Effect of exercise on markers of vascular health in renal transplant recipients

Title:

Effect of exercise on markers of vascular health in renal transplant recipients

Creator:

Jiří Piťha, Králová Lesná, I., Petr Stávek, Andrea Mahrová, Bacek, J., Sekerková, A., Vladimír Teplan, and Milena Štollová

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:1d7b116b-9121-480a-8426-f7b99892e4c2
uuid:1d7b116b-9121-480a-8426-f7b99892e4c2
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, tělesná cvičení, exercises, renal transplantation, endothelial progenitor cells, circulating microparticles, asymmetric climethyl arginine, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

The cornerstone of cardiovascular risk management is lifestyle intervention including exercise which could exert favorable impact also in renal transplant recipients. Nevertheless, reliable assessment of the effect of lifestyle interventions is complicated and the available data in this population are not consistent. The aim of the study was to evaluate the effect of physical activity on selected laboratory markers of vascular health including circulating stem cells, endothelial progenitor cells, microparticles, and plasma asymmetric dimethyl arginine in renal transplant recipients. Nineteen men and 7 women were recruited in 6-month program of standardized and supervised exercise. Control group consisted of 23 men and 13 women of similar age and body mass i ndex not included into the program. One year after the transplantation, the main difference between intervention and control group was found in the change of endothelial progenitor cells (p=0.006). Surprisingly, more favorable change was seen in the contro l group in which endothelial progenitor cells significantly increased compared to the intervention group. The explanation of this finding might be a chronic activation of reparative mechanisms of vascular system in the population exposed to multiple risk factors which is expressed as relatively increased number of endothelial progenitor cells. Therefore, their decrease induced by exercise might reflect stabilization of these processes., J. Piťha, I. Králová Lesná, P. Stávek, A. Mahrová, J. Racek, A. Sekerková, V. Teplan, M. Štollová., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:6

Harvested from:

CDK

Metadata only:

false