Our previous preliminary results pointed to possible seasonal variations in Mg2+-ATPase activity of rat heart mitochondria (MIT). It is not too surprising since seasonal differences were already reported in myocardial function, metabolism and ultrastructure of the intact as well as hemodynamically overloaded rabbit hearts and also in other tissues. The present study is aimed to elucidate whether seasonal differences observed in rat heart MIT Mg2+-ATPase activity will be accompanied with changes in membrane fluidity and in the content of conjugated dienes (CD) in the lipid bilayers of MIT membranes as well as whether the above seasonal differences will also be present in the diabetic heart. Our results revealed that values of Mg2+-ATPase activity in the winter/spring-period (W/S-P) exceeded significantly (p<0.05-0.001) those in the summer/autumn-period (S/A-P). Similar trend was also observed in hearts of animals with acute (8 days) streptozotocin diabetes. With the exception of values of CD in the S/A-P, all values of Mg2+-ATPase activities, membrane fluidity and CD concentrations in diabetic hearts exceeded those observed in the healthy hearts. Our results indicate that seasonal differences may play a decisive role in the evaluation of properties and function of rat heart MIT., J. Mujkošová, M. Ferko, P. Humeník, I. Waczulíková, A. Ziegelhöffer., and Obsahuje bibliografii a bibliografické odkazy
The laboratory rat, a non-photoperiodic rodent, exhibits seasonal fluctuations of melatonin. Melatonin has been found to be readily transferred from the maternal to the fetal circulation. No data exist on the possible influence of maternal pineal gland upon seasonal variations of the offspring. The aim of the present study was to asses the influence of the maternal melatonin rhythm on the offspring postnatal development of the reproductive hormones LH, FSH and prolactin. Male offspring from control, pinealectomized (PIN-X) and PIN-X + melatonin (PIN-X+MEL) mother Wistar rats were studied at 21, 31, and 60 days of age. Seasonal age-dependent variations were found for all hormones studied in control offspring but PIN-X offspring showed a tendency to have reduced duration or altered seasonal variations. Maternal melatonin treatment to PIN-X mothers partially restored the effect of pinealectomy. The chronological study of LH, FSH, and prolactin in PIN-X offspring also showed an altered pattern as compared to control-offspring. Melatonin treatment to the mothers partially restored the developmental pattern of reproductive hormones. Results of this study indicate that maternal pineal gland of the laboratory rat is involved in the seasonal postnatal development variations of reproductive hormones of the offspring., N. Vásquez, E. Díaz, C. Fernández, V. Jiménez, A. Esquifino, B. Díaz., and Obsahuje bibliografii a bibliografické odkazy
Compact conical strain gauge probe for borehole over-coring rock massif stress measurement (CCBO), based on experiences of K. Sugavara and Y. Obara, has been developed in Institute of Geonics ASCR, v.v.i. from 2004. First generation of CCBO is equipped by simple electronic circuit which requires continuous communication with control computer in the course of measurement. Prototypes of this type probes are used for long term stress changes monitoring induced by longwall advancement in mine. Solving of continuous data communication through rotating drilling tool filled by wash water in course of over-coring is very difficult technical task, which is not possible to solve in terms of grant project. To avoid this problem a development of second generation of CCBO equipped by microprocessor and internal data logger was initialised. Simplified modification of CCBO is developed as a probe for long-term monitoring of rock massif stress changes (Compact Conical Ended Borehole Monitoring - CCBM). Design of both models probes, discussion of measurement errors and technique of sensitivity self-calibration is described., Jaromír Knejzlík, Zdeněk Rambouský, Kamil Souček and Lubomír Staš., and Obsahuje bibliografii
Zaměříme se na šedesátiletou existenci Spojeného ústavu jaderných výzkumů (SÚJV) v Dubně z poněkud jiného pohledu - nikoliv z pohledu jaderného fyzika, ale jaderného fyzika filatelisty. Během šedesátileté existence ústavu bylo v různých členských zemích vydáno osm poštovních známek, bylo použito několik příležitostných razítek a byly vydány přítisky na obálkách i dopisnicích, které mají vztah k SÚJV. and Zdeněk Janout.