Burst activity and synaptic mechanisms in a hypothalamic network grown in culture

Title:

Burst activity and synaptic mechanisms in a hypothalamic network grown in culture

Creator:

Misgeld, U. and Swandulla, D.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:0b6ad73b-d6b9-43e1-bfbe-ec3d37cb4d32
uuid:0b6ad73b-d6b9-43e1-bfbe-ec3d37cb4d32

Subject:

cultured hypothalamic neurones, burst activity, and synaptic mechanisms

Type:

article, model:article, and TEXT

Description:

In a cultured network of rat embryonic hypothalamic cells, synaptic interaction is through GABAA-receptors, that mediate inhibition by an increase in Cl' conductance, and AMPA-receptors, that mediate excitation by an increase in monovalent cationic conductance. Changes in the balance of inhibition and excitation towards a predominance of excitation lead to phasic synchronous activity of the cells. Synaptic interaction through these receptors is thus capable of modulating neurosecretion rapidly.

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 1992 Volume:41 | Number:1

Harvested from:

CDK

Metadata only:

false