The study deals with the fates of monastery of Nepomuk (Pomuk) in exile in the time of Hussite wars. The core is compresed of an analysis of newly found sources, particularly the accounts of the court of the Ebrach Abbey in Nuremburg. Here, the exiles had part of their financial reserves deposited, acquired from the sale and pledge of valuables and books of their cloister. On blank folios of the accounts, there are drafts of letters by the administrator of the court, Hermann of Kottenheim, for the Nepomuk exiles. The mentioned sources deliver a detailed testimony on the as yet unknown place of their residence, the composition, functioning, and financing of the Nepomuk exile monastery. It was also possible to correct the idea that the Nepomuk monks set out for their maternal abbey of Ebrach immediately after the Hussite wars broke out. The core of the monastery resided at the economic court in Weinzierl bei Krems and was finally disbanded only after 1430 when the exiles ran out of finances., Ondřej Vodička., and Obsahuje literaturu a odkazy pod čarou
Selective serotonine reuptake inhibitors (SSRI) are believed to be less dangerous in the treatment of depressive disorder in comparison with tricyclic antidepressants (TCA) due to their relative lack of cardiotoxicity. Thus, we investigated the effect of citalopram (SSRI) on membrane electrophysiology in rat cardiomyocytes in tissue culture. The results were compared with those from amitriptyline (TCA). The whole-cell configuration patch-clamp technique was used. Both citalopram and amitriptyline exhibited the concentration-dependent inhibition of the L-type calcium channel current (ICa). Citalopram in concentrations of 3 mM and 10 mM inhibited peak calcium current by 2.7 % and 8 %, respectively. We demonstrated the same potency of citalopram and amitriptyline to inhibit ICa. These observations led us to conclude that citalopram and amitriptyline are drugs, which exhibit a similar potency for causing concentration-dependent inhibition of ICa., J. Hamplová-Peichlová, J. Krůšek, I. Paclt, J. Slavíček, V. Lisá, F. Vyskočil., and Obsahuje bibliografii
This article explores some of the debates surrounding the gendered impact of both the démocratisation process and European Union enlargement on the countries of Central and Eastern Europe. It focuses on three key issues of gender-equitable citizenship: debates about the best mechanisms for achieving gender equality in mainstream politics; questions about the efficacy of civil society activism in relation to mainstream politics; and the pros and cons of gender mainstreaming as a key component of EU enlargement. It also raises the question of the most appropriate frame for achieving more gender-equitable societies: the nation-state or supra-national institutions such as the European Union.
During the reign of the empress Maria Theresa and in particular of her successor Joseph II, the Habsburg monarchy went through substantial changes. The state took control of parts of public life which had until then been independent. Besides arts, which started to be controlled through the state academy, architecture became the centre of attention. Architecture regulated by state was supposed to observe the so called architectura civilis (Bürgerliche Baukunst) the principles of which had been formulated by German and Austrian theoreticians and mathematicians in the second half of the 18 century. The main features typical for the architectura civilis were simplicity, practicality and economy, which suited the enlightened state. Architects and engineers with profound theoretical knowledge who were able to respond to a wide spectrum of assignments became important for the intentions of the state. Designers who did not make part of the guild structure and who had such wide competences that they could design architecture normally designed by engineers - fortifications, roads, and bridges were considered as ideal. This study focuses on the professional bibliography of two significant engineers working in the service of the estates and the state in Moravia at the last years of 18 century Johann Anton Krzoupal von Grünnenberg, and first Director of the Provincial Building Directorates in Brno Karl Jacobi von Eckholm., Michal Konečný., and Obsahuje bibliografické odkazy