Omega-3 fatty acids (Ω3FA) are known to reduce hypertriglyceridemia- and inflammation-induced vascular wall diseases. However, mechanisms of their effects are not completely clear. We examined, whether 10-day Ω3FA diet can reduce bacterial lipopolysaccharide-induced changes in expression of gap junction protein connexin40 (Cx40) in the aorta of hereditary hypertriglyceridemic (hHTG) rats. After administration of a single dose of lipopolysaccharide (LPS, 1 mg/kg, i.p.) to adult hHTG rats, animals were fed with Ω3FA diet (30 mg/kg/day) for 10 days. LPS decreased Cx40 expression that was associated with reduced acetylcholine-induced relaxation of aorta. Ω3FA administration to LPS rats had partial anti-inflammatory effects, associated with increased Cx40 expression and improved endothelium dependent relaxation of the aorta. Our results suggest that 10-day Ω3FA diet could protect endothelium-dependent relaxation of the aorta of hHTG rats against LPS-induced damage through the modulation of endothelial Cx40 expression, K. Frimmel, R. Sotníková, J. Navarová, I. Bernátová, J. Križák, Z. Haviarová, B. Kura, J. Slezák, Ľ. Okruhlicová., and Obsahuje bibliografii
A space $X$ is $\mathcal L$-starcompact if for every open cover $\mathcal U$ of $X,$ there exists a Lindelöf subset $L$ of $X$ such that $\mathop {\mathrm St}(L,{\mathcal U})=X.$ We clarify the relations between ${\mathcal L}$-starcompact spaces and other related spaces and investigate topological properties of ${\mathcal L}$-starcompact spaces. A question of Hiremath is answered.
The concept of the $k$-pairable graphs was introduced by Zhibo Chen (On $k$-pairable graphs, Discrete Mathematics 287 (2004), 11–15) as an extension of hypercubes and graphs with an antipodal isomorphism. In the same paper, Chen also introduced a new graph parameter $p(G)$, called the pair length of a graph $G$, as the maximum $k$ such that $G$ is $k$-pairable and $p(G)=0$ if $G$ is not $k$-pairable for any positive integer $k$. In this paper, we answer the two open questions raised by Chen in the case that the graphs involved are restricted to be trees. That is, we characterize the trees $G$ with $p(G)=1$ and prove that $p(G \square H)=p(G)+p(H)$ when both $G$ and $H$ are trees.
In this note we study the relation between $k_R$-spaces and $k$-spaces and prove that a $k_R$-space with a $\sigma $-hereditarily closure-preserving $k$-network consisting of compact subsets is a $k$-space, and that a $k_R$-space with a point-countable $k$-network consisting of compact subsets need not be a $k$-space.
In this paper we extend the concept of an $L$-fuzzy (characteristic) left (resp. right) ideal of a ring to a semiring $R$, and we show that each level left (resp. right) ideal of an $L$-fuzzy left (resp. right) ideal $\mu $ of $R$ is characteristic iff $\mu $ is $L$-fuzzy characteristic.
This paper is concerned with square integrable quasi-derivatives for any solution of a general quasi-differential equation of $n$th order with complex coefficients $M[y] - \lambda wy = wf (t, y^{[0]}, \ldots ,y^{[n-1]})$, $t\in [a,b)$ provided that all $r$th quasi-derivatives of solutions of $M[y] - \lambda w y = 0$ and all solutions of its normal adjoint $M^+[z] - \bar{\lambda } w z = 0$ are in $L^2_w (a,b)$ and under suitable conditions on the function $f$.