In this study, the performance of three different self organization feature map (SOFM) network models denoted as SOFM1, SOFM2, and SOFM3 having neighborhood shapes, namely, SquareKohonenful, LineKohonenful, and Diamond-Kohenenful, respectively, to predict the critical factor of safety (Fs) of a widely-used artificial slope subjected to earthquake forces was investigated and compared. For this purpose, the reported data sets by Erzin and Cetin (2012) [7], including the minimum (critical) Fs values of the artificial slope calculated by using the simplified Bishop method, were utilized in the development of the SOFM models. The results obtained from the SOFM models were compared with those obtained from the calculations. It is found that the SOFM1 model exhibits more reliable predictions than SOFM2 and SOFM3 models. Moreover, the performance indices such as the determination coefficient, variance account for, mean absolute error, root mean square error, and the scaled percent error were computed to evaluate the prediction capacity of the SOFM models developed. The study demonstrates that the SOFM1 model is able to predict the Fs value of the artificial slope, quite efficiently, and is superior to the SOFM2 and SOFM3.