Effects of acoustic stimuli on neuronal activity in the auditory cortex of the rat

Title:

Effects of acoustic stimuli on neuronal activity in the auditory cortex of the rat

Creator:

Zhang, Y., Han, L., Xiao, X., Hu, B., Ruan, H., and Xiong, Y.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:1034078d-110e-4d7b-9c4d-d56521715f0f
uuid:1034078d-110e-4d7b-9c4d-d56521715f0f

Subject:

Fyziologie člověka a srovnávací fyziologie, zvukové signály, acoustic signals, rhythmic discharges, auditory cortex, intracellular recording, depolarization, spontaneous activity, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print

Description:

Spontaneous activity of cortical neurons exhibits alternative fluctuations of membrane potential consisting of phased depolarization called "up-state" and persistent hyperpolarization called "down-state" during slow wave sleep and anesthesia. Here, we examined the effects of sound stimuli (noise bursts) on neuronal activity by intracellular recording in vivo from the rat auditory cortex (AC). Noise bursts increased the average time in the up-state by 0.81±0.65 s (rang e, 0.27-1.74 s) related to a 10 s recording duration. The rise times of the spontaneous up-events averaged 69.41±18.04 ms (range, 40.10-119.21 ms), while those of the sound-evoked up-events were significantly shorter (p<0.001) averaging on ly 22.54±8.81 ms (range, 9.31- 45.74 ms). Sound stimulation did not influence ongoing spontaneous up-events. Our data suggest that a sound stimulus does not interfere with ongoing spontaneous neuronal activity in auditory cortex but can evoke new depolarizations in addition to the spontaneous ones., Y. Zhang ... [et al.]., and Obsahuje bibliografii a bibliografické odkazy

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2011 Volume:60 | Number:4

Harvested from:

CDK

Metadata only:

false