Autophagy can regulate cell growth, proliferation, and stability of
cell environment. Its dysfunction can be involved in a variety of
diseases. Hydrogen sulfide (H2S) is an important signaling
molecule that regulates many physiological and pathological
processes. Recent studies indicate that H2S plays an important
protective role in many diseases through influencing autophagy,
but its mechanism is not fully understood. This article reviewed
the progress about the effect of H2S on autophagy in diseases in
recent years in order to provide theoretical basis for the further
research on the interaction of H2S and autophagy and the
mechanisms involved.