The aim of this study was to investigate the effects of troglitazone (TRO) - a new insulin-sensitizing agent - on some metabolic parameters in an experimental model of hypertriglyceridemia and insulin resistance, hereditary hypertriglyceridemic rats, and to compare its effects with those of vitamin E, an antioxidant agent. Three groups of the above rats were fed diets with a high content of sucrose (70 % of energy as sucrose) for four weeks. The first group was supplemented with TRO (120 mg/kg diet), the second one with vitamin E (500 mg/kg diet), and the third group served as the control. Vitamin E supplementation did not lower serum triglycerides (2.42±0.41 vs. 3.39±0.37 mmol/l, N.S.) while TRO did (1.87±0.24 vs. 3.39±0.37 mmol/l, p<0.01). Neither TRO nor vitamin E influenced the serum levels of free fatty acids (FFA). Both drugs influenced the spectrum of fatty acids in serum phospholipids - TRO increased the levels of polyunsaturated fatty acids (PUFA) n-6 (36.04±1.61 vs. 19.65±1.56 mol %, p<0.001), vitamin E increased the levels of PUFA n-3 (13.30±0.87 vs. 6.79±0.87 mol %, p<0.001) and decreased the levels of saturated fatty acids (32.97±0.58 vs. 51.45±4.01 mol %, p<0.01). In conclusion, TRO lowered the level of serum triglycerides but vitamin E did not have this effect in hypertriglyceridemic rats. Compared with TRO, vitamin E had a different effect on the spectrum of fatty acids in serum phospholipids., Š. Chvojková, L. Kazdová, J. Divišová., and Obsahuje bibliografii
The prediction of traffic accident duration is great significant for rapid disposal of traffic accidents, especially for fast rescue of traffic accidents and re- moving traffic safety hazards. In this paper, two methods, which are based on artificial neural network (ANN) and support vector machine (SVM), are adopted for the accident duration prediction. The proposed method is demonstrated by a case study using data on approximately 235 accidents that occurred on freeways located between Dalian and Shenyang, from 2012 to 2014. The mean absolute error (MAE), the root mean square error (RMSE) and the mean absolute percentage error (MAPE) are used to evaluate the performances of the two measures. The conclusions are as follows: Both ANN and SVM models had the ability to predict traffic accident duration within acceptable limits. The ANN model gets a better result for long duration incident cases. The comprehensive performance of the SVM model is better than the ANN model for the traffic accident duration prediction.
We compare a recent selection theorem given by Chistyakov using the notion of modulus of variation, with a selection theorem of Schrader based on bounded oscillation and with a selection theorem of Di Piazza-Maniscalco based on bounded A , Λ-oscillation.
The regulator equation is the fundamental equation whose solution must be found in order to solve the output regulation problem. It is a system of first-order partial differential equations (PDE) combined with an algebraic equation. The classical approach to its solution is to use the Taylor series with undetermined coefficients. In this contribution, another path is followed: the equation is solved using the finite-element method which is, nevertheless, suitable to solve PDE part only. This paper presents two methods to handle the algebraic condition: the first one is based on iterative minimization of a cost functional defined as the integral of the square of the algebraic expression to be equal to zero. The second method converts the algebraic-differential equation into a singularly perturbed system of partial differential equations only. Both methods are compared and the simulation results are presented including on-line control implementation to some practically motivated laboratory models.
Let $\tilde{f}$, $\tilde{g}$ be ultradistributions in $\mathcal Z^{\prime }$ and let $\tilde{f}_n = \tilde{f} * \delta _n$ and $\tilde{g}_n = \tilde{g} * \sigma _n$ where $\lbrace \delta _n \rbrace $ is a sequence in $\mathcal Z$ which converges to the Dirac-delta function $\delta $. Then the neutrix product $\tilde{f} \diamond \tilde{g}$ is defined on the space of ultradistributions $\mathcal Z^{\prime }$ as the neutrix limit of the sequence $\lbrace {1 \over 2}(\tilde{f}_n \tilde{g} + \tilde{f} \tilde{g}_n)\rbrace $ provided the limit $\tilde{h}$ exist in the sense that \[ \mathop {\mathrm N\text{-}lim}_{n\rightarrow \infty }{1 \over 2} \langle \tilde{f}_n \tilde{g} +\tilde{f} \tilde{g}_n, \psi \rangle = \langle \tilde{h}, \psi \rangle \] for all $\psi $ in $\mathcal Z$. We also prove that the neutrix convolution product $f \mathbin {\diamondsuit \!\!\!\!*\,}g$ exist in $\mathcal D^{\prime }$, if and only if the neutrix product $\tilde{f} \diamond \tilde{g}$ exist in $\mathcal Z^{\prime }$ and the exchange formula \[ F(f \mathbin {\diamondsuit \!\!\!\!*\,}g) = \tilde{f} \diamond \tilde{g} \] is then satisfied.
We define various ring sequential convergences on $\mathbb{Z}$ and $\mathbb{Q}$. We describe their properties and properties of their convergence completions. In particular, we define a convergence $\mathbb{L}_1$ on $\mathbb{Z}$ by means of a nonprincipal ultrafilter on the positive prime numbers such that the underlying set of the completion is the ultraproduct of the prime finite fields $\mathbb{Z}/(p)$. Further, we show that $(\mathbb{Z}, \mathbb{L}^\ast _1)$ is sequentially precompact but fails to be strongly sequentially precompact; this solves a problem posed by D. Dikranjan.
A cytoskeletal network contributes significantly to intracellular regulation of mechanical stresses, cell motility and cellular mechanics. Thus, it plays a vital role in defining the mechanical behaviour of the cell. Among the wide range of models proposed for dynamic behaviour of cytoskeleton, the soft glassy rheology model has gained special attention due to the resemblance of its predictions with the mechanical data measured from experiment. The soft glassy material, theory of soft glassy rheology and experiment on cytoskeleton has been discussed, which leads to a discussion of the unique features and flaws of the model. The soft glassy rheological model provides a unique explanation of the cytoskeleton ability to deform, flow and remodel. and Obsahuje seznam literatury
In this paper an original algorithm for tlie choice of a relevaiit
belief formula is presented. Belief forinulas are treated as external representations of internal States of cognition directed at an ontologically existing atom object. This algorithrn is based on the idea of intentional semantics and uses soft methods based on the theory of consensus and choice.
For any d≥11 we construct graphs of degree d, diameter 2, and order 825d2+O(d), obtained as lifts of dipoles with voltages in cyclic groups. For Cayley Abelian graphs of diameter two a slightly better result of 925d2+O(d) has been known \cite{MSS} but it applies only to special values of degrees d depending on prime powers.