Application of the random field theory in pet imaging - injection dose optimization

Title:

Application of the random field theory in pet imaging - injection dose optimization

Creator:

Dvořák, Jiří, Boldyš, Jiří, Skopalová, Magdaléna, and Bělohlávek, Otakar

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:36d0bdd9-daca-47a1-9096-554d40488ef8
uuid:36d0bdd9-daca-47a1-9096-554d40488ef8

Subject:

random field theory, Euler characteristic, PET imaging, and PET image quality

Type:

model:article and TEXT

Format:

bez média and svazek

Description:

This work presents new application of the random field theory in medical imaging. Results from both integral geometry and random field theory can be used to detect locations with significantly increased radiotracer uptake in images from positron emission tomography (PET). The assumptions needed to use these results are verified on a set of real and simulated phantom images. The proposed method of detecting activation (locations with increased radiotracer concentration) is used to quantify the quality of simulated PET images. Dependence of the quality on the injection dose (amount of applied radiotracer) and patient's body parameters is estimated. It is used to derive curves of constant quality determining the injection dose needed to achieve desired quality of the resulting images. The curves are compared with the formula currently used in medical practice.

Language:

English

Rights:

http://creativecommons.org/publicdomain/mark/1.0/
policy:public

Coverage:

[280]-300

Source:

Kybernetika | 2013 Volume:49 | Number:2

Harvested from:

CDK

Metadata only:

false