Cytokiny jsou proteiny, které regulují růst, diferenciaci a aktivaci buněk. Jejich účinek se široce využívá pro léčbu zánětlivých a nádorových onemocnění. Anti-cytokinová léčba je velmi slibná, ale přinese v blízké budoucnosti velké finanční zatížení zdravotnictví., Cytokines are proteins that regulate the growth, differentiation and activation of cells. Their functions are used in therapy of inflammatory diseases and cancer. Antibody blockade of cytokines seems to be very promising, but it will result in considerable financial burden for healthcare in future., and Ilja Trebichavský.
A rise in baseline cytosolic free Ca2+ in canine vascular endothelial-like cells (VEC) lining the luminal surface of the polyester arterial prosthesis is described. In one, three and six month implantation experiments we employed six adult mongrel dogs, polyester arterial prostheses Arteknit Ra K, fluorescent Ca2+ indicator Fura-2 and digital imaging microscopy to study cytosolic free Ca2+ in cultured VEC. The electron microscopy scanning of the luminal surface in different regions of the graft were also performed. A rise in cytosolic free Ca2+ in the VEC lining the luminal surface of the prosthesis is probably the result of the immunologic reaction and mechanical stress which stimulate the proliferation activity of the endothelial cells. It seems that the baseline cytosolic free Ca2+ reflects the course of the endothelization process on the polyester arterial prosthesis., P. Ondruš, R. Alberty, P. Pothier, V. Echavé, J. Poisson, G. Bkaily., and Obsahuje bibliografii
This article aims to compare two aspects of the education systems in two East European countries. As the political history of the Czech Republic and Poland in the past fifty years is similar, the authors compare the countries' development in tackling educational inequalities and attempt to evaluate their policies and reforms from the beginning of socialism to date. Despite many similarities and identical outcomes in the past (no effect in lowering levels of educational inequalities), these countries undertook two different approaches to the transformation of higher education after 1989. The specific current developments in higher education in the Czech Republic and Poland have been caused by conservative and reserved legislation in the former and the creation of new, very liberal rules for establishing non-state higher education institutions in the latter. As there emerged a considerable difference in the number of higher education institutions in each country, the authors show the negative impact on educational inequalities and the social consequences of the enormous increase in the number of students and private universities. Despite different approaches, the countries face many similar problems, such as quality assurance, a shortage of staff, and information asymmetry. These problems seem to be sharper in Poland, but it is only a matter of time for the Czech Republic.
This article makes a plea for a more explicitly intentional and political-strategic analysis of post-communist public policy pathways. The author analyses a set of social and labour-market policies implemented in the Czech Republic (pro-active job loss prevention) compared to Hungary and Poland (large-scale non-elderly retirement), and indicates why, far from being fully constrained by structural or external variables or by international pressures, political elites were able to design policy packages that served to reduce anti-reform protests. Once enacted at a formative historical turning point, these early policies fundamentally reshaped the subsequent operational space of post-communist politics throughout the 1990s. They crystallised the distinct pathways of post-communist welfare regimes, and they enabled early, and irreversible, democratic and market reform progress. While seemingly inefficient, and definitely costly in public-fi-nance terms, these policy packages contained a degree of political rationality, as they contributed to the making of the great Czech, Hungarian, and Polish transition success stories, in an otherwise highly heterogeneous population of postcommunist transition cases.
The national report for the purpose of the 20th International Congress of Comparative Law Fukuoka 2018 deals with the optional choice of court agreements from the perspective of the Czech law. The report answers the questions if the Czech national legislation allows the parties to conclude the optional choice of court agreements in international cases, what is the character of these clauses and if they are expressly stated in the Czech Private International Law Act. The authors deal also with the asysmmetrical choice of court agreements, expecially their legal effect. in the end of the report, the authors evalueate the efficiency of the national regulation and propose for the necessary modifications., Naděžda Rozehnalová, Silvie Mahdalová, Lucie Zavadilová., and Obsahuje bibliografické odkazy
The article describes Czech women's civic organising focused on gender equality and women's rights since the Second World War and explains its character and development in the context of a) the state socialist regime, b) the impact of foreign and international donors on Czech women's civic organising during the socio-economic and political transformation of the first part of the 1990s, and c) the current process of the formalisation of Czech women's civic groups brought about by the Czech Republic's preparation for EU accession. The formalisation of women's civic groups is a process that consists of project-orien-tation, reform-orientation and the professionalisation of women's civic groups. In the era when the funding of women's civic groups has changed (as a result of EU Eastern enlargement) and the range of national political actors engaged in promoting gender equality has broadened (owing to pressure from the EU), these processes have brought about a shifts in the topics, activities, partnerships and strategies of Czech women's civic groups. These processes have contributed on the one hand to the marginalisation of those topics, activities and strategies previously addressed by some of Czech women's civic groups that do not fit in with the mainstream topics, activities and strategies defined by the EU (and by the EU influenced state). At the same time, however, some channels for having an impact on national decision-making processes have opened up to specific women's civic groups. EU Eastern enlargement paradoxically led to the orientation of women's civic groups towards national rather than supranational lobbying.
Devátý ročník tradiční české street party se konal v Bruselu 12. června 2015. Akce, kterou každoročně organizují zástupci regionů a měst ČR ve spolupráci s českými organizacemi zastoupenými v Bruselu, představila historii, tradice a kulturu České republiky; těšila se nejen velké návštěvnosti, ale i dobrému počasí. and Kateřina Slavíková.