The Visio Pauli, one of the most popular ‘Visions’ of the Middle Ages, constitutes the European form of an originally Oriental apocrypha known as ‘The Apocalypse of Paul’. On its journey through the Latin Middle Ages this text was used in many ways, which have fundamentally influenced its textual shape. The article outlines concisely the dissemination of the Visio Pauli in the Medieval West, its incorporation into new, shifting transmission patterns and textual combinations. It will be shown that the Eastern apocrypha from late Antiquity, the Paulus-Apocalypse, and its reworked European version, the Visio Pauli – the first a closed, the second an open text – in their complex transmission histories represent two entirely different realisations of one and the same material. The analysis, however, concentrates on the specific Bohemian redaction and its Old Czech version. The shape of a text will here be conceived in terms of its dissemination and concrete uses. The focus of the investigation consists, therefore, in the ways in which the variable and open were fixed, and the circumstances, consequences and description of this process. From material to text, from text to context, or, the other way round, from context to text – these are the aspects of the literary, structural, and functional analysis of the Visio Pauli in the context of cultural history. This approach constitutes an attempt to describe the text transmission differently from conventional textual criticism, and how to think about the shape of medieval texts in the context of their concrete use and function. The article is a reworking of a lecture given at Prague and Brno in 2008 and is essentially an abridged version of the author’s Ph.D. thesis, Die Visio Pauli: Wege und Wandlungen einer orientalischen Apokryphe im lateinischen Mittelalter unter Einschlus der alttschechischen und deutschsprachigen Textzeugen, Leiden and Boston: Brill (Mittellateinische Studien und Texte 34), 2006. It is the first written presentation of this research in Czech.
Never before in history data has been generated at such high volumes as it is today. It is estimated that every year about 1 Exabyte (= 1 Million Terabyte) of data are generated, of which a large portion is available in digital form. Exploring and analyzing the vast volumes of data becomes increasingly difficult. This paper describes system Vitamin-S that aims to help when analyzing very large data sets.
V dějinách idejí se vitalismu dostalo různých definic a různé postavy byly označeny za vitalisty. Když se soustředíme na 17. století, zjistíme, že badatelé identifikovali jako vitalisty autory, kteří zastávají názory, jež jsou v diametrálním protikladu. Stručně představím názory dualistických vitalistů (Henry More, Ralph Cudworth a Nehemiah Grew) a monistických vitalistů (Francis Glisson, Margaret Cavendishová, Anne Conwayová), a filosofické a teologické uvažování, které formovalo jejich myšelní. Ve všech těchto různých podobách vitalismu se nacházejí identifikovatelné společné motivy: bytostná neredukovatelnost života (považovaná za vlastnost buď nehmotného ducha nebo samotného hmoty) a univerzalita života (sahající daleko za "organickou" oblast přírody až "anorganické")., Vitalism has been given different definitions and diverse figures have been labelled as vitalists throughout the history of ideas. Concentrating on the seventeenth century, we find that scholars identify as vitalists authors who endorse notions that are in diametrical opposition with each other. I briefly present the ideas of dualist vitalists (Henry More, Ralph Cudworth and Nehemiah Grew) and monist vitalists (Francis Glisson, Margaret Cavendish and Anne Conway) and the philosophical and theological considerations informing their thought. In all these varied forms of vitalism the identifiable common motives are the essential irreducibility of life (regarded as a property of either an immaterial spirit or matter itself) and the universality of life (extending well beyond the “organic” realm of nature, incorporating the “inorganic”)., and Veronika Szántó.
In this review we summarize recent opinions on the possible role of vitamin D in the risk of thyroid diseases development. It may be concluded from the available data that vitamin D deficiency, particularly levels below 12.5 ng/ml should be considered as an additional, but important risk factor for development of thyroid autoimmunity, both chronic autoimmune thyroiditis and Graves´ disease. A higher risk of Graves´ disease development is also associated with several polymorphisms in the gene encoding for vitamin D binding protein and for the specific receptor of active form of vitamin D - 1,25-(OH)2D3 in the respective target cells. Important for development of thyroid cancer appeared polymorphisms of genes encoding for vitamin D receptors and of genes encoding for the participating hydroxylating enzymes in thyroid tissue, leading to a diminished local 1,25-(OH)2D3 formation capacity with following alteration of antiproliferatory, antiapoptotic and prodifferentiating efficacy of the latter. Whether supplementation with high doses of vitamin D or its analogues possesses preventive or therapeutic effect is an object of intensive studies., K. Vondra, L. Stárka, R. Hampl., and Obsahuje bibliografii