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1. Detský element v zrkadle archeologických prameňov včasného stredoveku /

Creator:
Molnárová, Martina
Type:
text and studie
Subject:
Archeologie, středověk raný, dětství, hroby, ritus pohřební, archeologie, nálezy, Slovensko od příchodu Slovanů do r. 1301, ženská otázka, rodina, děti, životní úroveň, and archeologické výzkumy, archeologie v muzeích a archivech
Language:
Slovak
Description:
Das Element des Kindes im Spiegel der archäologischen Quellen des frühen Mittelalters.
Rights:
unknown

2. Dětství Maxe Švabinského

Creator:
František Pražák
Publisher:
Václav Petr
Format:
print, text, regular print, and 50 s., [14] obr. příl. : il. ; 20 cm
Type:
model:monograph and TEXT
Subject:
Malířství, Biografie, Švabinský, Max, 1873-1962, 19.-20. století, malíři, dětství, Česko, mládí, 75.071.1, 929, (437.3), (092), 21, 8, and 75
Language:
Czech
Description:
František Pražák ; [s původní litografií Maxe Švabinského a v úpravě Cyrila Boudy], 550 čísl. výt. na ručním maršovském papíře, Bubla 6801, and Bibliofilie
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

3. Dětství vynikajících lidí českých: (studium českého ingenia)

Creator:
František Pražák
Publisher:
Jan Jiránek
Format:
print and 265, [IV] s. ; 21 cm
Type:
model:monograph and TEXT
Subject:
Biografie, 19. století, osobnosti, Česko, dětství, čeští spisovatelé, inteligence (schopnost), talent, 929-058.1, 821.162.3-051, 929, 159.956.2, 159.928.23, (437.3), (048.8), and 8
Language:
Czech
Description:
František Pražák and Obsahuje bibliografii a rejstřík
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

5. Inhibin B, follicle stimulating hormone, luteinizing hormone and testosterone during childhood and puberty in males: changes in serum concentrations in relation to age and stage of puberty

Creator:
Martin Chada, Richard Průša, Jiří Bronský, Karel Kotaška, Kateřina Kotrčová, Markéta Pechová, and Ludmila Lisá
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, dětství, puberta, childhood, puberty, male, inhibin B, 14, and 612
Language:
English
Description:
Inhibin B is a gonadal dimeric polypeptide hormone that regulates synthesis and secretion of follicle stimulating hormone (FSH) in a negative feedback loop. The aim of the present study was to determine changes in serum inhibin B, gonadotropins and testosterone concentrations during childhood and puberty in males. We studied the relationship between circulating inhibin B, gonadotropins and testosterone in serum of healthy boys during the first two years of life and then in pubertal development. Using a recently developed two-side enzyme-linked immunosorbent assay (ELISA), inhibin B levels were measured in the serum of 78 healthy boys divided into eleven age groups from birth to the end of pubertal development. In addition, serum levels of gonadotropins and testosterone were measured. Serum inhibin B, gonadotropins and testosterone increased during the first months of postnatal life. A peak in serum inhibin B and gonadotropins concentrations was observed around 3-4 months of age. There was a significant positive correlation between serum inhibin B and gonadotropins and testosterone levels during the first 2 years of life. After this early increase, serum inhibin B, gonadotropins and testosterone levels decreased significantly and remained low until puberty followed by an increase beginning with the onset of puberty. Serum levels of inhibin B reached a peak at stage G3 of puberty. Around midpuberty, inhibin B lost its positive correlation with luteinizing hormone (LH) and testosterone from early puberty, and developed a strong negative correlation with FSH, which persisted into adulthood. We conclude that inhibin B plays a key role in the regulation of the hypothalamic-pituitary-gonadal hormonal axis during male childhood and pubertal development. Inhibin B is a direct marker of the presence and function of Sertoli cells and appears to reflect testicular function in boys., M. Chada, R. Průša, J. Bronský, K. Kotaška, K. Šídlová, M. Pechová, L. Lisá., and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

6. Inhibin B, follicle stimulating hormone, luteinizing hormone, and estradiol and their relationship to the regulation of follicle development in girls during childhood and puberty

Creator:
Martin Chada, Richard Průša, Jiří Bronský, Markéta Pechová, Karel Kotaška, and Lidka Lisá
Format:
print, bez média, and svazek
Type:
article, články, model:article, and TEXT
Subject:
Fyziologie člověka a srovnávací fyziologie, dívky, dětství, puberta, girls, childhood, puberty, inhibin B, 14, and 612
Language:
English
Description:
a1_Inhibin B, produced by granulosa cells in the ovary, is a heterodimeric glycoprotein suppressing synthesis and secretion of the follicle stimulating hormone (FSH). The aim of the present study was to determine hormone profiles of inhibin B, FSH, luteinizing hormone (LH), and estradiol in girls during childhood and puberty and to evaluate whether inhibin B is a marker of follicle development. We examined the correlation between inhibin B and gonadotropins and estradiol during the first two years and across the pubertal development. Using a specific two-side enzyme-linked immunosorbent assay (ELISA), inhibin B levels were measured in the serum of 53 healthy girls divided into 8 groups according to age. In addition, serum FSH, LH, and estradiol were measured by chemiluminescent immunoassay in all serum samples. A rise in serum levels of inhibin B (55.2±7.3 ng/l, mean ± S.E.M.) and FSH (1.78±0.26 UI/l), concomitant with a moderate increment of serum LH (0.36±0.09 UI/l) and estradiol (45.8±12.2 pmol/l) concentrations was observed during the first three months of life and declined to prepubertal concentrations thereafter. A strong positive correlation between inhibin B and FSH (r = 0.48, p<0.05), LH (r = 0.68, p<0.001) and estradiol (r = 0.59, p<0.01) was demonstrated during the first 2 years of life. A rise in serum levels of inhibin B, FSH, LH, and estradiol was found throughout puberty. Inhibin B had a strong positive correlation with FSH (stage I of puberty: r = 0.64, p<0.05; stage II of puberty: r = 0.86, p<0.01), LH (I: r = 0.61, p<0.05; II: r = 0.67, p<0.05), and estradiol (II: r = 0.62, p<0.05) in early puberty. From pubertal stage II, inhibin B lost this relationship to gonadotropins and estradiol. Serum inhibin B and FSH levels increased significantly during pubertal development, with the highest peak found in stage III of puberty (133.5±14.3 ng/l), and decreased thereafter., a2_In conclusion, inhibin B is produced in a specific pattern in response to gonadotropin stimulation and plays an important role in the regulation of the hypothalamic-pituitary-gonadal axis during childhood and puberty in girls. Inhibin B is involved in regulatory functions in developing follicles and seems to be a sensitive marker of ovarian follicle development., M. Chada, R. Průša, J. Bronský, M. Pechová, L. Lisá., and Obsahuje bibliografii
Rights:
http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public

8. Literární prameny o dětech a pro děti :

Creator:
Dvořáčková-Malá, Dana,
Type:
text and studie
Subject:
Literatura pro děti a mládež (beletrie), Ulrich,, Heinrich der Klausner,, Václav, dětství, středověk, literatura středověká, Alexandreis, české země od příchodu Slovanů do roku 1306, české země 1306-1526, literatura, spisovatelé, and ženská otázka, rodina, děti, životní úroveň
Language:
Czech
Description:
Literary sources on children and for children. A paper on the comparison of the historiographic sources and the literature of the Middle Ages in the Czech lands.
Rights:
unknown

10. Současné trendy v provedení statické scintigrafie ledvin u dětí s akutní pyelonefritidou

Creator:
Táborská, Kateřina
Format:
braille, text, and regular print
Type:
model:article, article, Text, přehledy, and TEXT
Subject:
dítě, pyelonefritida--diagnóza--etiologie--komplikace--radioizotopová diagnostika, radioisotopová scintigrafie--metody--škodlivé účinky--využití, infekce močového ústrojí--diagnóza--prevence a kontrola, ledviny--abnormality--radioizotopová diagnostika, technecium 99mTc pertechnát--diagnostické užití, klinické zkoušky jako téma, lidé, dětství, pyelonefritické jizvy, statická scintigrafie ledvin, and 99mTc-DMSA
Language:
Czech and English
Description:
Statická scintigrafie ledvin je jednoduchá neinvazivní metoda založená na principu záchytu 99mTc-DMSA ve funkčním ledvinném parenchymu. Snímání se provádí s odstupem 2-4 hodin po intravenózní aplikaci. Vyšetření je standardizováno, dobře dostupné, reprodukovatelné a nevyžaduje sedaci. Je spojeno s radiační zátěží, efektivní dávka činí přibližně 1 mSv bez ohledu na věk dítěte. Senzitivita DMSA skenu pro detekci parenchymových defektů u akutní pyelonefritidy se pohybuje mezi 90-100%. DMSA sken ale neumožňuje odlišit změny vyvolané akutním zánětem od jizev. Statická scintigrafie ledvin je akceptována jako referenční metoda, která spolehlivě detekuje přítomnost pyelonefritických jizev citlivěji než ultrazvuk, ale ne dříve než s odstupem 6 měsíců po atace akutní pyelonefritidy Negativní časný DMSA sken vylučuje jizvení a někteří autoři proto navrhují u těchto dětí neprovádět mikční cystografii. Optimální vyšetřovací algoritmus, který dovede identifikovat pyelonefritické jizvy a rizikové faktory vedoucí k recidivám infekce močových cest, zatím neexistuje. Každý dosud navržený má své výhody a nevýhody a bez jejich znalosti je nelze přejímat., Renal cortical scintigraphy is a simple noninvasive method based on principle of uptake 99mTc-DMSA in functional renal parenchyma. Static imaging is performed 2-4 hours after intravenous injection. Examination is standardize, well available, reproducible and it does not need sedation. It is associated with radiation dose of approximately 1 mSv, regardless of the age of the child. The sensitivity of DMSA scan for the detection of parenchymal defects due to infections ranges from 90 to 100% but does not allow differentiation of acute pyelonephritis from renal scars. It is the reference method for detecting renal sequelae after acute pyelonephritis, is more sensitive than sonography and should be performed no sooner than 6 months after the last documented infection. This indication is widely accepted. The role of cortical scintigraphy is still largely debated in acute pyelonephritis. Some authors suggest that after a normal result of an acute DMSA scan micturating cystourethrography is unnecessary. In children with a clinical diagnosis of pyelonephritis the optimal management strategy to identify associated renal injury and to uncover risk factors for future infection does not exist. Each of them has advantages and disadvantages and without their knowledge is impossible to practise them., Táborská K., and Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public