The aim of our study was to evaluate the potential differences in blood pressure (BP) profile in subjects with different forms of primary aldosteronism (PA). Simultaneously, we studied the effects of PA treatment on BP curve. We therefore monitored 24-hour ambulatory blood pressure values in 22 subjects with aldosterone-producing adenoma (APA), 22 subjects with idiopathic hyperaldosteronism (IHA) and 33 subjects with essential hypertension (EH) as controls. We found a significantly attenuated nighttime systolic BP decline in the APA group (P=0.02). Patients with IHA had lower nighttime systolic BP values (P=0.01) and also a diastolic BP decline (P=0.02) during the night in comparison with EH. We did not detect any significant differences in BP profile characteristics between APA and IHA. Specific treatment of primary aldosteronism (adrenalectomy, treatment with spironolactone) led to the normalization of the BP curve with a marked BP decline. Our study thus demonstrates a blunted diurnal BP variability in patients with primary aldosteronism the specific treatment of which normalized previously attenuated nocturnal BP fall., T. Zelinka, J. Widimský., and Obsahuje bibliografii
Stať má dvě části: po typologickém úvodu autor v prvé části zkoumá úlohu životnosti při formovaní aktivní větné perspektivy v PrelE. V druhé části se zabýva frekvencí pádových forem. Autor si je vědom rozdílu mezi první systémově-strukturní a druhou kvantitativní částí stati. Konstatuje, že v dosavadním jazykovědném bádání bývají oba přístupy nedostatečně propojeny, což má mimo jiné příčinu v dosud značně oddělovaném myšlení o langue a o parole. Následkem toho pak systémové analýzy nejsou vždy doplňovány zcela paralelními výzkumy kvantitativními. Stať podle autora ukazuje, že kvantitativní analýzy mají zásadní význam pro porovnávání jazyků. Frekvence je jeden ze základních faktorů, které prostupují i typologii gramatických kategorií. Zanedbávání soustavného kvantitativního výzkumu neprospívá ani vývojovým, ani komparatistickým výzkumným programům.
A double ínductíon mechanism of Dl protein degradatíon in isolated photosystem 2 (PS2) core complexes and reaction centres is described, showing the existence of two potentíal sites for primáty cleavage. Donor side inhibition conditi- o n s (presence of electron acceptors but no electron donors and pH 8.0) trigger the hydrolysis of the Dl protein between the putatíve helices 1 and II on the lumenal side of the thylakoid membrane. This results in the generation of a C-terminal 24 kDa fragment. However, when the donor-side is actíve (presence of electron donors but no electron acceptors and pH 6.0, acceptor side inhibition conditions) both preparations are able to produce a N-terminal 23 kDa fragment, indicating cleavage between helices IV and V, on the stromal side of the membrane.
Two distinct hemocyte populations are determined in the hemolymph of the triatomine bug Triatoma infestans Klug, oenocytoids and plasmatocytes, and their independent origin from separate stem cells is shown. Both hemocyte populations differ considerably in their morphology, ultrastructure and lectin-binding properties. While oenocytoids are quite uniform with easily definable cells which do not to bind any assayed lectin, the plasmatocytes are a very polymorphic population possessing several morphological types and displaying a positive reactivity with lectins.
Let SP be the set of upper strongly porous at 0 subsets of \mathbb{R}^{+} and let Î(SP) be the intersection of maximal ideals I\subseteq SP. Some characteristic properties of sets E \in Î(SP) are obtained. We also find a characteristic property of the intersection of all maximal ideals contained in a given set which is closed under subsets. It is shown that the ideal generated by the so-called completely strongly porous at 0 subsets of \mathbb{R}^{+} is a proper subideal of Î(SP). Earlier, completely strongly porous sets and some of their properties were studied in the paper V.Bilet, O.Dovgoshey (2013/2014)., Viktoriia Bilet, Oleksiy Dovgoshey, Jürgen Prestin., and Obsahuje seznam literatury
High (HI, 200 W m'^) and low (LI, 30 W m"^) irradiance treatments on the cells of cyanobactenum Synechococcus elongatus Nfig., var. thermalis Geitl. strain KOVROV 1972/8 were perfonned in the presence of chloramphenicol (CAP), and with addition of DCMU and hydroxylamine (HA), respectively, at growth (56 °C) and low (20 °C) temperatures, to distínguish allegedly different mechanisms of PS 2 photoinactivation (PS 2 PI). At both temperatures HI caused a decline of Fy and Hill reaction activity (HRA) followed by degradation of Dl and to a lesser extent also D2 protein. Fq increased slowly during irradiance at 56 while at 20 ®C it quickly rose to constant level. Degradation of proteins was slowed at a lower temperature. The presence of DCMU during photoinhibition significantly blocked the Fq rise and also prevented PS 2 protein degradation at both temperatures. The course of PS 2 PI under LI resembled tlmt, observed at HI, but changes were much slower. During irradiation of the cells, in which oxygen evolving complex (OEC) was impaired by HA, we observed: (/) at least a ten-fold faster decline of PS 2 electron transport activity than in the cells vňth fimctional OEC under the same conditions; (2) an extensive degradation not only of Dl and D2, but also of the apoprotein of chlorophyll-protein CP43 {ACP43y, (3) almost complete inhibition of PS 2 protein degradation in the presence of DCMU. Thus under all conditions tested in vivo which do not affect the fimction of OEC, the fimction of OEC, PS 2 PI proceeds via the acceptor side and a fimctional impairment of OEC is necessary for induction of the donor side mechanism. When OEC is impaired (e.g. by HA) this mechanism can come in action.
Two new species of Copris Geoffroy, 1762 are described and illustrated: Copris (subgenus incertae sedis) caobangensis sp. n. from Caobang Province (northern Vietnam) and Copris (Copris) sonensis sp. n. from Thanhhoa Province (central Vietnam). Copris (Copris) szechouanicus Balthasar, 1958 is recorded in Vietnam for the first time and data on the morphology, distribution and ecology of this species are given. An updated species list and an identification key for the Copris species so far known from Vietnam are presented along with detailed photographs of the poorly known species., Van Bac Bui, Kenneth Dumack, Michael Bonkowski., and Obsahuje bibliografii
To date, only a few species of Hepatozoon Miller, 1908 have been described from amphibians and reptiles of South Africa, including two species from anuran hosts, three from saurians, one from chelonians, and two from ophidians. Hepatozoon bitis (Fantham, 1925) and Hepatozoon refringens (Sambon et Seligmann, 1907), parasitising Bitis arientans (Merrem) and Pseudoaspis cana (Linnaeus), respectively, were described in the early 1900s and since then there have been no further species of Hepatozoon described from snakes in South Africa. Blood smears, used in peripheral blood haemogregarine stage morphometrics, and whole blood used in molecular characterisation of haemogregarines were collected from the caudal vein of six snakes of three species, namely Philothamnus hoplogaster (Günther), Philothamnus semivariegatus (Smith) and Philothamnus natalensis natalensis (Smith). For comparison, a comprehensive table summarising available information on species of Hepatozoon from African snakes is presented. Haemogregarines found infecting the snakes from the present study were morphologically and molecularly different from any previously described from Africa and are thus here described as Hepatozoon angeladaviesae sp. n. and Hepatozoon cecilhoarei sp. n. Both haemogregarine species were observed to cause considerable dehaemoglobinisation of the host cell, in case of infection with H. angeladaviesae resulting in a characteristic peripheral undulation of the host cell membrane and karyorrhexis. To the authors' knowledge, these are the first haemogregarines parasitising snakes of the genus Philothamnus Smith described using both morphological and molecular characteristics in Africa., Courtney Antonia Cook, Edward Charles Netherlands, Johann van As, Nico Jacobus Smit., and Obsahuje bibliografii