This study has observed possible effect of ellagitannins - compounds from pomegranate on process of steroidogenesis in ovaries. The aim of the study was to investigate the possible effect of punicalagin on secretion of steroid hormones - progesterone, androstenedione, testosterone and 17β-estradiol by ovarian fragments of rabbits in vitro. Ovarian fragments from sexually mature female New Zealand white rabbits (n=20) were incubated without (control group) or with punicalagin at various doses 1, 10 and 100 μg.ml−1 for 24 h. Hormones were evaluated by ELISA (The Enzyme-Linked Immunosorbent Assay). Data showed that progesterone and 17β-estradiol (but not androstenedione and testosterone) release by rabbit ovarian fragments was significantly affected by punicalagin addition at various doses. Punicalagin (at 100 μg.ml-1) significantly (P<0.05) increased progesterone secretion. On the other hand, the release of 17β-estradiol was significantly (P<0.005) decreased by punicalagin addition (at 10 μg.ml-1). Our results suggest that punicalagin could have dose-dependent impact on secretion of steroid hormones progesterone and 17β-estradiol by rabbit ovarian fragments and it may be effector in process of ovarian steroidogenesis., D. Packova, A. A. Carbonell-Barrachina, A. Kolesarova., and Obsahuje bibliografii
O tom jak se rodily první přístupy k udržení horkého fúzního plazmatu pomocí silných elektrických a magnetických polí., Through his whole scientific career, carried out mainly at FTI Kharkov in the Soviet Union, O. A. Lavrentev (1926-2011) studied thermonuclear plasma confinement. Initially an electrostatic confinement and later a magnetic electrostatic plasma confinement was proposed by him. However, he did not describe the transition from the first to the second type of confinement, e. g., from the spherical concentric purely electrostatic trap to the magnetic trap formed by spindle cusp fields with its slits plugged by electrostatic fields, which represents the simplest type of an electromagnetic trap. This article offers a hypothesis of how O. A. Lavrentev transformed the earlier concept into the later one., Milan Řípa, Miroslav Šos., and Obsahuje bibliografii
Kolorované ilustrace a dekor., Na titulní straně signet., Na titulní straně vlastnický přípisek Simon Retter Hembavensis. Na zadní předsádce rukopisné přípisky., and Na předním přídeští viditelná makulatura rukopisu.