Using the localization of nonspecific esterases, the nervous system of Polystoma indicum Diengdoh et Tandon, 1991 could be revealed in toto. The nervous system is bilaterally symmetrical. Cerebral ganglia, which are connected by a thick dorsal commissure, are present dorsal to the pharynx. From the cerebral ganglia arise five anterior pairs and four posterior pairs of nerve trunks. The anterior nerves and/or their fine branches join to form a conspicuous circumoral nerve ring complex. The posterior nerves unite in the opisthaptoral region to form two main haptoral nerves, the branches from which innervate the components of the opisthaptor. Presence of nerve cells is also revealed in association with the main nerves, more predominantly in the vicinity of the opisthaptoral suckers.