. (2009) was later used to determine the prevailing type of vegetative regulation. To assess adaptability the method of R.M. Baevskij (1979) was used. Results: In the result of investigation 4 types of functional states of regulatory systems were determined: I type 295 (71 %) of tested, II in 14 (3 %), III in 96 (23 %) and IV only in 10 (2%). I type of functional state of regulatory systems in the wakeful state at rest was characterized by moderate prevalence of central regulation of heart rhythm (MPCR), decreased activity of autonomic regulation. It was noticed that some of the parameters of CRV (like R­R, SDNN, RMSSD and pNN50) which characterize autonomic regulation, were statistically lowere (р≤0.01) compared to type III, and some (like AMo and SI) higher, in both female and male students. Summarized spectrum capacity and components of its wave structure (HF, LF, VLF) which characterize central regulation were statistically significantly lower (р≤0.01) for the I type of regulation compared to the III one which is characterized by moderate prevalence of autonomic regulation of the heart rhythm. In female students with type I autonomic regulation compared to male students such CRV parameters as R­R and AМo were statistically significantly lower (р≤0.05), while the parameters of total potency (TP) and high frequency waves (HF) were higher (р≤0.05), which could point to more centralized heart rhythm regulation in male compared to female. The evaluation of regulatory systems overstress allowed to determine the state of adaptation and risk of overstress or breakdown in students with different types of autonomic regulation. Conclusions: Thus, evaluation of adaptation state in students with different types of autonomic regulation allows to characterize the current functional state and uncover the risk of disease development., Tatiana Tananakina, Natalya Lila, Anzhelika Ivasenko, Dmitrij Bolgov, Svetlana Mavrich, Yuliya Modna, and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

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