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Start Over Creator Lejčko, J.

1. Metodické pokyny pro farmakoterapii akutní a chronické nenádorové bolesti

Creator:
Doležel, Tomáš, Hakl, Marek, Kozák, Jiří, Kršiak, Miloslav, Lejčko, J., Skála, Bohumil, Sláma, Ondřej, Ševčík, P., and Vorlíček, Jiří
Type:
model:article, article, Text, směrnice pro lékařskou praxi-normy, and TEXT
Subject:
bolest--farmakoterapie--klasifikace, farmakoterapie--statistika a číselné údaje--škodlivé účinky--využití, rehabilitace--metody, psychoterapie--metody, komplementární terapie--metody, and lidé
Language:
Czech
Description:
Tomáš Doležel, M. Hakl, Jiří Kozák
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

2. Metodické pokyny pro farmakoterapii nádorové bolesti

Creator:
Doležel, Tomáš, Hakl, Marek, Kozák, Jiří, Kršiak, Miloslav, Lejčko, J., Skála, Bohumil, Sláma, Ondřej, Ševčík, Pavel, and Vorlíček, Jiří
Type:
model:article, article, Text, směrnice pro lékařskou praxi-normy, and TEXT
Subject:
bolest--farmakoterapie--klasifikace, nádory--farmakoterapie--komplikace, farmakoterapie--statistika a číselné údaje--škodlivé účinky--využití, chirurgie--metody, radioterapie--metody, and lidé
Language:
Czech
Description:
Tomáš Doležel, M. Hakl, Jiří Kozák
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public

3. The glycation products before and after therapy for acute and chronic pain

Creator:
Rokyta, R., Lejčko, J., Houdek, K., Trefil, L., Nedvídek, J., Fricová, J., and Holeček, V.
Format:
bez média and svazek
Type:
model:article and TEXT
Subject:
acute, chronic pain, glycation, and fluorescence
Language:
English
Description:
Pain increased the number of free radicals in the body. Previously, we studied changes mainly in oxygen and nitroxide free radicals and described these changes relative to the lipids and saccharides. In this article we focus on changes relative to proteins. Assessment of AGE products (advanced glycation end-products) was carried out by measuring fluorescence. Patients were divided into two groups: 15 patients with acute pain and 17 patients with chronic pain. Acute pain was associated with a variety of surgical procedures and patients were examined before and after surgical procedures. The group of patients with chronic pain suffered from various types of chronic pain, but mainly back pain. In patients with acute pain, total protein (TP) decreased after surgery, as did the level of AGE and the AGE/TP ratio. Nonetheless, post-operative pain increased. In patients with chronic pain, neither total protein, AGE, or AGE/TP changed, despite significant pain relief being reported after treatment. Changes in proteins, as biochemical markers, before and after pain treatment did not show any significant changes. In patients with acute pain, the recorded changes only lasted for 3-5 days after the operation. While in chronic pain, there were no significant changes at all. The assumption that changes in proteins, as biomarkers, would have the same importance as changes in lipids and saccharides was not proven.
Rights:
http://creativecommons.org/publicdomain/mark/1.0/ and policy:public