We studied 52 patients with epilepsy with the average age of 36.2±14.7 years old. Of them, 38 patients had idiopathic epilepsy, 14 patients had symptomatic epilepsy. Our study has shown that epilepsy is accompanied with increased levels of autoantibodies to NF-200, GFAP, S100, MBP, DNA, GABA and dopamine receptors, testifying to the important role of autoimmune disturbances in the pathogenesis of epilepsy. More severe attacks are accompanied by worsening of neuroimmune dysregulation. The degree and duration of autoimmune process can serve additional diagnostic and prognostic criteria for epilepsies., Rano Bahodirovna Azizova, and Literatura
This review presents recent findings regarding the physiological and pathophysiological extra- and intracellular mechanisms of secretory diarrhoea. Putative interventions directed towards counteracting the mechanisms causing fluid loss, especially in relation to the enteric nervous system, intracellular mediators, and localization of fluid and electrolyte transport, are discussed. The enteric nervous system regulates the complex process of transmural fluid and electrolyte transport by controlling the function of the mucosa, the motility, and the microcirculation in both health and disease. Most of the processes, leading to secretory diarrhoea, involve activation of the enteric nervous system, with local release of neurotransmitters and other endogenous effectors, which induce chloride secretion. A new therapeutic approach is based on stimulation of absorption and inhibition of secretion by using receptor agonists and antagonists, and modulators of intracellular signal transduction. A physio-pharmacological review of serotonin and the antisecretory factor as modulators of intestinal fluid and electrolyte transport is given.
In this paper, we mainly use the properties of the minimum eigenvalue of the Fan product of $M$-matrices and Cauchy-Schwarz inequality, and propose some new bounds for the minimum eigenvalue of the Fan product of two $M$-matrices. These results involve the maximum absolute value of off-diagonal entries of each row. Hence, the lower bounds for the minimum eigenvalue are easily calculated in the practical examples. In theory, a comparison is given in this paper. Finally, to illustrate our results, a simple example is also considered.
Let u be a holomorphic function and φ a holomorphic self-map of the open unit disk D in the complex plane. We provide new characterizations for the boundedness of the weighted composition operators uCφ from Zygmund type spaces to Bloch type spaces in D in terms of u, φ, their derivatives, and φn, the n-th power of φ. Moreover, we obtain some similar estimates for the essential norms of the operators uCφ, from which sufficient and necessary conditions of compactness of uCφ follows immediately., Xin-Cui Guo, Ze-Hua Zhou., and Obsahuje seznam literatury
Different chromosomal races of the Nannospalax ehrenbergi (Nehring, 1898) complex inhabit south-eastern Turkey. In spite of the fairly restricted range of this mole rat in Turkey, no less than eight different karyotypes have been reported so far. These differ in diploid number (range from 52 to 58), fundamental number of chromosomal arms (ranging between 72 and 90) and in the fundamental number of autosomal arms (ranging from 68 to 86). The most common chromosomal form is 2n = 52, NF = 76, NFa = 72, which is known from Southeast Anatolia. In this paper I report on a new N. ehrenbergi karyotype from south-eastern Turkey. In 18 specimens investigated, the diploid number of chromosomes was 2n = 56, NF = 66, and NFa = 62. The karyotype consisted of 4 pairs of metacentrics/submetacentrics and 23 pairs of acrocentrics. The X chromosome was medium-sized submetacentric and the Y chromosome was small acrocentric. This chromosomal set is different to the most common Turkish N. ehrenbergi karyotype (2n = 52) and also differs markedly from the known chromosomal forms from Gaziantep (2n = 56, NF = 82, NFa = 78) and Tarsus (2n = 56, NF = 72, NFa = 68 ).