Association of intima-media thickness of carotid arteries with remnant lipoproteins in men and women

Title:

Association of intima-media thickness of carotid arteries with remnant lipoproteins in men and women

Creator:

Jan Piťha, Kovář, J., Zdenka Škodová, Renata Cífková, Petr Stávek, Luděk Červenka, Tomáš Šejda, Věra Lánská, and Rudolf Poledne

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:1064ac8f-301f-4b1c-8867-739a812c9cfa
uuid:1064ac8f-301f-4b1c-8867-739a812c9cfa
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, ateroskleróza, sex, lipoproteiny, lipoproteins, atherosclerosis, remnant lipoproteins, preclinical atheroslerosis, reproductive status, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The subclass of triglyceride -rich lipoproteins - remnant -like particles (RLP) seems to be strong and independent risk factor for cardiovascular disease. We eva luated the role of RLP and other risk factors (RF) with sonographically measured intima - media thickness of carotid arteries (IMT CCA) in a cohort of Czech population including women defined according to the time after menopause. We investigated relation of IMT CCA to age, weight, central obesity, plasma lipids including remnant -like particles cholesterol (RLP -C) and triglycerides (RLP -TG) in 136 men and 160 women. Using multiple linear regression analysis, significant association between IMT CCA and RLP -C was found in women 1 -7 years after menopause. In the whole group of women, only age and fasting blood glucose were independently associated with IMT CCA. In men only age significantly correlated wit h IMT CCA. Significant decrease of all plasma lipids betwe en 1988 and 1996 in men was detected, while in women significant increase in triglycerides and no change in non -HDL cholesterol was observed. RLP -C was the strongest independent RF for atherosclerosis in postmenopausal women but its as sociation with IMT CC A was limited to several years after menopause. In conclusion, women changing reproductive status could be more sensitive to atherogenic impact of remnant lipoproteins., J. Piťha, J. Kovář, Z. Škodová, R. Cífková, P. Stávek, L. Červenka, T. Šejda, V. Lánská, R. Poledne., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:Suppl 3

Harvested from:

CDK

Metadata only:

false