This article deals with pairs of synonymous words in Tamil. These pairs are very frequent in modern Tamil but only a few words constituting these pairs can be considered complete synonyms. Most of them differ in meaning, emotive charge or source of origin. The pairs are arranged into several major groups according to their nature and then commented upon. The article also touches upon the question of the function of these pairs in the language.
The name Carex muricata subsp. lamprocarpa “Čelak.” (1879) is frequently used in floras for C. pairae F. W. Schultz when it is treated as a subspecies of C. muricata L. However, the combination C. muricata var. lamprocarpa was published by Wallroth in 1822. The corresponding specimen in Wallroth’s collection in PR, studied by L. Čelakovský and designated here as a lectotype, is C. muricata as it has the characteristic shiny utricles. So the combination C. muricata subsp. pairae (F. W. Schultz) Čelak. (1870) has to be used.
The Typological Database System (TDS) is a web-based service that provides integrated access to a collection of independently created typological databases. It was developed with support from NWO grant 380-30-004 / INV-03-12 and from participating universities, and provides continued availability and extended documentation for its component databases, through a uniform structure and search interface. Web technologies evolve rapidly, and the system had begun to show its age even before the end of the project in 2009, motivating migration of the data collection to an archival platform. Through its Project Call 1, CLARIN-NL granted funding for migrating the resource to a durable, archival environment and converting it to a true web service architecture.
The author in her essay briefly visits the history of thinking about democracy. However, the focus ofher contemplations is on describing the limits of contemporary democracy. One of the perils threatening thedemocratic parliamentary system is the “tyranny of the majority” in parliaments, which means that the opinionsand proposals of political minorities are being overlooked.It was Alexis de Tocqueville who defined the term “tyranny of the majority” and the author of this work tookthis term and its definition as the cornerstone of this article and applied it to the current democratic model.She also indicated what means could be used to weaken the tyranny of the majority (as well as the tyrannyof the minority) and strengthen democracy.
The contraction of gastrointestinal (GI) smooth muscles is
regulated by both Ca2+-dependent and Ca2+ sensitization
mechanisms. Proline-rich tyrosine kinase 2 (Pyk2) is involved in
the depolarization-induced contraction of vascular smooth muscle
via a Ca2+ sensitization pathway. However, the role of Pyk2
in GI smooth muscle contraction is unclear. The spontaneous
contraction of colonic smooth muscle was measured by using
isometric force transducers. Protein and phosphorylation levels
were determined by using western blotting. Pyk2 protein was
expressed in colonic tissue, and spontaneous colonic contractions
were inhibited by PF-431396, a Pyk2 inhibitor, in the presence of
tetrodotoxin (TTX). In cultured colonic smooth muscle cells
(CSMCs), PF-431396 decreased the levels of myosin light chain
(MLC20) phosphorylated at Ser19 and ROCK2 protein expression,
but myosin light chain kinase (MLCK) expression was not altered.
However, Y-27632, a Rho kinase inhibitor, increased
phosphorylation of Pyk2 at Tyr402 and concomitantly decreased
ROCK2 levels; the expression of MLCK in CSMCs did not change.
The expression of P(Tyr402)-Pyk2 and ROCK2 was increased
when CSMCs were treated with Ach. Pyk2 is involved in the
process of colonic smooth muscle contraction through the
RhoA/ROCK pathway. These pathways may provide very
important targets for investigating GI motility disorders.
We suggest a method of renorming of spaces of operators which are suitably approximable by sequences of operators from a given class. Further we generalize J. Johnsons’s construction of ideals of compact operators in the space of bounded operators and observe e.g. that under our renormings compact operators are $u$-ideals in the: space of 2-absolutely summing operators or in the space of operators factorable through a Hilbert space.