Response of heat shock protein 72 to repeated bouts of hyperthermia in rat skeletal muscle

Title:

Response of heat shock protein 72 to repeated bouts of hyperthermia in rat skeletal muscle

Creator:

Lee, J., Himori, K., Tatebayashi, D., Abe, M., and Yamada, T.

Identifier:

https://cdk.lib.cas.cz/client/handle/uuid:53b8168a-1835-46ac-93e0-c5e56b53f519
uuid:53b8168a-1835-46ac-93e0-c5e56b53f519
issn:0862-8408

Subject:

Fyziologie člověka a srovnávací fyziologie, hypertermie, hyperthermia, heat shock response, heat shock protein, skeletal muscle, 14, and 612

Type:

article, články, model:article, and TEXT

Format:

print, bez média, and svazek

Description:

We investigated the effects of repeated hyperthermic bouts on the heat shock response of heat s hock protein ( HSP ) 72 in skeletal muscle. Rats were assigned to control and hyperthermia groups which were exposed to heated water at 42 °C. The hyperthermia group was further divided into sub -groups: a single bout (H30) or four bouts of hyperthermia for 30 min (H30x4). There was an increase in HSP72 protein content of the H30 groups in both extensor digitorum longus (EDL) and soleus muscles. Moreover, HSP72 protein expression in H30x4 group was significantly higher than in H30 group in both EDL and soleus muscles. The HSP72 mRNA was markedly increased from control levels in the H30 and H30x4 group in both types of muscles . However, HSP72 mRNA of the H30x4 group was lower than that of the H30 group in soleus muscles. Heat shock response of HSP72 is activate d even after repeated bouts of hyperthermia, with a differential regulation between muscle types., J. Lee, K. Himori, D. Tatebayashi, M. Abe, T. Yamada., and Obsahuje bibliografii

Language:

English

Rights:

http://creativecommons.org/licenses/by-nc-sa/4.0/
policy:public

Source:

Physiological research | 2015 Volume:64 | Number:6

Harvested from:

CDK

Metadata only:

false