FeNO measurement is a validated non-invasive technique, which
is used for diagnosis and monitoring of asthma. It would be
desirable to find a reliable method to monitor allergic rhinitis (AR)
via measurement of FeNO, and/or nasal nitric oxide (nNO). The
aim of our study was the assessment of the efficacy of FeNO and
nNO as markers in AR treatment. FeNO and nNO were measured
with the portable NO analyser (NIOX MINO®) in healthy
participants and in patients with AR. The patients were examined
during the pollen season and out of it. The effect of local
corticosteroids and antihistamine therapy was observed in
patients with AR during pollen season after three weeks of
therapy. There are significant differences between FeNO and
nNO in patients with AR compared to healthy controls at all set
points of measurements. While FeNO responded well to the
treatment with both antihistamines and combined therapy, nNO
decreased only after combined therapy with antihistamines and
nasal corticosteroids. nNO monitoring alone is not a suitable
method to monitor inflammation of the upper airways in AR and
its suppression by anti-allergic treatment and should be
correlated with other markers as FeNO or symptom scores.
ADHD (attention deficit hyperactivity disorder, porucha pozornosti s hyperaktivitou) představuje z hlediska psychiatrie a psychologie jednu z nejvýznamnějších poruch dětského věku. Přes většinou prezentované multifaktoriální pojetí poruchy vyvolává ADHD kontroverze v terapeutických postupech, jak ve směru preference farmakoterapie, tak ve směru preference psychosociálních intervencí. Autorky popisují teoretické podklady a terapeutické postupy obou směrů a ukazují prospěšnost jejich vzájemného propojení. Kontroverzní postoje vycházejí spíše z osobních zaujetí, než z odborné neslučitelnosti názorů., ADHD (Attention Deficit Hyperactivity Disorder) represents one of the most important disorders in child psychiatry and psychology. Despite multifactorial attitude to ADHD has predominantly been presented, this disorder keeps eliciting controversies in therapeutic approaches, both in psychopharmacological trends and in preferences of psychosocial interventions. The authors describe theoretical basis and therapeutical methods of both trends and show benefits of their reciprocal combination. Controversial attitudes proceed mainly from personal prejudices than from scientific incompatibility of different approaches., Iva Dudová, Jana Kocourková., and Obsahuje seznam literatury