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6082. IN NVPTIIS ILLVSTRISSIMI PRINCIPIS, AC DOMINI, D. IOANNIS Friderici II. Ducis Saxoniae ... Et ... Dominae Agnae, natae Principis Hessorum, Epithalamion. IOANNIS STIGELII ...
- Creator:
- Stigel, Johann and Rödinger, Christian
- Publisher:
- Rödinger, Christian
- Format:
- print and [25] ff ; 4°
- Type:
- model:monograph and TEXT
- Subject:
- století 16. and poezie
- Language:
- Latin
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
6083. IN OBITVM LIBERORVM IOANNIS PISCENI ...
- Creator:
- David Crinitus z Hlaváčova and Jiří Černý z Černého Mostu
- Publisher:
- Černý z Černého Mostu, Jiří
- Format:
- print and [6] ff ; 4°
- Type:
- model:monograph and TEXT
- Subject:
- století 16., poezie, epicedia, and 094
- Language:
- Latin
- Description:
- BCBT37157
- Rights:
- http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
6084. In silico, in vitro and in vivo approach in understanding the functional relationship between ergosterol and Rubisco
- Creator:
- Mitra, J., Narad, P., and Paul, P. K.
- Format:
- print, bez média, and svazek
- Type:
- model:article and TEXT
- Subject:
- metabolity, metabolites, enzyme activity, rajče, CO2, aktivity enzymů, ergosterol, phylloplane, Rubisco, tomato, chloroplast, in silico, in vivo, large subunit, maximum carboxylation rate, 2, and 581
- Language:
- Multiple languages
- Description:
- Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco; EC 4.1.1.39) is one of the key enzymes involved in assimilation of CO2 in chloroplasts. Phylloplane microfungi and their metabolites have been reported to affect the physiology of host plants, particularly, their photosynthesis. However, information is lacking on the effect of these microflora on the physiology of chloroplasts. The current study emphasized the impact of two dominant phylloplane fungi, Aspergillus niger and Fusarium oxysporum, on activity of Rubisco in tomato chloroplasts. Ergosterol, which is a component of only fungal cell membranes and is not synthesized by plants, have been demonstrated to elicit activity of Rubisco. In the present study, it was demonstrated through in silico, in vitro, and in vivo approaches. Results demonstrated that the fungal metabolites, which contained ergosterol, could double Rubisco activity. Maximum carboxylation rate of Rubisco increased also in ergosterol-treated plants. Michaelis-Menten constant of Rubisco was also slightly affected. Ergosterol was found also to influence and enhance the binding of CO2 and ribulose-1,5-bisphosphate to Rubisco. Therefore we can postulate that the physiology of the chloroplast is probably influenced by phylloplane microfungi., J. Mitra, P. Narad, P. K. Paul., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
6085. In situ assessment of the brain microcirculation in mechanically-ventilated rabbits using sidestream dark-field (SDF) imaging
- Creator:
- Šitina, M., Zdeněk Turek, Renata Černá Pařízková, and Vladimír Černý
- Format:
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie, králíci, physiology, rabbits, SDF imaging, brain perfusion, microcirculation, 14, and 612
- Language:
- English
- Description:
- A ssessment of the cerebral microcirculation by on-line visualization has been impossible for a long time. Sidestream dark-field (SDF) imaging is a relatively new method allowing direct visualization of cerebral surface layer microcirculation using hand-held probe for direct contact with target tissue. The aim of this study was to elucidate the feasibility of studying the cerebral microcirculation in situ by SDF imaging and to assess the basic cerebral microcirculatory parameters in mechanically ventilated rabbits. Images were obtained using SDF imaging from the surface of the brain via cranio tomy. Clear high contrast SDF images were successfully obtained. Total small-vessel density was 14.6±1.8 mm/mm 2 , total all-vessel density was 17.9±1.7 mm/mm2, DeBacker score was 12.0±1.6 mm-1 and microvascular flow index was 3.0±0.0. This method seems to be applicable in animal studies with possibility to use SDF imaging also intraoperatively, providing unique opportunity to study cerebral microcirculation during various ex perimental and clinical settings., M. Šitina ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
6086. In situ assessment of the liver microcirculation in mechanically ventilated rats using sidestream dark-field imaging
- Creator:
- Vladimír Černý, Zdeněk Turek, and Renata Černá Pařízková
- Format:
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, fyziologie, krysa obecná, physiology, Rattus rattus, sidestream dark-field (SDF) imaging, liver perfusion, intermittent positive pressure ventilation, 14, and 612
- Language:
- English
- Description:
- Assessment of hepatic microcirculation by on-line visualization has been impossible for a long time. Sidestream dark-field (SDF) imaging is a relatively new method allowing direct visualization of both mucosal microcirculation and surface layers microcirculation of solid organs using hand-held probe for direct contact with target tissue. The aim of this study was to evaluate the feasibility of studying the rat hepatic microcirculation in situ by SDF imaging. The liver lobes were left in situ, and images were obtained using SDF imaging on the surface of the liver via upper midline laparotomy. Images were captured intermittently during 10-sec apnoea and recorded. The microvascular parameters were compared with previous validation studies. Clear high contrast SDF images were successfully obtained. Quantitative analysis revealed a mean FSD (functional sinusoidal density) of 402±15 cm/cm2, a sinusoidal diameter of 10.2±0.5 μm and postsinusoidal venular diameter of 33.9±13 μm. SDF imaging is a suitable noninvasive method for accurate quantification of the basic microcirculatory parameters of the liver in situ without a need to exteriorize the liver lobes. This method seems to be applicable in animal studies with possibility to use SDF imaging also intraoperatively, providing unique opportunity to study liver microcirculation during various experimental and clinical settings., V. Černý, Z. Turek, R. Pařízková., and Obsahuje seznam literatury
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
6087. In the Shadow of the Conservatoire: the Prague Organists College (1830-1889/1890)
- Creator:
- Michaela Freemanová
- Format:
- print, bez média, and svazek
- Type:
- article, studie, studies, model:article, and TEXT
- Subject:
- 19. století, dějiny hudby, hudební instituce a organizace, hudební školy, hudební život, muzikologie, history of music, music institutions, music schools, musical life, musicology, Praha (Česko), Prague (Czechia), 78.01, 373/378:78, 78:061.23, 78(091), 78-027.22, and (048.8)
- Language:
- Czech
- Description:
- Studie Michaely Freemanové se zabývá působením pražské varhanické školy, která patřila k významným vzdělávacím institucím v čechách v 19. století., In the early decades of the 19th century, three important music institutions were founded in Prague – the Tonkünstler Wittwen-und-Waisen Societät, the Conservatoire and the Organists College, opened in 1830 by the Verein der Kunstfreunde für Kirchenmusik in Böhmen (the Society for Sacred Music in Bohemia, founded in 1826). The aim of the Society was to awaken an interest among the wider public in sacred music which, at that time, was neglected and in decline. The Organists College offered tuition to members of the Christian churches as well as to Jewish communities. During the one-year course, later extended to two, and subsequently to three years, the organists, and later also choirmasters, acquired a knowledge of harmony, counterpoint, figured bass, improvisation and composition, and also learnt how to perform sacred music. The school was attended by numerous outstanding musicians, from home and abroad, among them Antonín Dvořák and Leoš Janáček; in 1890, it merged with the Prague Conservatoire., Michaela Freenamová., Rubrika: Studie, and České resumé na s. 392, anglický abstrakt na s. 369.
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
6088. In vitro antiproliferative and antiangiogenic effects of Flavin7®
- Creator:
- Ján Mojžiš, Šarišský, M., Martina Pilátová, Viktória Vohárová, Varinská, L., Mojžišová, G., Alexander Ostró, Peter Urdzík, Róbert Dankovčík, and Ladislav Mirossay
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Experimentální medicína, experimentální medicína, polyfenoly, experimental medicine, polyphenols, antiproliferative, antiangiogenic, Flavin7, 14, and 616-092
- Language:
- English
- Description:
- Flavin7 (F7) is a nutritional supplement often taken by cancer patients in Central Europe during chemo- and radiation therapy. In this study, investigation of the antiproliferative and antiangiogenic activities of this supplement were performed. Flavin7 showed antiprolif erative activity in Jurkat as well as in HeLa cells. It significantly reduced the growth of both cancer cell lines at the doses of 200 μg/ml to 20 μg/ml (p<0.001 and p<0.01, respectively). In F7-treated Jurkat cells we found a significant increase in the fraction of cells with sub-G0/G1 DNA content, which is considered to be a marker of apoptotic cell death. Apoptosis was also confirmed by annexin V staining and DNA fragmentation. Furthermore, F7 at the doses of 100 μg/ml to 4 μg/ml inhibited endothelial cell migration and capillary tube formation what indicates its potential antiangiogenic properties. Flavin7 also inhibited the activity of matrix metalloproteinases (MMPs), preferentially MM P-9, at the doses of 100 μg/ml to 4 μg/ml. Our data suggest that F7 possesses marked antiproliferative and antiangiogenic properties in vitro. Further research is needed to elucidate also its in vivo activities., J. Mojžiš, M. Šarišský, M. Pilátová, V. Voharová, L. Varinská, G. Mojžišová, A. Ostro, P. Urdzík, R. Dankovčik, L. Mirossay., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
6089. In vitro assessment of iron effect on porcine ovarian granulosa cells: secretory activity, markers of proliferation and apoptosis
- Creator:
- Kolesarova, A., Capcarova, M., Medvedova, M., Alexander V. Sirotkin, and Kovacik, J.
- Format:
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, železo, progesteron, apoptóza, iron, progesterone, apoptosis, IGF-I, proliferation, granulosa cell, 14, and 612
- Language:
- English
- Description:
- t would be desirable to expand the existing general knowledge concerning direct action of metals on the ovary. Nevertheless, the results of testing of iron compound on porcine ovarian cells should be interpreted carefully because iron is an essential element which could also induce changes in cellular processes. The aim of this in vitro study was 1) to examine dose-dependent effects of iron on the secretory activity of porcine ovarian granulosa cells, and 2) to outline the potential intracellular mediators mediating these effects. Specifically, we evaluated the effect of iron sulphate on the release of insulin-like growth factor I (IGF-I) and progesterone, as well as the expression of markers of proliferation (cyclin B1) and apoptosis (caspase-3) in porcine ovarian granulosa cells. Concentrations of IGF-I and progesterone were determined by RIA, cyclin B1 and caspase-3 expression by immunocytochemistry (ICC). Our results show a significantly decreased IGF-I secretion by ovarian granulosa cells after iron sulphate addition at the doses 0.5 and 1.0 mg/ml. The iron sulphate additions at do ses 0.17 and 1.0 mg/ml had no effect on progesterone secretion. In contrast, iron sulphate addition at doses 0.17-1.0 mg/ml resulted in stimulation of cyclin B1 and caspase-3 expression. In conclusion, the present results indicate a direct effect of iron on 1) secretion of growth factor IGF-I but not steroid hormone progesterone, 2) expression of markers of proliferation (cyclin B1), or 3) apoptosis (caspase-3) of porcine ovarian granulosa cells. These results support an idea that iron could play a regulatory role in porcine ovarian function: hormone release, prolif eration and apoptosis., A. Kolesarova ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public
6090. In vitro changes in secretion activity of rat ovarian fragments induced by molybdenum
- Creator:
- Roychoudhury, S., Detvanova, L., Alexander V. Sirotkin, Toman, R., and Kolesarova, A.
- Format:
- print, bez média, and svazek
- Type:
- article, články, model:article, and TEXT
- Subject:
- Fyziologie člověka a srovnávací fyziologie, molybden, progesteron, molybdenum, progesterone, rat ovary, estradiol, IGF-I, 14, and 612
- Language:
- English
- Description:
- The aim of this in vitro study was to examine the secretion activity (progesterone, 17β-estradiol and insulin-like growth factor-I) of rat ovarian fragments after molybdenum (Mo) addition. Rat ovarian fragments were incubated with ammonium molybdate (NH4)6Mo7O24.4H2O at the doses 90, 170, 330 and 500 μg.ml-1 for 24 h and compared with control group without Mo addition. Release of progesterone (P4), estradiol (17β-estradiol) and insulin-like growth factor I (IGF-I) by ovarian fragments was assessed by radioimmunoassay (RIA). Data show that P4 release by ovarian fragments was not affected by (NH4)6.Mo7O24.4H2O addition at all the doses used (90-500 μg.ml-1). However, addition of ammonium molybdate was found to cause a significant (P<0.05) dose-dependent decrease (at the doses 90, 170 and 500 μg.ml-1) in release of 17β-estradiol by ovarian fragments in comparison to control. Also, addition of ammonium molybdate significantly (P<0.05) inhibited IGF-I release at all the doses (90-500 μg.ml-1) used in the study. Results suggest ammonium molybdate induced inhibition in the release of growth factor IGF-I and its dosedependent effect on secretion of steroid hormone 17β-estradiol but not progesterone. These data contribute to new insights regarding the mechanism of action of Mo on rat ovarian functions., S. Roychoudhury, L. Detvanova, A. V. Sirotkin, R. Toman, A. Kolesarova., and Obsahuje bibliografii
- Rights:
- http://creativecommons.org/licenses/by-nc-sa/4.0/ and policy:public