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30652. Presepsin jako diagnostický a prognostický nástroj při posuzování sepse
- Creator:
- Beňovská, Miroslava, Bučková, Dana, Petříková, D., Stašek, Jan, and Gottwaldová, Jana
- Format:
- print, text, and regular print
- Type:
- model:article, article, Text, kazuistiky, and TEXT
- Subject:
- bakteriální infekce--diagnóza, sepse--diagnóza, kalcitonin--diagnostické užití--krev, biologické markery--analýza--krev, C-reaktivní protein--diagnostické užití, antigeny CD14--diagnostické užití, prognóza, mužské pohlaví, ženské pohlaví, dospělí, lidé středního věku, and staří
- Language:
- Czech and English
- Description:
- Cíl studie: Hlavním cílem studie bylo srovnat výsledky stanovení presepsinu s výsledky rutinně používané metody ke stanovení prokalcitoninu (PCT) u pacientů v septickém stavu, na jednotlivých kazuistikách pak popsat diagnostický a prognostic - ký význam presepsinu vedle PCT a jejich případné shodné či odlišné vlastnosti. Materiál a metody: Ze skupiny 70 pacientů, kteří se v daném období léčili ve FN Brno s diagnózou sepse, bylo vybráno 31 jedinců, u kterých byl delší dobu monitorován prokalcitonin a CRP. U těchto pacientů jsme stanovili presepsin. Při vyhod - nocení studie byla srovnávána skupina pacientů, kteří sepsi přežili (23 pacientů), se skupinou zemřelých (8 pacientů). Čtyři kazuistiky byly popsány detailně. K analýze presepsinu byla využita chemiluminiscenční enzymoimunoanalytická metoda na analyzátoru PATHFAST od firmy Mitsubishi Chemical. Výsledky: U vybraného souboru byly srovnány koncentrace presepsinu, prokalcitoninu a CRP mezi skupinou přeživších pacientů a těch, kteří zemřeli. K hodnocení výsledků byly použity koncentrace presepsinu, PCT a CRP při příjmu či v době stanovení diagnózy sepse, při ukončení monitorování sepse a v době dosažení maximálních hodnot sledovaných parame - trů. Statisticky významný rozdíl mezi skupinou zemřelých a uzdravených byl zaznamenán u parametrů získaných při příjmu a v době ukončení monitorování sepse, a to jak u presepsinu (P=0,023 resp. P=0,002), tak u prokalcitoninu (P=0,021 resp. P=0,0003). Na vybraných kazuistikách je vidět, že při špatné prognóze zůstává presepsin na rozdíl od prokalcitoninu vyso - ký. Závěr: Presepsin je podobně jako PCT vhodný marker pro diagnostiku, monitorování i prognózu sepse. Dle našich výsledků potvrzených nejnovějšími literárními údaji se dokonce jeví jako lepší prognostický marker než prokalcitonin, Objective: To compare the results of presepsin determination with the results of the routinely used method of procalcitonin (PCT) determination on patients with sepsis. We use individual casuistries to describe the diagnostic significance of prese - psin compared with PCT and their identical and different properties. Material and Methods: From the original cohort of patients treated for sepsis in University Hospital Brno, 31 individuals with long-term monitoring of procalcitonin and CRP sepsis markers were selected, and measured simultaneously for presepsin. The patients were further divided into two groups - 23 survivors and 8 non-survivors. Four casuistries are described in detail.Analysis of presepsin was carried out using chemiluminescent enzyme immunoassay on the fully automated POCT instrument PATHFAST from Mitsubishi Chemical. Results: The concentration of presepsin and PCT was compared between survivors and non-survivors. The evaluation of the results was based on samples from the first day after admission or development of sepsis, the day when the para - meters reached the maximum value, and the date when monitoring of the septic condition was terminated (termination of hospitalization, exitus). A statistically significant difference between both groups was found at admission and at the end of sepsis monitoring for both presepsin (P=0.023 resp. P=0.002) and PCT (P=0.021 resp. P=0.0003). The given casuistries demonstrate that presepsin stays high in cases with a bad prognosis when compared to PCT. Conclusions: Like PCT, presepsin is a suitable marker for diagnosis, monitoring and prognosis of sepsis. Our results and findings in the latest literature even indicate that presepsin is superior to procalcitonin as a prognostic marker of sepsis., Beňovská M., Bučková D., Petříková D., Stašek J., Gottwaldová J., and Literatura
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
30653. Preservation of exponential stability for equations with several delays
- Creator:
- Berezansky, Leonid and Braverman, Elena
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- exponential stability, nonoscillation, explicit stability condition, and perturbation
- Language:
- English
- Description:
- We consider preservation of exponential stability for the scalar nonoscillatory linear equation with several delays x˙ (t) + ∑m k=1 ak(t)x(hk(t)) = 0, ak(t) ≥ 0 under the addition of new terms and a delay perturbation. We assume that the original equation has a positive fundamental function; our method is based on Bohl-Perron type theorems. Explicit stability conditions are obtained.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
30654. Preservation of macroparasite species via classic plastination: an evaluation
- Creator:
- Gonzálvez, Moisés, Ortiz, Juana, Navarro, María, and Latorre, Rafael
- Format:
- print, počítač, and online zdroj
- Type:
- model:article and TEXT
- Subject:
- parazitické organismy, sbírky, parasitic organisms, collections, silicone preservation, S10 technique, 2, and 59
- Language:
- English
- Description:
- Plastination is a preservation method for biological specimens, with important advantages over classic conservation techniques with formaldehyde or alcohol. Plastinated specimens are dry, odourless, and free of carcinogenic and toxic solutions. There are only few references about the plastination of parasites. Moreover, there is no information on the effect of plastination on the morphology and morphometry of these animals. The aim of this study was to define a plastination protocol to preserve various species of parasites, namely the nematodes Parascaris equorum (Goeze, 1782); Ascaris suum Goeze, 1782 and Dirofilaria immitis (Leidy, 1856); the acanthecephalan Macracanthorhynchus hirudinaceus (Pallas, 1781); the trematodes Fasciola hepatica Linnaeus, 1758 and Dicrocoelium dendriticum (Rudolphi, 1819) and the tapeworm Taenia sp. in the best morphological and morphometric conditions. Results showed that some individuals suffered collapse (P. equorum, A. suum, and D. dendriticum). However, other parasites presented good results with almost no change after plastination (D. immitis, M. hirudinaceus and F. hepatica). In conclusion, conventional plastination allowed anatomical preservation of all helminths tested, but modifications to the protocol are needed to prevent collapse., Moisés Gonzálvez, Juana Ortiz, María Navarro, Rafael Latorre., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
30655. Preservation of properties of fuzzy relations during aggregation processes
- Creator:
- Drewniak, Józef and Dudziak, Urszula
- Format:
- bez média and svazek
- Type:
- model:article and TEXT
- Subject:
- fuzzy relation, fuzzy relation properties, fuzzy relation classes, ∗-transitivity, transitivity, aggregation functions, relation aggregation, and triangular norms
- Language:
- English
- Description:
- Diverse classes of fuzzy relations such as reflexive, irreflexive, symmetric, asymmetric, antisymmetric, connected, and transitive fuzzy relations are studied. Moreover, intersections of basic relation classes such as tolerances, tournaments, equivalences, and orders are regarded and the problem of preservation of these properties by n-ary operations is considered. Namely, with the use of fuzzy relations R1,…,Rn and n-argument operation F on the interval [0,1], a new fuzzy relation RF=F(R1,…,Rn) is created. Characterization theorems concerning the problem of preservation of fuzzy relations properties are given. Some conditions on aggregation functions are weakened in comparison to those previously given by other authors.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
30656. Preservation of rabbit hearts with different cardioplégie solutions at low temperature
- Creator:
- Poltronieri, R., Cevese, A., Bregu, R., Motta, A., and Zancanaro, C.
- Type:
- article, model:article, and TEXT
- Subject:
- isolated heart, hypothermic cardioplegia, ventricular function, ultrastructural preservation, and rabbits
- Language:
- English
- Description:
- An organ-preserving solution, including in its composition also organic molecules, prepared at the University of Wisconsin (UW), has been successfully used for preservation of liver, pancreas and kidney, and has recently been tested for long-term storage of isolated hearts. We have compared the effectiveness of the UW solution with that of a standard crystalloid cardioplegic solution (St. Thomas, ST) in the functional and structural preservation of isolated hearts. The hearts taken from 24 rabbits were mounted on a Langendorff preparation. After assessment of the left ventricular function by an intraventricular balloon, 40 ml of either cardioplegic solution were injected to arrest the hearts (12 UW and 12 ST), which were then immersed in the same solution for 4 h at 4 °C without perfusion. After this period, the hearts were normothermally reperfused with oxygenated Krebs-Henseleit solution for 30 min, and finally left ventricular function was assessed again. An electron microscopic evaluation was performed as well. Significantly higher recovery of left ventricular developed pressure (p<0.01) and of negative dP/dt (p<0.05), was observed after preservation with UW, while no difference on positive dP/dt was found. After reperfusion, left ventricular end-diastolic pressure significantly rose with ST (p<0.01), but did not change with UW; the difference between ST and UW was significant (p<0.01). Tissue water content was significantly lower in the hearts preserved with UW (p<0.05). Electron microscopic examination revealed generally good preservation with no substantial difference between the two solutions. We conclude that UW cardioplegic solution, rather than ST solution, associated with low temperature, provides better protection of isolated hearts against ischaemia and reperfusion injury after long-term preservation. This is probably due to the combined effects of antioxidants, cell- membrane impermeable substances and oncotic agents.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
30657. Preserving Czech and Slovak American Archival Material /
- Creator:
- Rechcígl, Miloslav,
- Type:
- text and studie
- Subject:
- Mezinárodní migrace, exil, kolonizace, fondy archivní, archiválie, Češi američtí, emigrace, and zahraniční archivnictví
- Language:
- English
- Rights:
- unknown
30658. President Benes of Czechoslovakia /
- Creator:
- Kozák, Jan Blahoslav,
- Type:
- text and medailony
- Subject:
- Politika, Beneš, Edvard,, politici čeští, prezidenti českoslovenští, válka druhá světová (1939-1945), okupace nacistická, politika okupační, odboj zahraniční, politické dějiny, politici, and Československo 1938-1945
- Language:
- English
- Description:
- Zvl. otisk z The University of Kansas City Review
- Rights:
- unknown
30659. President Beneš on War and Peace :
- Creator:
- Beneš, Edvard,
- Type:
- text, publikace informační, dokumenty, and projevy
- Subject:
- Politologie, Beneš, Edvard,, válka druhá světová (1939-1945), vztahy mezinárodní, myšlení politické, Československo 1938-1945, odboj, odpor, antifašismus, antikomunismus, USA, zahraniční politika, mezinárodní vztahy, and světové dějiny 1939-1945
- Language:
- English
- Rights:
- unknown
30660. President Beneš's Attempts to Reinforce Czechoslovak - Romanian Relations in 1936 /
- Creator:
- Vašek, Richard,
- Type:
- text
- Subject:
- Beneš, Edvard,, prezidenti českoslovenští, vztahy československo-rumunské, zahraniční politika, mezinárodní vztahy, světové dějiny 1918-1945, Rumunsko, and Československo 1918-1938
- Language:
- English
- Rights:
- unknown