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Creator:
Bajgar, Jiří , Cabal, Jiří , Kassa, Jiří , and Pavlík, Michal
Format:
print , text , and regular print
Type:
model:article , article , Text , časopisecké články , práce podpořená grantem , and TEXT
Subject:
zvířata , inhibitory cholinesteráz--farmakokinetika--toxicita , cholinesterasy--metabolismus , ženské pohlaví , metabolická inaktivace , otrava organofosfáty--metabolismus , organothiofosforové sloučeniny--farmakokinetika--toxicita , krysy , potkani Wistar , and sarin--farmakokinetika--toxicita
Language:
English
Description:
BACKGROUND: The method of continual determination of the rat blood cholinesterase activity was developed to study the changes of the blood cholinesterases following different intervetions. AIMS: The aim of this study is registration of cholinesterase activity in the rat blood and its changes to demonstrate detoxification capacity of rats to inactivate sarin or VX in vivo. METHODS: The groups of female rats were premedicated (ketamine and xylazine) and cannulated to a. femoralis. Continual blood sampling (0.02 ml/min) and monitoring of the circulating blood cholinesterase activity were performed. Normal activity was monitored 1-2 min and then the nerve agent was administered i.m. (2×LD50). Using different time intervals of the leg compression and relaxation following the agent injection, cholinesterase activity was monitored and according to the inhibition obtained, detoxification capacity was assessed. RESULTS: Administration of sarin to the leg, then 1 and 5 min compression and 20 min later relaxation showed that further inhibition in the blood was not observed. On the other hand, VX was able to inhibit blood cholinesterases after this intervention. CONCLUSIONS: The results demonstrated that sarin can be naturally detoxified on the contrary to VX. Described method can be used as model for other studies dealing with changes of cholinesterases in the blood following different factors. and J. Bajgar, J. Cabal, J. Kassa, M. Pavlík
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Publisher:
[s.n.]
Format:
print , text , regular print , and 30 s.
Type:
model:monograph and TEXT
Subject:
632 , 094 , 12 , 24 , zelí , škůdci rostlin , housenky , ochrana rostlin , Staré tisky , and Ochrana rostlin. Fytopatologie
Language:
German
Description:
Tištěno švabachem and Converted from MODS 3.5 to DC version 1.8 (EE patch 2015/06/25)
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Publisher:
Hänselmann
Format:
print , text , regular print , and 198 s., 74 barev obr. příl. : il.
Type:
model:monograph and TEXT
Subject:
Zoologie , zvířata , živočichové , atlasy zoologické , systematika zvířat , ilustrace , 59 , 2 , and UL01
Language:
German
Description:
hrsg. von herrvorragendsten Künstlern und Fachgelehrten and Obsahuje rejstřík
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Creator:
Babánek, Josef
Publisher:
Nákladem okresního hospodářského spolku
Format:
regular print and 31 s. ; 20 cm
Type:
handbook , příručky , model:monograph , text , and TEXT
Subject:
udc:631 , Konspekt:24 , udc:631.811 , udc:631.816 , udc:631.82/.89 , udc:(035) , agrovoc:UA01 , Konspekt:Zemědělství. Pedologie. Agrotechnika. Agroekologie , agroterm:hnojení , agroterm:hnojiva , and agroterm:výživa rostlin
Language:
Czech
Description:
(Statement of Responsibility) pro rolnictvo česko-slovanské napsal Josef Babánek and Rok vyd. z bibliografického katalogu 19. stol.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Publisher:
Tiskárna dvorská a státní
Format:
svazek , bez média , print , text , regular print , and 11 stran ilustrace
Type:
model:monograph and TEXT
Subject:
636.09 , 24 , skot , červenka , mor skotu , ochrana zvířat , and Veterinární lékařství
Language:
Czech
Description:
Converted from MODS to DC version 1.8 (EE patch 2018/05/24)
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Creator:
Špatný, František and Mörth, Fr
Publisher:
[s. n.]
Format:
print , text , regular print , and 16 stran
Type:
model:monograph and TEXT
Subject:
Energetika , kotle parní , obsluha , 620.9 , 19 , and UP02
Language:
Czech
Description:
dle Fr. Mörtha vzdělal Fr. Špatný
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Publisher:
Frantissek Geřábek
Format:
print , text , regular print , and 29 s., 1 sklád. obr. příl.
Type:
model:monograph and TEXT
Subject:
633.521 , 094.5 , 12 , 633 , 24 , len , pěstování , zpracování , Tisky (19. století) , and Rostlinná výroba
Language:
Czech
Description:
wydané od cýs. král. společnostj hospodářské v králowstwj Českem and Converted from MODS 3.5 to DC version 1.8 (EE patch 2015/06/25)
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Publisher:
K. Ausobský
Format:
regular print and 38 s., [4] l. obr. příl. : il. ; 4°
Type:
model:monograph , text , and TEXT
Subject:
udc:7.017.4 , udc:159.937.51 , udc:535.6 , udc:(035) , barvy , barvy v umění , nauka o barvách , příručky , and České Budějovice (Česko)
Language:
Czech
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Creator:
Lambl, Jan Baptista and Hušek, Jan Hostivít
Publisher:
I. L. Kober
Format:
regular print and 151 s. : il.
Type:
model:monograph , text , and TEXT
Subject:
udc:636.5 , agrovoc:UL023 , agroterm:drůbež , agroterm:chov drůbeže , agroterm:biologie zvířat , agroterm:plemena drůbeže , and agroterm:líhnutí
Language:
Czech
Description:
seš. 13, (Statement of Responsibility) dle dobrých spisů sestavil a vlastními zkušenostmi doplnil J. H. Hušek, and S 24 vyobrazeními
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public
Creator:
František Zdeněk Skuherský
Publisher:
Fr. A. Urbánek
Format:
print , text , regular print , and 182 s. : noty ; 23 cm
Type:
model:monograph and TEXT
Subject:
Hudební teorie , hudební harmonie , 781.41 , (049) , 9 , and 781
Language:
Czech
Description:
složil F.Z. Skuherský
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public