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571282. Sternberger Volksblatt: Organ für politische, wirtschaftliche, Gemeinde-, Schul- und Vereins-Angelegenheiten der nordwestlichen Bezirke Mährens
- Type:
- model:periodicalitem and TEXT
- Language:
- Czech
- Description:
- 28
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
571283. Šternberk na Moravě, Hrad, Orfeus hrající zvířatům
- Creator:
- Giorgio di Giovanni
- Publisher:
- z Lichtenštejna, kníže,
- Subject:
- animals, lira di braccio, and Orpheus
- Description:
- Olej na dřevě (68 x 127 cm): Orfeus hraje na lira di braccio, sedí pod stromem v krajině zaplněné zvířaty., Pujmanová 1997#, 54., and Obraz pochází z knížecí lichtenštejnské sbírky na zámku v Lednici, kde je doložen 1893. O tématu srov. Exemplum: Orfeus.
- Rights:
- autorská práva www.olympos.cz
571284. Šternberk na Moravě, Vestálka Tuccia
- Creator:
- Girolamo di Benvenuto
- Subject:
- sieve, Tuccia, and Vestalis
- Description:
- Olej na desce (97 x 52 cm): vestálka Tuccia (rouška přes hlavy) stojí se sítem plným vody v ruce v krajině, napravo v dálce břeh Tiberu, u něhož Tuccie zázračně nabírá vodu na znamení své čistoty., Pujmanová 1997#, č. k. 54., and Obraz byl až do 19. století v Sieně, kde tvořil součást výzdoby pracovny nějakého místního aristokrata společně s dalšími dvěma obrazy, které zobrazují Kleopatru (Florencie, De Grassi) a Vestálku s ohněm (Chambéry). Do knížecí lichtenštenské sbírky se obraz dostal roku 1894. O tématu srov. Exemplum: Tuccia.
- Rights:
- autorská práva www.olympos.cz
571285. Sternheimovy tři hry o Casanovovi hráli v neděli…
- Creator:
- Kolman, Jaroslav
- Format:
- electronic
- Type:
- model:article and TEXT
- Language:
- Czech
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
571286. Stero črt a obrázků z Podkarpatské Rusi
- Publisher:
- Nákladem vlastním
- Format:
- regular print and 528 s. : il.
- Type:
- model:monograph, text, and TEXT
- Subject:
- České Budějovice (Česko)
- Language:
- Czech
- Description:
- Údaje o vydání: a1. vyd.
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
571287. Steroid diagnostics of 21st century in the light of their new roles and analytical tools
- Creator:
- Dušková, Michaela, Kolátorová Sosvorová, Lucie, Šimková, Markéta, Šrámková, Monika, Malíková, Mária, Horáčková, Lenka, Vítků, Jana, and Stárka, Luboslav
- Format:
- počítač and online zdroj
- Type:
- model:article and TEXT
- Subject:
- estrogeny, estrogens, pre-analytical phase, age differences, lesscommon steroids, LC-MS/MS, 14, and 612
- Language:
- English
- Description:
- The determination of steroid hormones and subsequent interpretation of results is accompanied by a range of difficulties. The amount of information that current technology can provide on the circulating concentrations of more than a hundred various steroid compounds can lead to problems with interpretation. The aim of this study is to help provide orientation in this maze of data on steroid hormones. First we focus on specific aspects arising from the pre-analytical phase of steroid determination that need to be considered when planning sampling, whether for diagnostics or research. Then, we provide a brief summary of the characteristics and diagnostic relevance of several steroid hormones and/or their metabolites: pregnenolone, 17α-hydroxypregnenolone, dehydroepiandrosterone, hydroxyderivatives of dehydroepiandrosterone, androstenedione, testosterone, estrone, estradiol, estriol, cortisol, cortisone, which in our institute are determined with validated LC-MS/MS methods. For these steroids, we also provide newly calculated reference values in fertile women according to the phase of their menstrual cycle and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
571288. Steroid hormone levels in the peripartum period: differences caused by fetal sex and delivery type
- Creator:
- Karolína Adamcová, Lucie Kolátorová Sosvorová, Škodová, T, Marie Šimková, Antonín Pařízek, Luboslav Stárka, and Michaela Dušková
- Format:
- print, bez média, and svazek
- Type:
- model:article and TEXT
- Subject:
- novorozenci, steroidy, sex, newborns, steroids, delivery, physiological range, cord blood, 14, and 612
- Language:
- English
- Description:
- Progesterone, estrogens, androgens and glucocorticoids all play important roles during pregnancy, from implantation to delivery. Focusing on selected steroid hormones in the peripartum period, we defined reference ranges measured using LS-MS/MS, and assessed relationships with maternal age, pregnancy weight gain, delivery type, and fetal sex. Samples were taken from 142 healthy women with physiological gravidity at the 37th week, during the first period of labor, and from newborn mixed cord blood. We found higher cortisol and 17-OH-pregnenolone plasma levels in mothers at the 37th week that carried male fetuses (p=0.03), but no significant differences in any studied hormones in newborns of different sex. Neither maternal age nor weight gain nor newborn birth weight had any relationships to any of the studied hormones. However, there were differences depending on vaginal versus planned cesarean section deliveries. In women carrying a male fetus we found significantly higher levels of 17-OH-pregnenolone, progesterone, cortisol, corticosterone and significantly lower levels of estradiol in those undergoing spontaneous vaginal delivery. However, we found no significant differences in the cord blood of newborn males from either delivery type. We established reference ranges for our analysis methods, which should be useful for further studies as well as in standard clinical practice., K. Adamcová, L. Kolátorová, T. Škodová, M. Šimková, A. Pařízek, L. Stárka, M. Dušková., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
571289. Steroid hormones and homocysteine in the outcome of patients with normal pressure hydrocephalus
- Creator:
- Sosvorova, L., Milan Mohapl, Hill, M., Luboslav Stárka, Marie Bičíková, Vítků, J., Radmila Kantcheva, Jiří Bešťák, and Richard Hampl
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, steroidy, homocystein, demence, steroids, homocysteine, dementia, 14, and 612
- Language:
- English
- Description:
- Normal pressure hydrocephalus (NPH) is one of a few treatable conditions of cognitive decline affecting predominately elderly people. Treatment, commonly based on the ventriculoperitoneal shunt insertion, leads to a partial or complete correction of patient's state, although its effect does not unfortunately always last. The aim of our study was to observe the changes of homocysteine and selected steroids and neurosteroids and follow-up the patients with respect to the duration of the NPH-related dementia improvement. The cerebrospinal fluid and plasma levels of cortisol, cortisone, dehydroepiandrosterone (DHEA), 7α-hydroxy-DHEA, 7β-hydroxy-DHEA, 7-oxo-DHEA, 16α-hydroxy-DHEA (all LC-MS/MS), DHEA-sulphate (DHEAS) (radioimmunoassay) and homocysteine (gas chromatography) were determined in NPH-diagnosed subjects before, during and 6, 12 and 24 months after shunt insertion. The cognitive functions ameliorated after shunt insertion and remain improved within 2 years. Changes in cerebrospinal fluid DHEAS, DHEA and its ratio, cortisone/cortisol and 16α-hydroxy-DHEA and plasma DHEAS, 7β-hydroxy-DHEA, cortisone/cortisol and homocysteine were found. Mentioned changes may contribute to the clarification of NPH pathogenesis. Altered neurosteroids levels are possible indicators to be utilized in the follow-up of NPH subjects. Moreover, plasma homocysteine may serve as an early indicator of NPH-related dementia., L. Sosvorova, M. Mohapl, M. Hill, L. Starka, M. Bicikova, J. Vitku, R. Kanceva, J. Bestak, R. Hampl., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
571290. Steroid hormones in the development of postpartum depression
- Creator:
- Antonín Pařízek, Mikešová, M., Roman Jirák, Hill, M., Michal Koucký, Andrea Pašková, Velíková, M., Katarína Adamcová, Šrámková, M., Jandíková, H., Michaela Dušková, and Luboslav Stárka
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, poporodní deprese, testosteron, estrogeny, postpartum depression, testosterone, estrogens, neuroactive steroids, 14, and 612
- Language:
- English
- Description:
- Postpartum depression affects 10-15 % women after childbirth. There is no currently generally accepted theory about the causes and mechanisms of postpartum mental disorders. The principal hypothesis concerns the association with sudden changes in the production of hormones affecting the nervous system of the mother and, on the other hand, with the ability of receptor systems to adapt to these changes. We observed changes in steroidogenesis in the period ar ound spontaneous delivery. We collected three samples of maternal blood. The first sampling was 4 weeks prior to term; the second sampling was after the onset of uterine contractions (the beginning of spontaneous labour); the third sampling was during the third stage of labour (immediately after childbirth). Additionally, we collected mixed umbilical cord blood. The almost complete steroid metabolome was analyzed by gas chroma tography-mass spectrometry followed by RIA for some steroids. Mental changes in women in the peripartum period were observed using the Hamilton Depression Rating Scale. The local Ethics Committee approved the study. We found already th e changes in androgens levels correlating with postpartum mood disorders four weeks prior to childbirth. The strongest correlations between steroid and postpartum mood change were found in venous blood samples collected from mothers after childbirth and from umbilical cord blood. The main role played testosterone, possibly of maternal origin, and estrogens originating from the fetal compartment. These results suggest that change s in both maternal and fetal steroidogenesis are involved in the development of mental changes in the postpartum period. Descriptions of changes in steroidogenesis in relation to po stpartum depression could help clarify the causes of this disease, and changes in some steroid hormones are a promising marker of mental changes in the postpartum period., A. Pařízek, M. Mikešová, R: Jirák, M. Hill, M. Koucký, A. Pašková, M. Velíková, K. Adamcová, M. Šrámková, H. Jandíková, M. Dušková, L. Stárka., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public