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Start Over Format print Date 2012

23. Prof. MUDr. Jaroslav Masopust, DrSc. (*28. 1. 1929 - +23. 7. 2012)

Creator:
Průša, Richard, Palička, Vladimír, Zima, Tomáš, Engliš, Miroslav, Hyánek, Josef, Kalla, Karel, Štern, Petr, Kratochvíla, Josef, Friedecký, Bedřich, Jabor, Antonín, Bunešová, Martina, and Vávrová, Jaroslava
Format:
print, text, and regular print
Type:
model:article, article, Text, biography, biografie, and TEXT
Subject:
Masopust, Jaroslav , 1929-2012, biochemie--dějiny, dějiny 20. století, dějiny 21. století, lékaři, and diagnostické techniky molekulární--dějiny
Language:
Czech
Description:
Za profesorem Masopustem / Richard Průša, Vladimír Palička -- Setkávání s profesorem Masopustem / Tomáš Zima -- Odešel J. Masopust / Miroslav Engliš, Josef Hyánek, karel Kalla -- Jak se Jarek stal prvním profesorem klinické biochemie / Petr Štern -- Jarda... / Josef Kratochvíla -- Zamýšlení nad koncem dobrého člověka / Bedřich Friedecký, Antonín Jabor -- Osobnost, úcta, obdiv / Jaroslava Vávrová and Richard Průša, Vladimír Palička, Tomáš Zima, Miroslav Engliš, Josef Hyánek, Karel Kalla Petr Štern, Josef Kratochvíla, Bedřich Friedecký, Antonín Jabor, Martina Bunešová, Jaroslava Vávrová
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

26. Současné možnosti léčby Parkinsonovy nemoci

Format:
print, text, and regular print
Type:
model:article, article, Text, and TEXT
Subject:
lidé, Parkinsonova nemoc--farmakoterapie, levodopa--aplikace a dávkování--farmakokinetika--farmakologie--škodlivé účinky, antiparkinsonika--aplikace a dávkování--škodlivé účinky--terapeutické užití, agonisté dopaminu--aplikace a dávkování--škodlivé účinky--terapeutické užití, inhibitory katechol-O-methyltransferázy--škodlivé účinky--terapeutické užití, inhibitory MAO--aplikace a dávkování--škodlivé účinky--terapeutické užití, amantadin--aplikace a dávkování--škodlivé účinky--terapeutické užití, antidepresiva--terapeutické užití, antipsychotika--terapeutické užití, dyskineze--farmakoterapie--komplikace, and pohybové poruchy--farmakoterapie--komplikace
Language:
Czech
Description:
Literatura
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

27. Successful treatment of intracardiac and pulmonary thrombi in Behçet's disease with oral anticoagulant and immunosuppressive therapy

Creator:
Canpolat, Uğur, Yorgun, Hikmet, Akdoğan, Ali, and Aytemir, Kudret
Format:
print, text, and regular print
Type:
model:article, article, Text, kazuistiky, časopisecké články, and TEXT
Subject:
aplikace orální, dospělí, Behcetův syndrom--komplikace, kombinovaná farmakoterapie, nemoci srdce--diagnóza--farmakoterapie--etiologie, heparin--aplikace a dávkování, lidé, imunosupresiva--aplikace a dávkování, mužské pohlaví, plicní embolie--diagnóza--farmakoterapie--etiologie, and trombóza--diagnóza--farmakoterapie--etiologie
Language:
English
Description:
Behçet's disease is a multisystem chronic inflammatory disease generally presenting as recurrent oral-genital ulcers and uveitis. Vascular involvement is a common presentation. However, cardiac involvement is rare in this disorder. In this case report, we present a large right ventricular thrombus detected both in computed tomography and echocardiography in a 32 year-old male patient with complaints of fever, haemoptysis and weight loss. Intracardiac thrombus showed both clinical and radiological regression with oral anticoagulant and immunosuppressive therapy. and U. Canpolat, H. Yorgun, A. Akdoğan, K. Aytemir
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

28. The TT genotype of the MTHFR 677C > T polymorphism increases susceptibility to premature coronary artery disease in interaction with some of the traditional risk factors

Creator:
Sarecka-Hujar, Beata, Zak, Iwona, and Krauze, Jolanta
Format:
print, text, and regular print
Type:
model:article, article, Text, časopisecké články, práce podpořená grantem, and TEXT
Subject:
dospělí, nemoci koronárních tepen--genetika, ženské pohlaví, genetická predispozice k nemoci, genotyp, lidé, lipidy--krev, mužské pohlaví, methylentetrahydrofolátreduktasa (NADPH2)--genetika, polymorfismus genetický, rizikové faktory, and kouření
Language:
English
Description:
BACKGROUND: The presence of several risk factors (genetic and non-genetic) has greater impact on the risk of premature coronary artery disease (CAD) than single risk factor. OBJECTIVE: The aim of the study was to establish possible relations between genotypes and alleles of 677C>T polymorphism of MTHFR gene and some traditional risk factors e.g. elevated levels of lipid parameters and smoking in development of premature CAD. METHODS: The groups comprised 152 patients with angiographically documented premature CAD (aged 42.9 +/- 5.5) and 121 age-matched blood donors (aged 42.3 +/- 6.5) were studied. The MTHFR 677C>T polymorphism was genotyped with Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) method. RESULTS: Patients with TT genotype who simultaneously smoked had increased risk of premature CAD compared to non-smoking cases with CC genotype (OR = 24.62). We also found that individuals with TT genotype and elevated LDL-cholesterol (LDL-chol.) level had significantly higher risk of CAD (OR = 9.92) than individuals with normal LDL-chol. level and CC genotype. CONCLUSIONS: The present study shows that simultaneous presence of MTHFR TT genotype and smoking or elevated levels of LDL-chol. influences the risk of premature CAD. This findings give interesting contribution to gene-environment interaction problem that may have clinical implications in the future. and B. Sarecka-Hujar, I. Zak, J. Krauze
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

29. Therapeutic erythrocytapheresis in the initial treatment of hereditary hemochromatosis

Creator:
Řeháček, Vít, Bláha, Milan, Jiroušová, Hana, Černohorská, Jitka, and Papoušek, Petr
Format:
print, text, and regular print
Type:
model:article, article, Text, časopisecké články, and TEXT
Subject:
dospělí, staří, krevní složky - separace, transfuze erytrocytů, erytrocyty - objem, ženské pohlaví, hematokrit, hemochromatóza--krev--genetika--terapie, lidé, železo--krev, mužské pohlaví, lidé středního věku, and transferin--analýza
Language:
English
Description:
BACKGROUND: The current treatment of hereditary hemochromatosis (HH) consists of performing periodic whole blood phlebotomies. Erythrocytapheresis (EA) can remove up to three times more red blood cells per single procedure and could thus have a clinical benefit. A prospective study of 30 consecutive cases of HH were included in a periodic EA program. METHODS AND PATIENTS: EA were performed using a discontinuous flow cell separators. The protocol consisted of a bimonthly EA until normalization of the serum ferritin was reached. The aim was to reduce the total erythrocyte volume by 25-35%, eventually, to adjust the amount so that hematocrit would not drop below 0.25. RESULTS: 530 +/- 101 ml of erythrocytes were removed (median 517, range 116-761 ml). Iron depletion (ferritin < 20 microg/l) was achieved in all patients after a mean 6.9 +/- 7.6 months, median 5 months, range 1-36 months and a mean 14 EA sessions. The procedures were well tolerated and there were no severe side-effects. CONCLUSIONS: We conclude that HH patients treated with EA achieved iron depletion quickly under good conditions of tolerance. The efficacy, speed, tolerability, and more favorable schedule of an EA program facilitate treatment of HH. and V. Rehácek, M. Bláha, H. Jirousová, J. Cernohorská, P. Papousek
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

30. Užívání drog ve skupinách s obtížným přístupem k drogovým službám : situace v ČR : analýza informačních zdrojů

Creator:
Nepustil, Pavel and Česko. Národní monitorovací středisko pro drogy a drogové závislosti
Publisher:
Úřad vlády České republiky
Format:
print and 84 s. ; 23 cm
Type:
model:monograph, monograph, Text, informační publikace, and TEXT
Subject:
adiktologie, poruchy spojené s užíváním psychoaktivních látek, uživatelé drog, skupiny lidí - výčet, centra pro terapii drogových závislostí, 613.81/.84, and 178.8
Language:
Czech and English
Description:
[autoři Pavel Nepustil ... et al.] and Obsahuje bibliografie a bibliografické odkazy
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

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