Brain Awareness Week is a series of events held around the world to increase public awareness of the brain. Top Czech scientists attracted more then 1,300 students with lectures as part of the annual Brain Awareness Week that took place in the administration building of the Czech Academy of Sciences extending from 10-13 March 2008. and Gabriela Adámková.
Tento text představuje komplexní úvod k systému NESSTAR. Je určen především (potenciálním) uživatelům tohoto programového balíku, určeného pro publikování, prohledávání a analýzu dat na webu. V úvodní části je popsán vznik tohoto programu, jeho jednotlivé části a také možnosti, které nabízí producentům a depozitorům dat. V druhé části je pak Nesstar představen jako nástroj pro on-line prohledávání a analýzu dat. Jde současně o uživatelský manuál, který by měl ukázat cestu k sociologickým datům na internetu., Tomáš Čížek, Martin Vávra., 22 obrázků, and Obsahuje bibliografii
Online psychoterapie je dnes respektována jako svébytné uspořádání psychosociální léčby. V současnosti se pozornost výzkumníků zaměřuje především na její efektivitu. Autoři nabízejí přehled 30 studií zabývajících se účinností online psychoterapie. Shromáždili ty výzkumy, v nichž se ověřovala účinnost jedné ze tří základních forem online léčby: svépomocný online psychoterapeutický program bez kontaktu s terapeutem, svépomocný online psychoterapeutický program s minimálním kontaktem s terapeutem a online psychoterapie s terapeutem. Většina studií zkoumala efektivitu KBT intervencí, které trvaly v rozmezí 6–8 týdnů. Účinnost se dnes ověřuje nejčastěji porovnáním s kontrolními skupinami, tvořenými budoucími pacienty na čekací listině. Dvě třetiny studií zahrnuly do výzkumného designu i následné sledování respondentů, nejčastěji po dobu 3–6 měsíců. Ve všech sledovaných studiích se online psychoterapeutické intervence ukázaly jako efektivní prostředek léčby dané psychické poruchy. Ve výzkumech, které zahrnuly kontrolní skupinu, se vždy ukázalo, že absolvování online programu přineslo respondentům více úlevy než zařazení do kontrolní skupiny. Studie, které porovnávaly online intervence s léčbou tváří v tvář, došly ve všech případech k závěru, že obě dvě formy terapie jsou stejně efektivní., Online psychotherapy is now a respected mode of psychosocial treatment. Nowadays the attention of researchers is primarily focused on its effectiveness. Authors provide an overview of 30 studies dealing with the effectiveness of online psychotherapy. They collected surveys focused on the effectiveness of one of three basic forms of online therapy: self-help online psychotherapy program without contact with a therapist, self-help online psychotherapeutic program with minimal contact with the therapist and online psychotherapy with a therapist. Most studies examined the effectiveness of CBT intervention which lasted between 6-8 weeks. Efficiency was mostly measured by the comparison with control groups, made up of patients on the waiting list. Two thirds of the studies included in the research design follow up of the respondents, mostly for 3-6 months. In all the studies online psychotherapeutic interventions proved to be effective means of mental disorders treatment. Studies which included a control group have always shown that completion of the online treatment brought more relief than inclusion in the control group. Studies comparing the online intervention to face to face treatment came in all cases to the conclusion that the two forms of therapy are equally effective., Zbyněk Vybíral, Petra Vondráčková., and Obsahuje seznam literatury
The cis(c)-9, trans(t)-11 (c9,t11) and t10,c12 isomers of conjugated linoleic acid (CLA) have been reported as agonists of peroxisome proliferator-activated receptor (PPAR) and beneficial in lipidemia and glycemia. However, it is unclear whether CLA isomers enhance or antagonize effects of conventional drugs targeting PPAR. Male Sprague-Dawley rats were fed high fat diet (HFD) for 8 weeks and treated without or with CLA, rosiglitazone or both for 4 weeks. Oral glucose tolerance and surrogate markers of insulin resistance were not significantly different for all treatments compared to untreated normal diet (ND) or HFD group, except lipoprotein levels. The combination of CLA and rosiglitazone had suppressed levels of low and high density lipoproteins (46 % and 25 %, respectively), compared to HFD-alone. Conversely, the atherogenic co-efficient of the animals received HFD or HFD+rosiglitazone+CLA was 2-folds higher than ND, HFD+rosiglitazone or HFD+CLA. Isolated aortic rings from the combined CLA and rosiglitazone treated animals were less sensitive to isoprenaline-induced relaxation among endothelium-denuded aortas with a decreased efficacy and potency (Rmax=53±4.7 %; pEC50=6±0.2) compared to endothelium-intact aortas (Rmax=100±9.9 %; pEC50=7±0.2). Our findings illustrate that the combination of CLA and rosiglitazone precede the atherogenic state with impaired endotheliumindependent vasodilatation before the onset of HFD-induced insulin resistance., B. K. Chai, Y. S. Lau, B. J. Loong, M. M. Rais, K. N. Ting, D. M. Dharmani, S. K. Mohankumar., and Obsahuje bibliografii
For a finitely generated group, we study the relations between its rank, the maximal rank of its free quotient, called co-rank (inner rank, cut number), and the maximal rank of its free abelian quotient, called the Betti number. We show that any combination of the group’s rank, co-rank, and Betti number within obvious constraints is realized for some finitely presented group (for Betti number equal to rank, the group can be chosen torsion-free). In addition, we show that the Betti number is additive with respect to the free product and the direct product of groups. Our results are important for the theory of foliations and for manifold topology, where the corresponding notions are related with the cut-number (or genus) and the isotropy index of the manifold, as well as with the operations of connected sum and direct product of manifolds., Irina Gelbukh., and Obsahuje seznam literatury
The nullity of a graph G is the multiplicity of zero as an eigenvalue in the spectrum of its adjacency matrix. From the interlacing theorem, derived from Cauchy’s inequalities for matrices, a vertex of a graph can be a core vertex if, on deleting the vertex, the nullity decreases, or a Fiedler vertex, otherwise. We adopt a graph theoretical approach to determine conditions required for the identification of a pair of prescribed types of root vertices of two graphs to form a cut-vertex of unique type in the coalescence. Moreover, the nullity of subgraphs obtained by perturbations of the coalescence G is determined relative to the nullity of G. This has direct applications in spectral graph theory as well as in the construction of certain ipso-connected nano-molecular insulators., Didar A. Ali, John Baptist Gauci, Irene Sciriha, Khidir R. Sharaf., and Obsahuje seznam literatury